Philip M. Potter

Overview

Best Publications

• Targeting Oxidative Stress in Embryonal Rhabdomyosarcoma

  Xiang Chen;Elizabeth Stewart;Anang A. Shelat;Chunxu Qu

  317
  Citations

• Mammalian carboxylesterases: from drug targets to protein therapeutics.

  Matthew R. Redinbo;Philip M. Potter

  273
  Citations

• Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme.

  Sompop Bencharit;Christopher L Morton;Yu Xue;Philip M Potter

  252
  Citations

• Hydrolysis of pyrethroids by human and rat tissues: Examination of intestinal, liver and serum carboxylesterases

  J. Allen Crow;Abdolsamad Borazjani;Philip M. Potter;Matthew K. Ross

  243
  Citations

• Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing.

  Liying Fan;Chandraiah Lagisetti;Carol C. Edwards;Thomas R. Webb

  241
  Citations

• Proficient metabolism of irinotecan by a human intestinal carboxylesterase.

  Ruchi Khanna;Christopher L. Morton;Mary K. Danks;Philip M. Potter

  224
  Citations

• Hydrolytic metabolism of pyrethroids by human and other mammalian carboxylesterases.

  Matthew K. Ross;Abdolsamad Borazjani;Carol C. Edwards;Philip M. Potter

  219
  Citations

• Structural insights into CPT-11 activation by mammalian carboxylesterases.

  Sompop Bencharit;Christopher L. Morton;Escher L. Howard-Williams;Mary K. Danks

  216
  Citations

• Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli.

  P M Potter;M C Wilkinson;J Fitton;Francis J Carr

  213
  Citations

• Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene

  Linda C. Harris;Philip M. Potter;Keizo Tano;Susumu Shiota

  208
  Citations

• Crystal structure of human carboxylesterase 1 complexed with the Alzheimer's drug tacrine: from binding promiscuity to selective inhibition.

  Sompop Bencharit;Christopher L Morton;Janice L Hyatt;Peter Kuhn

  201
  Citations

• Identification and Characterization of Novel Benzil (Diphenylethane-1,2-dione) Analogues as Inhibitors of Mammalian Carboxylesterases

  Randy M. Wadkins;Janice L. Hyatt;Xin Wei;Kyoung Jin P. Yoon

  194
  Citations

• Carboxylesterases - Detoxifying Enzymes and Targets for Drug Therapy

  Philip M Potter;Randy M Wadkins

  192
  Citations

• Targeting the DNA repair pathway in Ewing sarcoma

  Elizabeth Stewart;Ross Goshorn;Cori Bradley;Lyra M. Griffiths

  180
  Citations

• Tumor-Targeted Enzyme/Prodrug Therapy Mediates Long-term Disease-Free Survival of Mice Bearing Disseminated Neuroblastoma

  Mary K. Danks;K. Jin Yoon;Rebecca A. Bush;Joanna S. Remack

  166
  Citations

• Carboxylesterases: General detoxifying enzymes.

  M. Jason Hatfield;Robyn A. Umans;Janice L. Hyatt;Carol C. Edwards

  164
  Citations

• Multisite Promiscuity in the Processing of Endogenous Substrates by Human Carboxylesterase 1

  Sompop Bencharit;Carol C. Edwards;Christopher L. Morton;Escher L. Howard-Williams

  155
  Citations

• Human carboxylesterase 1: from drug metabolism to drug discovery.

  M.R. Redinbo;S. Bencharit;P.M. Potter

  154
  Citations

• Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil.

  Christopher D. Fleming;Sompop Bencharit;Carol C. Edwards;Janice L. Hyatt

  153
  Citations

• Comparison of activation of CPT-11 by rabbit and human carboxylesterases for use in enzyme/prodrug therapy.

  Mary K. Danks;Christopher L. Morton;Erik J. Krull;Pamela J. Cheshire

  152
  Citations