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Molecular Biology

D-Index
66
Citations
14352
World Ranking
1624
National Ranking
127

Geoffrey P. Margison publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Geoffrey P. Margison sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 318 publications — 83rd percentile

83% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

Geoffrey P. Margison D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Geoffrey P. Margison sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 66 D-Index — 48th percentile

48% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Overview

Geoffrey P. Margison is affiliated with the University of Manchester in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with a particular focus on molecular biology at the subfield level.

The scientist's work encompasses key topics including DNA repair mechanisms, DNA and nucleic acid chemistry, epigenetics and DNA methylation, carcinogens and genotoxicity assessment, cancer therapeutics and mechanisms, computational drug discovery methods, and cancer genomics and diagnostics.

Recent publications by Geoffrey P. Margison include the following papers:

  • QSAR and Chemical Read-Across Analysis of 370 Potential MGMT Inactivators to Identify the Structural Features Influencing Inactivation Potency (2023, Pharmaceutics)
  • Mass Spectrometric Analysis of the Active Site Tryptic Peptide of Recombinant O6-Methylguanine-DNA Methyltransferase Following Incubation with Human Colorectal DNA Reveals the Presence of an O6-Alkylguanine Adductome (2023, Chemical Research in Toxicology)
  • The DNA Alkyltransferase Family of DNA Repair Proteins: Common Mechanisms, Diverse Functions (2023, International Journal of Molecular Sciences)
  • Synthesis of oligodeoxyribonucleotides containing a tricyclic thio analogue of O6-methylguanine and their recognition by MGMT and Atl1 (2020, Nucleosides Nucleotides & Nucleic Acids)
  • Abstract 5780: Developing a screen for O6-alkylguanines in human DNA using the damage-specific binding protein, Atl1 (2020, Cancer Research)

Geoffrey P. Margison has frequently collaborated with other researchers, including:

  • David M. Williams
  • Andrew Povey
  • Pattama Senthong
  • Oliver J. Wilkinson
  • Andrew C. Povey

The scientist's work has appeared in varied publication venues, reflecting the interdisciplinary nature of their research:

  • Pharmaceutics
  • Chemical Research in Toxicology
  • International Journal of Molecular Sciences
  • Nucleosides Nucleotides & Nucleic Acids
  • Cancer Research

Best Publications

  • Mechanisms of carcinogenesis induced by alkylating agents.

    Roy Saffhill;Geoffrey P Margison;Peter J O'Connor

  • hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents

    R Brown;G L Hirst;W M Gallagher;A J McIlwrath

  • Are there low-penetrance TP53 Alleles? evidence from childhood adrenocortical tumors.

    Jennifer M. Varley;Gail McGown;Mary Thorncroft;Louise A. James

  • Mechanisms of carcinogenicity/chemotherapy by O6-methylguanine.

    Geoffrey P. Margison;Mauro F. Santibáñez Koref;Andrew C. Povey

  • O6‐alkylguanine‐DNA alkyltransferase: Role in carcinogenesis and chemotherapy

    Geoffrey P. Margison;Mauro F. Santibáñez-Koref

  • Variability and regulation of O6-alkylguanine–DNA alkyltransferase

    Geoffrey P. Margison;Andrew C. Povey;Bernd Kaina;Mauro F. Santibáñez Koref

  • Depletion of O6-alkylguanine-DNA alkyltransferase correlates with potentiation of temozolomide and CCNU toxicity in human tumour cells.

    J. C. Baer;A. A. Freeman;E. S. Newlands;A. J. Watson

  • Equal potency of gammaretroviral and lentiviral SIN vectors for expression of O6-methylguanine–DNA methyltransferase in hematopoietic cells

    Axel Schambach;Jens Bohne;Saurabh Chandra;Elke Will

  • Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli.

    P M Potter;M C Wilkinson;J Fitton;Francis J Carr

  • Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine

    Neil J. Toft;Douglas J. Winton;Jane Kelly;Louise A. Howard

  • Phase II study of SPI-77 (sterically stabilised liposomal cisplatin) in advanced non-small-cell lung cancer

    Shane C White;Paul C Lorigan;Geoffrey P Margison;Jennifer M Margison

  • Lomeguatrib, a Potent Inhibitor of O6-Alkylguanine-DNA-Alkyltransferase: Phase I Safety, Pharmacodynamic, and Pharmacokinetic Trial and Evaluation in Combination with Temozolomide in Patients with Advanced Solid Tumors

    Malcolm R Ranson;Mark R Middleton;John Bridgewater;Siow Ming Lee

  • Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine

    B Hang;B Singer;Geoffrey P Margison;Rhoderick H Elder

  • Alkylpurine–DNA–N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients

    Sameer Agnihotri;Aaron S. Gajadhar;Christian Ternamian;Thierry Gorlia

  • Targeting O6-methylguanine-DNA methyltransferase with specific inhibitors as a strategy in cancer therapy

    Bernd Kaina;Geoffrey P. Margison;Markus Christmann

  • O6-Methylguanine-DNA methyltransferase inactivation and chemotherapy

    Barbara Verbeek;Thomas D. Southgate;David E. Gilham;Geoffrey P. Margison

  • Cloning of the E. coli O6-methylguanine and methylphosphotriester methyltransferase gene using a functional DNA repair assay

    Geoffrey P. Margison;Donald P. Cooper;John Brennand

  • Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene

    John Brennand;Geoffrey P. Margison

  • A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours

    O A Khan;M Gore;Paul C Lorigan;J Stone

  • Expression of Ku70 correlates with survival in carcinoma of the cervix.

    C R Wilson;Susan E Davidson;Geoffrey P Margison;S P Jackson

Frequent Co-Authors

Mark R. Middleton
Mark R. Middleton University of Oxford
Nick Thatcher
Nick Thatcher University of Manchester
Mauro Santibanez-Koref
Mauro Santibanez-Koref Newcastle University
Philip M. Potter
Philip M. Potter St. Jude Children's Research Hospital
Christopher Baum
Christopher Baum Charité - University Medicine Berlin
Ruggero Montesano
Ruggero Montesano International Agency For Research On Cancer
Anthony E. Pegg
Anthony E. Pegg Pennsylvania State University
David A. Williams
David A. Williams Boston Children's Hospital
Anthony Howell
Anthony Howell University of Manchester
Axel Schambach
Axel Schambach Hannover Medical School

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