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Vytas A. Bankaitis

Vytas A. Bankaitis

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
15817
World Ranking
1124
National Ranking
582

Overview

Vytas A. Bankaitis is affiliated with Texas A&M University in the United States and conducts research primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work emphasizes Molecular Biology, Cell Biology, Genetics, Epidemiology, and Immunology as key subfields of study.

The scientist's recent publications cover a range of topics related to lipid metabolism, cellular transport, and pancreatic function. Notable papers include:

  • "Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase," 2020, published in The Journal of Cell Biology
  • "Lipid transfer proteins and instructive regulation of lipid kinase activities: Implications for inositol lipid signaling and disease," 2020, published in Advances in Biological Regulation
  • "Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration," 2022, published in Cell Reports
  • "Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction," 2023, published in Nature Communications
  • "A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins," 2020, published in eLife

Their research topics cover diverse areas including:

  • Cellular transport and secretion
  • Trypanosoma species research and implications
  • Endoplasmic Reticulum Stress and Disease
  • Lipid Membrane Structure and Behavior
  • Pancreatic function and diabetes
  • Nuclear Structure and Function
  • Toxin Mechanisms and Immunotoxins

Frequent co-authors contributing to joint research projects include:

  • Carl J. Mousley
  • Ashutosh Tripathi
  • Gabriel Schaaf
  • Aaron H. Nile
  • Danish Khan

The primary publication venues where this scientist has disseminated work are:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Advances in Biological Regulation
  • Journal of Biological Chemistry
  • eLife

The body of work indicates involvement with biochemical pathways related to lipid signaling and cell biology mechanisms spanning from fundamental molecular functions to disease implications, especially focusing on diabetes and cellular transport processes.

Best Publications

  • An essential role for a phospholipid transfer protein in yeast Golgi function.

    Vytas A. Bankaitis;Jacqueline R. Aitken;Ann E. Cleves;William Dowhan

  • Isolation of yeast mutants defective in protein targeting to the vacuole

    Vytas A. Bankaitis;Lianna M. Johnson;Scott D. Emr

  • The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex.

    Vytas A. Bankaitis;David E. Malehorn;Scott D. Emr;Robert Greene

  • Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis

    Patrick Brennwald;Brian Kearns;Kathy Champion;Sirkka Keränen

  • Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein.

    Ann E. Cleves;Todd P. McGee;Eric A. Whitters;Kathleen M. Champlon

  • The antifolding activity of SecB promotes the export of the E. coli maltose-binding protein

    David N. Collier;Vytas A. Bankaitis;Judith B. Weiss;Philip J. Bassford

  • Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease

    Lianna M. Johnson;Vytas A. Bankaitis;Scott D. Emr

  • Essential role for diacylglycerol in protein transport from the yeast Golgi complex

    Brian G. Kearns;Todd P. McGee;Peter Mayinger;Alma Gedvilaite

  • Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol- transfer protein

    Bingdong Sha;Scott E. Phillips;Vytas A. Bankaitis;Ming Luo

  • Activation of the Phosphatidylinositol 3-Kinase Vps34 by a G Protein α Subunit at the Endosome

    Janna E. Slessareva;Sheri M. Routt;Brenda Temple;Vytas A. Bankaitis

  • Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function.

    Ann E. Cleves;Peter J. Novick;Vytas A. Bankaitis

  • Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily.

    Gabriel Schaaf;Eric A. Ortlund;Kimberly R. Tyeryar;Carl J. Mousley

  • Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex

    Xinmin Li;Marcos P. Rivas;Min Fang;Jennifer Marchena

  • A Sec14p-nodulin domain phosphatidylinositol transfer protein polarizes membrane growth of Arabidopsis thaliana root hairs

    Patrick Vincent;Michael Chua;Fabien Nogue;Ashley Fairbrother

  • Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

    Anna Y. Lee;Robert P. St.Onge;Michael J. Proctor;Iain M. Wallace

  • A role for phosphatidylinositol transfer protein in secretory vesicle formation

    Masato Ohashi;Klaas Jan de Vries;Rainer Frank;Gerry Snoek

  • Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis.

    M. Fang;B. G. Kearns;A. Gedvilaite;S. Kagiwada

  • A phosphatidylinositol transfer protein controls the phosphatidylcholine content of yeast Golgi membranes

    Todd P. McGee;Henry B. Skinner;Eric A. Whitters;Susan A. Henry

  • The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling

    Vytas A. Bankaitis;Carl J. Mousley;Gabriel Schaaf

  • Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

    A. Y. Lee;R. P. St.Onge;M. J. Proctor;I. M. Wallace

Frequent Co-Authors

Guri Giaever
Guri Giaever University of British Columbia
Ronald W. Davis
Ronald W. Davis Stanford University
Corey Nislow
Corey Nislow University of British Columbia
Maya Schuldiner
Maya Schuldiner Weizmann Institute of Science
Zhigang Xie
Zhigang Xie Chinese Academy of Sciences
Scott D. Emr
Scott D. Emr Cornell University
Marc Boutry
Marc Boutry Université Catholique de Louvain
Grant W. Brown
Grant W. Brown University of Toronto
Gary D. Bader
Gary D. Bader University of Toronto
Brian K. Kennedy
Brian K. Kennedy National University of Singapore

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