World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
12481
World Ranking
10899
National Ranking
4724

Research.com Recognitions

  • 2018 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Terrance J. Kavanagh is affiliated with the University of Washington in the United States and focuses their research primarily within the domains of biochemistry, genetics, and molecular biology, with additional contributions to medicine. Their work encompasses several subfields including molecular biology, health, toxicology and mutagenesis, cardiology and cardiovascular medicine, immunology, and materials chemistry.

Kavanagh's research addresses a range of topics, with a particular emphasis on the effects and risks of endocrine disrupting chemicals. Other main topics include advanced biosensing and bioanalysis techniques, RNA and protein synthesis mechanisms, interferon and immune responses, epigenetics and DNA methylation, nanoparticles synthesis and applications, as well as studies related to diet and metabolism.

Their recent publications demonstrate involvement in diverse biomedical and toxicological research. Notable papers include:

  • "Elamipretide (SS-31) treatment attenuates age-associated post-translational modifications of heart proteins" (2021, GeroScience)
  • "Neonatal Exposure to BPA, BDE-99, and PCB Produces Persistent Changes in Hepatic Transcriptome Associated With Gut Dysbiosis in Adult Mouse Livers" (2021, Toxicological Sciences)
  • "Vitamin C is a source of oxoaldehyde and glycative stress in age-related cataract and neurodegenerative diseases" (2020, Aging Cell)
  • "Carbonyl Reductase 1 Plays a Significant Role in Converting Doxorubicin to Cardiotoxic Doxorubicinol in Mouse Liver, but the Majority of the Doxorubicinol-Forming Activity Remains Unidentified" (2020, Drug Metabolism and Disposition)
  • "Persistence of improved glucose homeostasis in Gclm null mice with age and cadmium treatment" (2021, Redox Biology)

Frequent co-authors collaborating with Kavanagh include Collin C. White, James W. MacDonald, Theo K. Bammler, Joe Jongpyo Lim, and Joseph L. Dempsey, highlighting ongoing research partnerships and interdisciplinary approaches.

Their publications have appeared in specialized venues such as Drug Metabolism and Pharmacokinetics, GeroScience, Toxicological Sciences, Drug Metabolism and Disposition, and Aging Cell. This reflects a consistent focus on biochemical pharmacology, toxicology, and aging-related biomedical research.

Terrance J. Kavanagh was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2018, indicating peer acknowledgment within the scientific community.

Best Publications

  • Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression

    Isaac S. Harris;Aislinn E. Treloar;Satoshi Inoue;Masato Sasaki

  • Standardizing global gene expression analysis between laboratories and across platforms

    Theodore Bammler;Richard P. Beyer;Sanchita Bhattacharya;Gary A. Boorman

  • Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

    Christopher C. Franklin;Donald S. Backos;Isaac Mohar;Collin C. White

  • Glutathione redox potential in response to differentiation and enzyme inducers

    Ward G Kirlin;Jiyang Cai;Sally A Thompson;Dolores Diaz

  • Fluorescence-based microtiter plate assay for glutamate-cysteine ligase activity.

    Collin C White;Hannah Viernes;Cecile M Krejsa;Dianne Botta

  • Organophosphorus insecticides chlorpyrifos and diazinon and oxidative stress in neuronal cells in a genetic model of glutathione deficiency.

    Gennaro Giordano;Zhara Afsharinejad;Marina Guizzetti;Annabella Vitalone

  • Glutamate Cysteine Ligase Modifier Subunit Deficiency and Gender as Determinants of Acetaminophen-Induced Hepatotoxicity in Mice

    Lisa A. McConnachie;Isaac Mohar;Francesca N. Hudson;Carol B. Ware

  • De novo synthesis of glutathione is required for both entry into and progression through the cell cycle.

    Martin Poot;Heidi Teubert;Peter S. Rabinovitch;Terrance J. Kavanagh

  • Role of Oxidative Stress in the Action of Vanadium Phosphotyrosine Phosphatase Inhibitors REDOX INDEPENDENT ACTIVATION OF NF-κB

    Cecile M. Krejsa;Steven G. Nadler;James M. Esselstyn;Terrance J. Kavanagh

  • Mitochondrial‐targeted peptide rapidly improves mitochondrial energetics and skeletal muscle performance in aged mice

    Michael P. Siegel;Shane E. Kruse;Justin M. Percival;Jorming Goh

  • Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.

    David M. Krzywanski;Dale A. Dickinson;Karen E. Iles;Amanda F. Wigley

  • Flow cytometric analysis of cell cycle-dependent changes in cell thiol level by combining a new laser dye with Hoechst 33342.

    Martin Poot;Terrance J. Kavanagh;Hee Chol Kang;Richard P. Haugland

  • Disruption of Redox Homeostasis in Tumor Necrosis Factor-Induced Apoptosis in a Murine Hepatocyte Cell Line

    Robert H. Pierce;Jean S. Campbell;Alyssa B. Stephenson;Christopher C. Franklin

  • Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium.

    James C. Bonner;Rona M. Silva;Alexia J. Taylor;Jared M. Brown

  • Induction of Glutathione Synthesis in Macrophages by Oxidized Low-Density Lipoproteins Is Mediated by Consensus Antioxidant Response Elements

    Florian Bea;Francesca N. Hudson;Alan Chait;Terrance J. Kavanagh

  • Neurotoxicity of a polybrominated diphenyl ether mixture (DE-71) in mouse neurons and astrocytes is modulated by intracellular glutathione levels.

    Gennaro Giordano;Terrance J. Kavanagh;Lucio G. Costa;Lucio G. Costa

  • Gender differences in brain susceptibility to oxidative stress are mediated by levels of paraoxonase-2 expression

    G. Giordano;L. Tait;C.E. Furlong;T.B. Cole

  • The role of mitochondrial and oxidative injury in BDE 47 toxicity to human fetal liver hematopoietic stem cells.

    Jing Shao;Collin C. White;Michael J. Dabrowski;Terrance J. Kavanagh

  • Enhanced Acetaminophen Hepatotoxicity in Transgenic Mice Overexpressing BCL-2

    Michael L Adams;Robert H Pierce;Mary Eliabeth Vail;Collin C White

  • Sulfhydryl oxidation down-regulates T-cell signaling and inhibits tyrosine phosphorylation of phospholipase C gamma 1.

    Steven B. Kanner;Terrance J. Kavanagh;Angelika Grossmann;Shiu Lok Hu

Frequent Co-Authors

Charles L. White
Charles L. White The University of Texas Southwestern Medical Center
Lucio G. Costa
Lucio G. Costa University of Washington
Peter S. Rabinovitch
Peter S. Rabinovitch University of Washington
Xiaohu Gao
Xiaohu Gao University of Washington
Nelson Fausto
Nelson Fausto University of Washington
Paul T. Anastas
Paul T. Anastas Yale University
Bryan W. Brooks
Bryan W. Brooks Baylor University
Joel D. Kaufman
Joel D. Kaufman University of Washington
Julie B. Zimmerman
Julie B. Zimmerman Yale University
Martin Poot
Martin Poot University of Würzburg

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