World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
10075
World Ranking
17118
National Ranking
7054

Overview

John A. Martignetti is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a significant focus on molecular biology and cancer-related studies.

Their recent publications cover a range of topics related to cancer biology, drug delivery systems, and molecular mechanisms in disease contexts. Notable recent papers include:

  • Proteogenomic insights suggest druggable pathways in endometrial carcinoma, 2023, Cancer Cell
  • Treatment-emergent neuroendocrine prostate cancer with a germline BRCA2 mutation: identification of a candidate reversion mutation associated with platinum/PARP-inhibitor resistance, 2021, Molecular Case Studies
  • Pt(II)-PLGA Hybrid in a pH-Responsive Nanoparticle System Targeting Ovarian Cancer, 2023, Pharmaceutics
  • Comparative Serum Analyses Identify Cytokines and Hormones Commonly Dysregulated as Well as Implicated in Promoting Osteolysis in MMP-2-Deficient Mice and Children, 2020, Frontiers in Physiology
  • Engineering and Validation of a Peptide-Stabilized Poly(lactic-co-glycolic) Acid Nanoparticle for Targeted Delivery of a Vascular Disruptive Agent in Cancer Therapy, 2022, Bioconjugate Chemistry

Martignetti's frequent co-authors reflect collaborative work across biomedical and molecular biology research. Their most common collaborators include:

  • Deep Pandya
  • Sylwia A. Dragulska
  • Aneta J. Mieszawska
  • Mina Poursharifi
  • Sabina Świerczek

The scientist has published multiple papers in several key journals, indicating a consistent presence in venues focusing on molecular and cancer biology as well as clinical and pharmaceutical sciences. Some of these frequent publication venues are:

  • The FASEB Journal
  • Molecular Case Studies
  • Pharmaceutics
  • Journal of Clinical Oncology
  • Cancer Research

Martignetti's research interests include specific subfields such as Molecular Biology, Cancer Research, Oncology, Biomaterials, and Pulmonary and Respiratory Medicine. They have contributed notably to topics like:

  • Nanoparticle-Based Drug Delivery
  • RNA Interference and Gene Delivery
  • Cancer Genomics and Diagnostics
  • Endometrial and Cervical Cancer Treatments
  • Graphene and Nanomaterials Applications
  • Soft tissue tumor case studies
  • Sarcoma Diagnosis and Treatment

Their work involves the application of advanced drug delivery technologies and genomic analysis to improve understanding and treatment strategies for various cancers. The portfolio reflects an interdisciplinary approach combining molecular biology, cancer genomics, and nanotechnology to address clinical challenges.

Best Publications

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

    M. S. Chee;A. T. Bankier;S. Beck;R. Bohni

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    Adam Abeshouse;Clement Adebamowo;Sally N. Adebamowo;Rehan Akbani

  • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.

    André Kahles;Kjong-Van Lehmann;Nora C Toussaint;Matthias Hüser

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Pivotal Role of mTOR Signaling in Hepatocellular Carcinoma

    Augusto Villanueva;Derek Y. Chiang;Pippa Newell;Judit Peix

  • KLF6, a candidate tumor suppressor gene mutated in prostate cancer.

    Goutham Narla;Karen E. Heath;Helen L. Reeves;Dan Li

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

    Franz X. Schaub;Varsha Dhankani;Ashton C. Berger;Mihir Trivedi

  • Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium.

    Seri M;Cusano R;Gangarossa S;Caridi G

  • Nonmuscle Myosin Heavy Chain IIA Mutations Define a Spectrum of Autosomal Dominant Macrothrombocytopenias: May-Hegglin Anomaly and Fechtner, Sebastian, Epstein, and Alport-Like Syndromes

    Karen E. Heath;Angel Campos-Barros;Amos Toren;Galit Rozenfeld-Granot

  • Mutation of the matrix metalloproteinase 2 gene ( MMP2 ) causes a multicentric osteolysis and arthritis syndrome

    John A. Martignetti;Aida Al Aqeel;Wafaa Al Sewairi;Christine E. Boumah

  • Proteogenomic Characterization of Endometrial Carcinoma.

    Yongchao Dou;Emily A. Kawaler;Daniel Cui Zhou;Marina A. Gritsenko

  • Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

    Joshua D. Campbell;Joshua D. Campbell;Joshua D. Campbell;Christina Yau;Christina Yau;Reanne Bowlby;Yuexin Liu

  • A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk.

    Goutham Narla;Analisa DiFeo;Helen L. Reeves;Daniel J. Schaid

  • The DNA sequence of the human cytomegalovirus genome.

    Bankier At;Beck S;Bohni R;Brown Cm

Frequent Co-Authors

Goutham Narla
Goutham Narla University of Michigan–Ann Arbor
Scott L. Friedman
Scott L. Friedman Icahn School of Medicine at Mount Sinai
Robert Sebra
Robert Sebra Icahn School of Medicine at Mount Sinai
Robert J. Desnick
Robert J. Desnick Icahn School of Medicine at Mount Sinai
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai
Maciej Wiznerowicz
Maciej Wiznerowicz Poznan University of Medical Sciences
Michael J. Birrer
Michael J. Birrer University of Arkansas for Medical Sciences
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Christina Yau
Christina Yau University of California, San Francisco
Douglas A. Levine
Douglas A. Levine New York University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

A background in Biology or Biochemistry can open doors to a variety of fast-growing fields—especially in healthcare and science. If you’re looking to expand your career options, several online degrees can help you specialize further without stepping away from work or other commitments.

For those aiming for management roles, an accelerated healthcare management degree online enables rapid progression into administrative positions in hospitals or biotech firms. Nursing professionals interested in mental health can consider a fast track mental health nursing program for advanced practice and high-demand roles.

If your passion is nutrition or wellness, you might explore a 2 year nutrition degree online to qualify for entry-level jobs in dietetics and health coaching. For those seeking flexibility and affordability, a cheap online mba healthcare administration is a cost-effective route to leadership positions across healthcare organizations.

These pathways provide the flexibility to study at your own pace, making it easier than ever to gain advanced credentials and broaden your career prospects in science and health.

Best Scientists Citing John A. Martignetti

Trending Scientists