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Biology and Biochemistry

D-Index
48
Citations
8665
World Ranking
18367
National Ranking
1256

Overview

Olaf Jahn is affiliated with the Max Planck Society in Germany and has contributed extensively to research in biochemistry, genetics, molecular biology, neuroscience, and medicine. Their research spans several key subfields including molecular biology, developmental neuroscience, cellular and molecular neuroscience, neurology, and physiology.

The main topics covered in Olaf Jahn's work include:

  • Neurogenesis and neuroplasticity mechanisms
  • RNA research and splicing
  • Neuroinflammation and neurodegeneration mechanisms
  • Alzheimer's disease research and treatments
  • Neuroscience and neuropharmacology research
  • RNA regulation and disease
  • Genetics and neurodevelopmental disorders

Their recent published papers demonstrate a focus on myelin biology and central nervous system function. These include:

  • "White matter integrity in mice requires continuous myelin synthesis at the inner tongue," 2022, Nature Communications
  • "Proteome profile of peripheral myelin in healthy mice and in a neuropathy model," 2020, eLife
  • "The CNS Myelin Proteome: Deep Profile and Persistence After Post-mortem Delay," 2020, Frontiers in Cellular Neuroscience
  • "Oligodendroglial fatty acid metabolism as a central nervous system energy reserve," 2024, Nature Neuroscience
  • "Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice," 2022, eLife

Olaf Jahn frequently collaborates with several researchers. The most common co-authors include:

  • Lars Piepkorn
  • Hauke Werner
  • Wiebke Möbius
  • Klaus-Armin Nave
  • Sophie B. Siems

Their work is regularly published in specific scientific venues, with multiple publications in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Neurochemistry
  • eLife
  • Nature Neuroscience

Best Publications

  • TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein.

    Adeline Heurich;Heike Hofmann-Winkler;Stefanie Gierer;Thomas Liepold

  • Protein corona of nanoparticles: distinct proteins regulate the cellular uptake.

    Sandra Ritz;Susanne Schöttler;Niklas Kotman;Grit Baier

  • Proteome Analysis of Arabidopsis Leaf Peroxisomes Reveals Novel Targeting Peptides, Metabolic Pathways, and Defense Mechanisms

    Sigrun Reumann;Lavanya Babujee;Changle Ma;Stephanie Wienkoop

  • Myelin proteomics: molecular anatomy of an insulating sheath.

    Olaf Jahn;Stefan Tenzer;Hauke B. Werner

  • Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease

    Stephanie Bertram;Ilona Glowacka;Marcel A. Müller;Hayley Lavender

  • Calmodulin and Munc13 form a Ca2+ sensor/effector complex that controls short-term synaptic plasticity

    Harald J. Junge;Jeong Seop Rhee;Olaf Jahn;Frédérique Varoqueaux

  • Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

    Hauke B. Werner;Katja Kuhlmann;Siming Shen;Marina Uecker

  • Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.

    Hiroshi Kawabe;Antje Neeb;Kalina Dimova;Samuel M. Young

  • Quantitative and integrative proteome analysis of peripheral nerve myelin identifies novel myelin proteins and candidate neuropathy loci

    Julia Patzig;Olaf Jahn;Stefan Tenzer;Sven P. Wichert

  • Identification and characterization of a stress-inducible and a constitutive small heat-shock protein targeted to the matrix of plant peroxisomes.

    Changle Ma;Martin Haslbeck;Lavanya Babujee;Olaf Jahn

  • Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting

    Christoph Biesemann;Mads Grønborg;Elisa Luquet;Elisa Luquet;Sven P Wichert

  • Tim50’s presequence receptor domain is essential for signal driven transport across the TIM23 complex

    Christian Schulz;Oleksandr Lytovchenko;Jonathan Melin;Agnieszka Chacinska;Agnieszka Chacinska

  • Systematic approaches to central nervous system myelin

    Patricia de Monasterio-Schrader;Olaf Jahn;Olaf Jahn;Stefan Tenzer;Sven P. Wichert

  • SNARE Protein Recycling by αSNAP and βSNAP Supports Synaptic Vesicle Priming

    Andrea Burgalossi;Sangyong Jung;Guido Meyer;Wolf J. Jockusch

  • Synaptic UNC13A protein variant causes increased neurotransmission and dyskinetic movement disorder.

    Noa Lipstein;Nanda M. Verhoeven-Duif;Francesco E. Michelassi;Nathaniel Calloway

  • Actions of CRF and its analogs.

    Klaus Eckart;Jelena Radulovic;Marko Radulovic;Olaf Jahn

  • Widespread Expression of Erythropoietin Receptor in Brain and Its Induction by Injury.

    Christoph Ott;Henrik Martens;Imam Hassouna;Imam Hassouna;Barbara Oliveira

  • Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model.

    Hossein Tezval;Olaf Jahn;Cedomir Todorovic;Astrid Sasse

  • Roadmap and standard operating procedures for biobanking and discovery of neurochemical markers in ALS

    Markus Otto;Robert Bowser;Martin Turner;James Berry

  • Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.

    Fernando Rodríguez-Castañeda;Mitcheell Maestre-Martínez;Nicolas Coudevylle;Kalina Dimova

Frequent Co-Authors

Nils Brose
Nils Brose Max Planck Society
Jens Wiltfang
Jens Wiltfang University of Göttingen
Henning Urlaub
Henning Urlaub University of Göttingen
Klaus-Armin Nave
Klaus-Armin Nave Max Planck Society
Wiebke Möbius
Wiebke Möbius Max Planck Society
Hannelore Ehrenreich
Hannelore Ehrenreich Central Institute of Mental Health
Stefan Tenzer
Stefan Tenzer Johannes Gutenberg University of Mainz
Bernhard Schmidt
Bernhard Schmidt University of Göttingen
Andrea Sinz
Andrea Sinz Martin Luther University Halle-Wittenberg
Markus Zweckstetter
Markus Zweckstetter German Center for Neurodegenerative Diseases

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