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Leona D. Samson

Leona D. Samson

D-Index & Metrics

Molecular Biology

D-Index
83
Citations
27307
World Ranking
898
National Ranking
473

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Leona D. Samson is affiliated with MIT in the United States and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology, cancer research, cell biology, epidemiology, and organic chemistry.

The main topics of their work include:

  • DNA Repair Mechanisms
  • Carcinogens and Genotoxicity Assessment
  • Epigenetics and DNA Methylation
  • Genomics, phytochemicals, and oxidative stress
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • CRISPR and Genetic Engineering

Recent papers authored or co-authored by Leona D. Samson include the following:

  • Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice, 2021, Cell Reports
  • CometChip analysis of human primary lymphocytes enables quantification of inter-individual differences in the kinetics of repair of oxidative DNA damage, 2021, Free Radical Biology and Medicine
  • Molecular origins of mutational spectra produced by the environmental carcinogen N-nitrosodimethylamine and SN1 chemotherapeutic agents, 2023, NAR Cancer
  • CometChip enables parallel analysis of multiple DNA repair activities, 2021, DNA Repair
  • A DNA repair-independent role for alkyladenine DNA glycosylase in alkylation-induced unfolded protein response, 2022, Proceedings of the National Academy of Sciences

Leona D. Samson has frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • DNA Repair
  • Cell Reports
  • Free Radical Biology and Medicine
  • NAR Cancer

Frequent co-authors include:

  • Bevin P. Engelward
  • Jennifer E. Kay
  • Joshua J. Corrigan
  • Robert G. Croy
  • John M. Essigmann

Leona D. Samson was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • The Lancet Commission on pollution and health

    Philip J Landrigan;Richard Fuller;Nereus J R Acosta;Olusoji Adeyi

  • Systematic Discovery of In Vivo Phosphorylation Networks

    Rune Linding;Rune Linding;Lars Juhl Jensen;Gerard J. Ostheimer;Marcel A.T.M. van Vugt;Marcel A.T.M. van Vugt

  • Balancing repair and tolerance of DNA damage caused by alkylating agents

    Dragony Fu;Jennifer A. Calvo;Leona D. Samson

  • A new pathway for DNA repair in Escherichia coli.

    Leona Samson;John Cairns

  • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

    Lisiane B. Meira;James M. Bugni;Stephanie L. Green;Chung-Wei Lee

  • Standardizing global gene expression analysis between laboratories and across platforms

    Theodore Bammler;Richard P. Beyer;Sanchita Bhattacharya;Gary A. Boorman

  • The human gut bacterial genotoxin colibactin alkylates DNA

    Matthew R. Wilson;Yindi Jiang;Peter W. Villalta;Alessia Stornetta

  • Global response of Saccharomyces cerevisiae to an alkylating agent

    Scott A. Jelinsky;Leona D. Samson

  • ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade

    Jianfeng Shen;Zhenlin Ju;Wei Zhao;Lulu Wang

  • Inflammation-induced DNA damage, mutations and cancer.

    Jennifer Kay;Elina Thadhani;Leona Samson;Bevin Engelward

  • Base excision repair in yeast and mammals.

    Asli Memisoglu;Leona Samson

  • Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes

    Scott A. Jelinsky;Preston Estep;George M. Church;Leona D. Samson

  • Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

    Mark J. Hickman;Leona D. Samson

  • A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction.

    A. Sivaraman;J. K. Leach;S. Townsend;T. Iida

  • Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: Mechanisms for nucleotide flipping and base excision

    Albert Y. Lau;Orlando D. Schärer;Leona Samson;Gregory L. Verdine

  • A Systems Approach to Mapping DNA Damage Response Pathways

    Christopher T. Workman;H. Craig Mak;Scott McCuine;Jean-Bosco Tagne

  • Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase

    Bevin P. Engelward;Geert Weeda;Michael D. Wyatt;José L. M. Broekhof

  • Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines.

    Leona Samson;Jeffrey L. Schwartz

  • Activation of Inflammation/NF-κB Signaling in Infants Born to Arsenic-Exposed Mothers

    Rebecca C Fry;Panida Navasumrit;Chandni Valiathan;J. Peter Svensson

  • Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

    Albert Y. Lau;Michael D. Wyatt;Michael D. Wyatt;Brian J. Glassner;Brian J. Glassner;Leona D. Samson

Frequent Co-Authors

Roderick T. Bronson
Roderick T. Bronson Harvard University
David J. Hunter
David J. Hunter Harvard University
Jin Chen
Jin Chen Vanderbilt University
Terrance J. Kavanagh
Terrance J. Kavanagh University of Washington
Jennifer E. Kay
Jennifer E. Kay University of Colorado Boulder
Wei Xiao
Wei Xiao University of Saskatchewan
Trey Ideker
Trey Ideker University of California, San Diego

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