Her main research concerns Cell biology, Biochemistry, Oxysterol-binding protein, OSBP and Molecular biology. Her research in Cell biology intersects with topics in Endocytic cycle, Epithelial polarity and Cell membrane. She specializes in Oxysterol-binding protein, namely Oxysterol binding.
Her Oxysterol binding research includes themes of Lipogenesis, Sterol binding, Pleckstrin homology domain and Downregulation and upregulation. Her OSBP research is multidisciplinary, relying on both Cell culture, Gene knockdown, Poliovirus, PI4KB and Coxsackievirus. Her biological study spans a wide range of topics, including Complementary DNA, Palmitoyl protein thioesterase, Cystovirus and Infantile neuronal ceroid lipofuscinosis.
Her scientific interests lie mostly in Cell biology, Biochemistry, Internal medicine, OSBP and Endocrinology. Her Oxysterol-binding protein, Endoplasmic reticulum, Oxysterol binding, Endosome and Golgi apparatus study are her primary interests in Cell biology. Vesa M. Olkkonen has researched Oxysterol-binding protein in several fields, including Liver X receptor, Oxysterol and Lipid droplet.
Her studies in Endoplasmic reticulum integrate themes in fields like Calcium, Phosphatidylserine, Molecular biology, Membrane and Organelle. The study incorporates disciplines such as Endocytic cycle and Late endosome in addition to Endosome. Vesa M. Olkkonen interconnects Membrane contact site, Sterol transport, Pleckstrin homology domain and Protein family in the investigation of issues within OSBP.
Vesa M. Olkkonen mainly focuses on Cell biology, OSBP, Endocrinology, Internal medicine and Endoplasmic reticulum. Her Cell biology research is multidisciplinary, incorporating elements of Cell, Lipid metabolism and Membrane. Her OSBP research integrates issues from CD34, Myeloid leukemia, Intracellular, Lipid droplet and Gq alpha subunit.
Her research investigates the connection between Endocrinology and topics such as Hepatocyte that intersect with problems in Fatty liver. Her work on Golgi apparatus as part of general Endoplasmic reticulum study is frequently linked to Förster resonance energy transfer, therefore connecting diverse disciplines of science. Her Oxysterol-binding protein study incorporates themes from Cell signaling and Endosome.
Cell biology, Endoplasmic reticulum, Golgi apparatus, Drug development and Lipid droplet are her primary areas of study. Her research integrates issues of Lipid metabolism, Glucose uptake and Adipocyte in her study of Cell biology. Her study in the field of Oxysterol binding also crosses realms of Ceramide Transfer Protein and Förster resonance energy transfer.
Her studies deal with areas such as In vitro, Signal transducing adaptor protein, Secretion, Phosphatase and Kinase as well as Golgi apparatus. Her Lipid droplet study frequently draws connections to other fields, such as OSBP. Her work carried out in the field of Oxysterol-binding protein brings together such families of science as Endocytic cycle, Filipin, Endosome and Cytosol.
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The Rab GTPase family
Harald Stenmark;Vesa M Olkkonen.
Genome Biology (2001)
Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism
Sabine D. Jordan;Markus Krüger;Diana M. Willmes;Nora Redemann.
Nature Cell Biology (2011)
Activation of endosomal dynein motors by stepwise assembly of Rab7–RILP–p150Glued, ORP1L, and the receptor βlll spectrin
Marie Johansson;Nuno Rocha;Wilbert Zwart;Ingrid Jordens.
Journal of Cell Biology (2007)
Role of Rab GTPases in membrane traffic.
Vesa M. Olkkonen;Harald Alfred Stenmark.
International Review of Cytology-a Survey of Cell Biology (1997)
Dissecting the role of the Golgi complex and lipid rafts in biosynthetic transport of cholesterol to the cell surface
Sanna Heino;Sari Lusa;Pentti Somerharju;Christian Ehnholm.
Proceedings of the National Academy of Sciences of the United States of America (2000)
The impact of phospholipid transfer protein (PLTP) on HDL metabolism.
Jarkko Huuskonen;Vesa M. Olkkonen;Matti Jauhiainen;Christian Ehnholm.
Atherosclerosis (2001)
The oxysterol-binding protein homologue ORP1L interacts with Rab7 and alters functional properties of late endocytic compartments
Marie Johansson;Markku Lehto;Kimmo Tanhuanpää;Timothy L. Cover.
Molecular Biology of the Cell (2005)
The OSBP-related protein family in humans
Markku Lehto;Saara Laitinen;Giulia Chinetti;Marie Johansson.
Journal of Lipid Research (2001)
Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis.
E. Hellsten;J. Vesa;V. M. Olkkonen;A. Jalanko.
The EMBO Journal (1996)
Biosynthesis and Intracellular Targeting of the CLN3 Protein Defective in Batten Disease
Irma Järvelä;Markku Sainio;Terhi Rantamäki;Vesa M. Olkkonen.
Human Molecular Genetics (1998)
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