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Biology and Biochemistry

D-Index
74
Citations
21118
World Ranking
5560
National Ranking
2641

Overview

Michael A. Dyer is affiliated with St. Jude Children's Research Hospital in the United States. Their research spans several interconnected fields within biomedical science, with a strong focus on oncology and molecular biology.

The main fields of study covered by their work include Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, key subfields are Molecular Biology, Oncology, Neurology, Cancer Research, and Pulmonary and Respiratory Medicine.

Michael A. Dyer's research covers various topics, including:

  • Neuroblastoma Research and Treatments
  • Retinal Development and Disorders
  • Single-cell and spatial transcriptomics
  • Cancer Genomics and Diagnostics
  • CAR-T cell therapy research
  • Sarcoma Diagnosis and Treatment
  • Cancer therapeutics and mechanisms

The scientist has published numerous papers in prominent venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature Communications, International Journal of Radiation Oncology*Biology*Physics, and Nature Medicine.

Selected recent papers include:

  • "A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors," 2020, Nature Medicine
  • "St. Jude Cloud: A Pediatric Cancer Genomic Data-Sharing Ecosystem," 2021, Cancer Discovery
  • "Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations," 2020, Nature Communications
  • "Neuroblastoma: When differentiation goes awry," 2022, Neuron
  • "MYCN amplification and ATRX mutations are incompatible in neuroblastoma," 2020, Nature Communications

Collaborations feature prominently in Michael A. Dyer's work. Frequent co-authors include Anand G. Patel, Elizabeth Stewart, Xin Zhou, Jacqueline L. Norrie, and Paul Geeleher.

Best Publications

  • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

    Gang Wu;Alberto Broniscer;Troy A McEachron;Charles Lu

  • Neuroblastoma: developmental biology, cancer genomics and immunotherapy

    Nai-Kong V. Cheung;Michael A. Dyer;Michael A. Dyer;Michael A. Dyer

  • A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors

    Michal Slyper;Caroline B. M. Porter;Orr Ashenberg;Julia Waldman

  • Inactivation of the p53 pathway in retinoblastoma

    Nikia A. Laurie;Stacy L. Donovan;Chie Schin Shih;Jiakun Zhang

  • Recurrent Somatic Structural Variations Contribute to Tumorigenesis in Pediatric Osteosarcoma

    Xiang Chen;Armita Bahrami;Alberto Pappo;John Easton

  • Control of Müller glial cell proliferation and activation following retinal injury.

    Michael A. Dyer;Constance L. Cepko

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • A novel retinoblastoma therapy from genomic and epigenetic analyses

    Jinghui Zhang;Claudia A. Benavente;Justina McEvoy;Jacqueline Flores-Otero

  • Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations

    Franck Tirode;Didier Surdez;Xiaotu Ma;Matthew Parker

  • Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma

    Nai-Kong V. Cheung;Jinghui Zhang;Charles Lu;Matthew Parker

  • Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina

    Michael A. Dyer;Frederick J. Livesey;Frederick J. Livesey;Constance L. Cepko;Guillermo Oliver

  • p27Kip1 and p57Kip2 Regulate Proliferation in Distinct Retinal Progenitor Cell Populations

    Michael A. Dyer;Constance L. Cepko

  • MDMX: from bench to bedside.

    Jean-Christophe W. Marine;Michael A. Dyer;Aart G. Jochemsen

  • Regulating proliferation during retinal development

    Michael A. Dyer;Constance L. Cepko

  • Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma

    Xiang Chen;Elizabeth Stewart;Anang A. Shelat;Chunxu Qu

  • Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells.

    Samantha A. Cicero;Dianna Johnson;Steve Reyntjens;Sharon Frase

  • The effects of transdermal nicotine on cognition in nonsmokers with schizophrenia and nonpsychiatric controls

    Ruth S Barr;Melissa A Culhane;Lindsay E Jubelt;Rana S Mufti

  • Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors.

    Changqi C. Zhu;Michael A. Dyer;Masanori Uchikawa;Hisato Kondoh

  • p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina.

    Michael A. Dyer;Constance L. Cepko

  • Orthotopic patient-derived xenografts of paediatric solid tumours

    Elizabeth Stewart;Sara M. Federico;Xiang Chen;Anang A. Shelat

Frequent Co-Authors

Alberto S. Pappo
Alberto S. Pappo St. Jude Children's Research Hospital
Jinghui Zhang
Jinghui Zhang St. Jude Children's Research Hospital
James R. Downing
James R. Downing St. Jude Children's Research Hospital
John Easton
John Easton St. Jude Children's Research Hospital
Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Michael Rusch
Michael Rusch St. Jude Children's Research Hospital
Richard K. Wilson
Richard K. Wilson Nationwide Children's Hospital
Gang Wu
Gang Wu Washington University in St. Louis
R. Kiplin Guy
R. Kiplin Guy University of Kentucky
David Finkelstein
David Finkelstein St. Jude Children's Research Hospital

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