2014 - Fellow of John Simon Guggenheim Memorial Foundation
2006 - Fellow of Alfred P. Sloan Foundation
Joseph W. Thornton focuses on Evolutionary biology, Phylogenetics, Molecular evolution, Receptor and Phylogenetic tree. In general Evolutionary biology, his work in Function is often linked to Functional synthesis linking many areas of study. His research integrates issues of Gene duplication, Peptide sequence, Sequence alignment and Vertebrate in his study of Phylogenetics.
He works mostly in the field of Molecular evolution, limiting it down to concerns involving Protein structure and, occasionally, Epistasis. His work carried out in the field of Receptor brings together such families of science as Endocrinology and Steroidogenic factor 1. His work on Nuclear receptor and Genome as part of general Genetics research is frequently linked to GPR18, thereby connecting diverse disciplines of science.
Joseph W. Thornton mainly investigates Evolutionary biology, Genetics, Gene, Molecular evolution and Phylogenetics. His research in Evolutionary biology intersects with topics in Epistasis, Sequence, Genomics and Phylogenetic tree. His Genetics study frequently draws parallels with other fields, such as Protein structure.
The concepts of his Protein structure study are interwoven with issues in Mutation, Structural biology and Sequence alignment. His Transcription factor research focuses on Receptor and how it connects with Hormone, Endocrinology and Gene expression. His studies in Multiprotein complex integrate themes in fields like Mutagenesis and Molecular machine.
His primary areas of investigation include Evolutionary biology, Phylogenetic tree, Gene, Contingency and Sequence. His Evolutionary biology research includes elements of Homeobox, Phylogenetics, Molecular evolution, Drosophila embryogenesis and Allosteric regulation. His studies deal with areas such as Lineage and Genetic variation as well as Molecular evolution.
His Allosteric regulation research includes themes of Gene duplication, Protein structure, Protein subunit and Cooperativity. Joseph W. Thornton has included themes like Positive selection and Fixation in his Phylogenetic tree study. His research on Gene concerns the broader Genetics.
The scientist’s investigation covers issues in Evolutionary biology, Gene, Allosteric regulation, Molecular evolution and Phylogenetic tree. The Evolutionary biology study combines topics in areas such as Protein structure, Heterotetramer and Phylogenetics. His Gene research incorporates elements of Biophysics, Function and Structural bioinformatics.
His biological study spans a wide range of topics, including Cooperativity, Natural selection, Protein subunit, Negative selection and Gene duplication. His Molecular evolution study combines topics from a wide range of disciplines, such as Positive selection, Fixation, Population genetics and Human evolutionary genetics. His Phylogenetic tree research is multidisciplinary, incorporating elements of Homeobox, Transcription factor, Evolutionary developmental biology and Drosophila embryogenesis.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Resurrecting the Ancestral Steroid Receptor: Ancient Origin of Estrogen Signaling
Joseph W. Thornton;Joseph W. Thornton;Eleanor Need;Eleanor Need;David P Crews;David P Crews.
Science (2003)
Evolution of vertebrate steroid receptors from an ancestral estrogen receptor by ligand exploitation and serial genome expansions
Joseph W. Thornton.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Evolution of Hormone-Receptor Complexity by Molecular Exploitation
Jamie T. Bridgham;Sean M. Carroll;Joseph W. Thornton.
Science (2006)
Performance of maximum parsimony and likelihood phylogenetics when evolution is heterogeneous
Bryan Kolaczkowski;Joseph W. Thornton.
Nature (2004)
Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts.
Mary Beth Hawkins;Joseph W. Thornton;David P Crews;James K. Skipper.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Crystal structure of an ancient protein: evolution by conformational epistasis.
Eric A. Ortlund;Jamie T. Bridgham;Matthew R. Redinbo;Joseph W. Thornton.
Science (2007)
Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1.
Irina N. Krylova;Elena P. Sablin;Jamie Moore;Robert X. Xu.
Cell (2005)
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution
Jamie T. Bridgham;Eric A. Ortlund;Joseph W. Thornton.
Nature (2009)
Resurrecting ancient genes: experimental analysis of extinct molecules
Joseph W. Thornton.
Nature Reviews Genetics (2004)
Mechanistic approaches to the study of evolution: The functional synthesis
Antony M. Dean;Joseph W. Thornton.
Nature Reviews Genetics (2007)
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