2026 R. Kiplin Guy: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	61	11289	10402	4890	4381	196	14320

Overview

R. Kiplin Guy is affiliated with the University of Kentucky in the United States. Their research primarily spans the field of medicine, with a focus on public health, environmental and occupational health, organic chemistry, molecular biology, infectious diseases, and epidemiology.

Their scientific contributions are concentrated in several main topics, including:

Malaria Research and Control
Research on Leishmaniasis Studies
Synthesis and Biological Evaluation
Computational Drug Discovery Methods
Trypanosoma species research and implications
Synthesis and Catalytic Reactions
Drug-Induced Hepatotoxicity and Protection

The scientist has been published frequently in the following venues:

Journal of Medicinal Chemistry
Bioorganic & Medicinal Chemistry Letters
Nature Communications
Malaria Journal
The Cambridge Structural Database

Notable recent papers authored by R. Kiplin Guy include:

Rapid repurposing of drugs for COVID-19 (2020), published in Science

Other significant papers in related research fields, though authored by collaborators, include:

Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial (2020), The Lancet Infectious Diseases
Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer (2020), Cancer Research
Synthesis and Structure-Activity Relationship of Dual-Stage Antimalarial Pyrazolo[3,4-b]pyridines (2020), Journal of Medicinal Chemistry
Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia (2023), Nature Communications

Frequent collaborators of R. Kiplin Guy include:

Jared T. Hammill
Amy L. Rice
Mofolusho O. Falade
Yizhe Chen
Scott Eagon

Best Publications

Inactivation of the p53 pathway in retinoblastoma

Nikia A. Laurie;Stacy L. Donovan;Chie Schin Shih;Jiakun Zhang

699
Citations
Chemical genetics of Plasmodium falciparum.

W. Armand Guiguemde;Anang A. Shelat;David Bouck;Sandra Duffy

667
Citations
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.

Irina N. Krylova;Elena P. Sablin;Jamie Moore;Robert X. Xu

492
Citations
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond.

Wesley C. Van Voorhis;John H. Adams;Roberto Adelfio;Roberto Adelfio;Vida Ahyong

425
Citations
A surface on the androgen receptor that allosterically regulates coactivator binding.

Eva Estébanez-Perpiñá;Leggy A. Arnold;Phuong Nguyen;Edson Delgado Rodrigues

361
Citations
Rapid repurposing of drugs for COVID-19.

R. Kiplin Guy;Robert S. DiPaola;Frank Romanelli;Rebecca E. Dutch

287
Citations
Quinolone-3-Diarylethers: A New Class of Antimalarial Drug

Aaron Nilsen;Alexis N. LaCrue;Karen L. White;Isaac P. Forquer

285
Citations
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

María Belén Jiménez-Díaz;Daniel Ebert;Yandira Salinas;Anupam Pradhan

280
Citations
Nanomolar Affinity Small Molecule Correctors of Defective ΔF508-CFTR Chloride Channel Gating

Hong Yang;Anang A. Shelat;R. Kiplin Guy;Vadiraj S. Gopinath

263
Citations
An Antagonist of Dishevelled Protein-Protein Interaction Suppresses β-Catenin–Dependent Tumor Cell Growth

Naoaki Fujii;Liang You;Zhidong Xu;Kazutsugu Uematsu

261
Citations
Identification and Characterization of the First Small Molecule Inhibitor of MDMX

Damon Reed;Ying Shen;Anang A. Shelat;Leggy A. Arnold

242
Citations
Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain.

Naoaki Fujii;Jeremy P. Mallari;Elizabeth J. Hansell;Z. Mackey

226
Citations
The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor

Eva Estébanez-Perpiñá;Jamie M.R. Moore;Ellena Mar;Edson Delgado-Rodrigues

198
Citations
Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia

Michelle L. Churchman;Jonathan Low;Chunxu Qu;Elisabeth M. Paietta

195
Citations
Targeting the Binding Function 3 (Bf3) Site of the Human Androgen Receptor Through Virtual Screening.

Nathan A. Lack;Peter Axerio-Cilies;Peyman Tavassoli;Frank Q. Han

195
Citations
Searching for new antimalarial therapeutics amongst known drugs

Jennifer L. Weisman;Ally P. Liou;Anang A. Shelat;Fred E. Cohen

184
Citations
Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities.

Peter B. Madrid;John Sherrill;Ally P. Liou;Jennifer L. Weisman

179
Citations
Global Phenotypic Screening for Antimalarials

W. Armand Guiguemde;Anang A. Shelat;Jose F. Garcia-Bustos;Thierry T. Diagana

168
Citations
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells.

Steven W. Paugh;Erik J. Bonten;Daniel Savic;Laura B. Ramsey

163
Citations
Targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells

Johanny Tonos De Leon;Aki Iwai;Clementine Feau;Yenni Garcia

163
Citations