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D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
20980
World Ranking
6224
National Ranking
2928

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Matthew R. Redinbo is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, with a significant focus on Medicine. Within these, their work particularly addresses subfields such as Molecular Biology, Pharmacology, Physiology, Infectious Diseases, and Genetics.

The scientist's research topics encompass diverse areas related to microbiology and health. Key topics of their studies include:

  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Diet and metabolism studies
  • Cancer therapeutics and mechanisms
  • Probiotics and Fermented Foods
  • Pharmacological Effects of Natural Compounds
  • Tryptophan and brain disorders

Redinbo's publication record includes contributions to various journals and venues. Frequent publication venues are as follows:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Crystallographica Section A Foundations and Advances
  • Nature Microbiology
  • Gut Microbes

Some of the recent papers authored by Redinbo or involving their contributions include:

  • "Reporting guidelines for human microbiome research: the STORMS checklist," 2021, Nature Medicine
  • "Plant "helper" immune receptors are Ca 2+ -permeable nonselective cation channels," 2021, Science
  • "Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy," 2020, Proceedings of the National Academy of Sciences
  • "Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut," 2023, Nature Microbiology
  • "Gut-Derived Protein-Bound Uremic Toxins," 2020, Toxins

Frequent co-authors collaborating with Redinbo include:

  • William G. Walton
  • Joshua B. Simpson
  • Aadra P. Bhatt
  • Josh J. Sekela
  • Parth B. Jariwala

The scientist has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS) since 2013.

Best Publications

  • Crystal Structures of Human Topoisomerase I in Covalent and Noncovalent Complexes with DNA

    Matthew R. Redinbo;Lance Stewart;Peter Kuhn;James J. Champoux

  • Alleviating cancer drug toxicity by inhibiting a bacterial enzyme

    Bret D. Wallace;Hongwei Wang;Kimberly T. Lane;John E. Scott

  • Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

    Madhukumar Venkatesh;Subhajit Mukherjee;Hongwei Wang;Hao Li

  • The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity

    R. E. Watkins;G. B. Wisely;L. B. Moore;J. L. Collins

  • A model for the mechanism of human topoisomerase I.

    Lance Stewart;Matthew R. Redinbo;Xiayang Qiu;Wim G. J. Hol

  • The role of the microbiome in cancer development and therapy

    Aadra P. Bhatt;Matthew R. Redinbo;Scott J. Bultman

  • Crystal structure of an ancient protein: evolution by conformational epistasis.

    Eric A. Ortlund;Jamie T. Bridgham;Matthew R. Redinbo;Joseph W. Thornton

  • Regulation of CYP3A gene transcription by the pregnane X receptor

    Bryan Goodwin;Matthew R. Redinbo;Steven A. Kliewer

  • Reporting guidelines for human microbiome research: the STORMS checklist

    Chloe Mirzayi;Audrey Renson;Massive Analysis

  • 2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin.

    Ryan E. Watkins;Jodi M. Maglich;Linda B. Moore;G. Bruce Wisely

  • Plant “helper” immune receptors are Ca2+-permeable nonselective cation channels

    Pierre Jacob;Nak Hyun Kim;Feihua Wu;Feihua Wu;Farid El-Kasmi

  • Mammalian carboxylesterases: from drug targets to protein therapeutics.

    Matthew R. Redinbo;Philip M. Potter

  • Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily.

    Gabriel Schaaf;Eric A. Ortlund;Kimberly R. Tyeryar;Carl J. Mousley

  • Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor.

    Ryan E. Watkins;Paula R. Davis-Searles;Paula R. Davis-Searles;Mill H. Lambert;Matthew R. Redinbo

  • Structure and Inhibition of Microbiome β-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity

    Bret D. Wallace;Adam B. Roberts;Rebecca M. Pollet;James D. Ingle

  • Structural basis of heroin and cocaine metabolism by a promiscuous human drug-processing enzyme.

    Sompop Bencharit;Christopher L Morton;Yu Xue;Philip M Potter

  • Structural disorder in the complex of human pregnane x receptor and the macrolide antibiotic rifampicin

    Jill E. Chrencik;Jillian Orans;Linda B. Moore;Yu Xue

  • Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole.

    H. Huang;H. Wang;M. Sinz;M. Zoeckler

  • Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7

    Michael J. Miley;Agnieszka K. Zielinska;Jeffrey E. Keenan;Stacie M. Bratton

  • An Atlas of β-Glucuronidases in the Human Intestinal Microbiome.

    Rebecca M. Pollet;Emma H. D'Agostino;William G. Walton;Yongmei Xu

Frequent Co-Authors

Philip M. Potter
Philip M. Potter St. Jude Children's Research Hospital
Lance Stewart
Lance Stewart University of Washington
Steven A. Kliewer
Steven A. Kliewer The University of Texas Southwestern Medical Center
Robert Tarran
Robert Tarran University of North Carolina at Chapel Hill
Wim G. J. Hol
Wim G. J. Hol University of Washington
Yves Pommier
Yves Pommier National Institutes of Health
James J. Champoux
James J. Champoux University of Washington
Jian Jin
Jian Jin Icahn School of Medicine at Mount Sinai
Todd O. Yeates
Todd O. Yeates University of California, Los Angeles
Sean Ekins
Sean Ekins University of Arizona

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