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John M. Essigmann

John M. Essigmann

MIT
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
22246
World Ranking
4761
National Ranking
2305

John M. Essigmann publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where John M. Essigmann sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 215 publications — 56th percentile

56% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

John M. Essigmann D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where John M. Essigmann sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 77 D-Index — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

John M. Essigmann is affiliated with the Massachusetts Institute of Technology (MIT) in the United States. Their research spans key areas within biochemistry, genetics, molecular biology, and materials science, focusing on the interface between chemical processes and biological systems.

The primary fields of study include Biochemistry, Genetics and Molecular Biology, and Materials Science. Within these disciplines, subfields addressed in their work comprise Materials Chemistry, Molecular Biology, Cancer Research, Health, Toxicology and Mutagenesis, and Spectroscopy.

The main research topics covered by Essigmann's publications are:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Epigenetics and DNA Methylation
  • Carcinogens and Genotoxicity Assessment
  • DNA Repair Mechanisms
  • Water Treatment and Disinfection
  • Cancer Genomics and Diagnostics

Essigmann has contributed to research published in various scientific venues, with frequent publications in:

  • The Cambridge Structural Database
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Chemical Research in Toxicology
  • Journal of the American Chemical Society
  • SSRN Electronic Journal

Recent papers authored or co-authored by Essigmann include:

  • "Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice," 2021, Cell Reports
  • "Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases," 2022, Chemical Research in Toxicology
  • "Metallocalix[4]arene Polymers for Gravimetric Detection of N-Nitrosodialkylamines," 2021, Journal of the American Chemical Society
  • "Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents," 2023, NAR Cancer
  • "7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli," 2022, Nucleic Acids Research

Co-authors frequently collaborating with Essigmann include Robert G. Croy, Timothy M. Swager, Haosheng Feng, Shao-Xiong Lennon Luo, and Bogdan I. Fedeles.

Best Publications

  • Mechanisms of resistance to cisplatin.

    Maria Kartalou;John M Essigmann

  • Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.

    Michael L. Wood;Miral Dizdaroglu;Ewa Gajewski;John M. Essigmann

  • Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro

    J M Essigmann;R G Croy;A M Nadzan;W F Busby

  • Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions.

    David Wang;Deborah A. Kreutzer;John M. Essigmann

  • In vivo mutagenesis by O6-methylguanine built into a unique site in a viral genome

    Edward L. Loechler;Calvert L. Green;John M. Essigmann

  • Mechanisms of Formation, Genotoxicity, and Mutation of Guanine Oxidation Products

    William L. Neeley;John M. Essigmann

  • The chemistry and biology of aflatoxin B1: from mutational spectrometry to carcinogenesis

    Maryann E. Smela;Sophie S. Currier;Elisabeth A. Bailey;John M. Essigmann

  • Recognition of cisplatin adducts by cellular proteins.

    Maria Kartalou;John M Essigmann

  • Lethal mutagenesis of HIV with mutagenic nucleoside analogs.

    Lawrence A. Loeb;John M. Essigmann;Farhad Kazazi;Jue Zhang

  • Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver

    R G Croy;J M Essigmann;V N Reinhold;G N Wogan

  • The AlkB Family of Fe(II)/α-Ketoglutarate-dependent Dioxygenases: Repairing Nucleic Acid Alkylation Damage and Beyond

    Bogdan I. Fedeles;Vipender Singh;James C. Delaney;Deyu Li

  • Molecular recognition using corona phase complexes made of synthetic polymers adsorbed on carbon nanotubes

    Jingqing Zhang;Markita P. Landry;Paul W. Barone;Jong Ho Kim;Jong Ho Kim

  • Oxidized, deaminated cytosines are a source of C → T transitions in vivo

    Deborah A. Kreutzer;John M. Essigmann

  • Repair of an Interstrand DNA Cross-link Initiated by ERCC1-XPF Repair/Recombination Nuclease

    Isao Kuraoka;William R. Kobertz;Rafael R. Ariza;Maureen Biggerstaff

  • Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation.

    Nidhi Shrivastav;Deyu Li;John M. Essigmann

  • Isolation and characterization of human cDNA clones encoding a high mobility group box protein that recognizes structural distortions to DNA caused by binding of the anticancer agent cisplatin.

    Suzanne L. Bruhn;Pieter M. Pil;John M. Essigmann;David E. Housman

  • Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli.

    James C. Delaney;John M. Essigmann

  • Site-specifically modified oligodeoxynucleotides as probes for the structural and biological effects of DNA-damaging agents.

    Ashis K. Basu;John M. Essigmann

  • Genetic effects of thymine glycol: site-specific mutagenesis and molecular modeling studies.

    Ashis K. Basu;Edward L. Loechler;Steven A. Leadon;John M. Essigmann

  • The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin.

    Jill A. Mello;Samir Acharya;Richard Fishel;John M. Essigmann

Frequent Co-Authors

Gerald N. Wogan
Gerald N. Wogan MIT
Stephen J. Lippard
Stephen J. Lippard MIT
John D. Groopman
John D. Groopman Johns Hopkins University
Catherine L. Drennan
Catherine L. Drennan MIT
Kevin J. Yarema
Kevin J. Yarema Johns Hopkins University
Lawrence A. Loeb
Lawrence A. Loeb University of Washington
Martin G. Marinus
Martin G. Marinus University of Massachusetts Chan Medical School
Steven R. Tannenbaum
Steven R. Tannenbaum MIT
Leona D. Samson
Leona D. Samson MIT
Andrei Tokmakoff
Andrei Tokmakoff University of Chicago

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Best Scientists Citing John M. Essigmann

Esteban Domingo

Esteban Domingo

Centro de Biología Molecular Severo Ochoa

Publications: 84

Stephen J. Lippard

Stephen J. Lippard

MIT

Publications: 70

Yinsheng Wang

Yinsheng Wang

University of California, Riverside

Publications: 61

Viktor Brabec

Viktor Brabec

Czech Academy of Sciences

Publications: 57

Yves Pommier

Yves Pommier

National Institutes of Health

Publications: 54

John D. Groopman

John D. Groopman

Johns Hopkins University

Publications: 53

Susan S. Wallace

Susan S. Wallace

University of Vermont

Publications: 51

Richard D. Wood

Richard D. Wood

The University of Texas MD Anderson Cancer Center

Publications: 50

Cynthia J. Burrows

Cynthia J. Burrows

University of Utah

Publications: 47

Hiroshi Kasai

Hiroshi Kasai

University of Occupational and Environmental Health Japan

Publications: 46

Leona D. Samson

Leona D. Samson

MIT

Publications: 45

Jean Cadet

Jean Cadet

Université de Sherbrooke

Publications: 42

F. Peter Guengerich

F. Peter Guengerich

Vanderbilt University

Publications: 42

Eric T. Kool

Eric T. Kool

Stanford University

Publications: 40

Lawrence A. Loeb

Lawrence A. Loeb

University of Washington

Publications: 40

Nicholas E. Geacintov

Nicholas E. Geacintov

New York University

Publications: 39

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