Anu Jalanko

Overview

Best Publications

• Molecular genetics of the Finnish disease heritage.

  Leena Peltonen;Anu Jalanko;Teppo Varilo

  680
  Citations

• Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers.

  Nina Mars;Jukka T Koskela;Pietari Ripatti;Tuomo T J Kiiskinen

  527
  Citations

• Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice

  Henna Tyynismaa;Katja Peltola Mjosund;Sjoerd Wanrooij;Ilse Lappalainen

  377
  Citations

• Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

  Henna Tyynismaa;Hiroshi Sembongi;Monika Bokori-Brown;Caroline Granycome

  298
  Citations

• Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis.

  E. Hellsten;J. Vesa;V. M. Olkkonen;A. Jalanko

  254
  Citations

• Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential

  Aija Kyttälä;Roksana Moraghebi;Cristina Valensisi;Johannes Kettunen

  249
  Citations

• Cloning and Characterization of Human Placental Catechol--Methyltransferase cDNA

  Kenneth Lundstr;Marjo Salminen;Anu Jalanko;Raija Savolainen

  240
  Citations

• Biosynthesis and Intracellular Targeting of the CLN3 Protein Defective in Batten Disease

  Irma Järvelä;Markku Sainio;Terhi Rantamäki;Vesa M. Olkkonen

  225
  Citations

• Interconnections of CLN3, Hook1 and Rab proteins link Batten disease to defects in the endocytic pathway

  Kaisu Luiro;Kristiina Yliannala;Laura Ahtiainen;Heidi Maunu

  187
  Citations

• CLN3 protein is targeted to neuronal synapses but excluded from synaptic vesicles: new clues to Batten disease

  Kaisu Luiro;Outi Kopra;Maarit Lehtovirta;Anu Jalanko

  179
  Citations

• Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein

  Juha Isosomppi;Jouni Vesa;Anu Jalanko;Leena Peltonen

  167
  Citations

• Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3.

  Jouni Vesa;Mark H. Chin;Kathrin Oelgeschläger;Juha Isosomppi

  167
  Citations

• The neuronal ceroid lipofuscinosis CLN8 membrane protein is a resident of the endoplasmic reticulum.

  Liina Lonka;Aija Kyttälä;Susanna Ranta;Anu Jalanko

  164
  Citations

• Defective Intracellular Transport of CLN3 is the Molecular Basis of Batten Disease (JNCL)

  Irma Järvelä;Maarit Lehtovirta;Ritva Tikkanen;Aija Kyttälä

  149
  Citations

• Genetic architecture of human plasma lipidome and its link to cardiovascular disease

  Rubina Tabassum;Joel T Rämö;Pietari Ripatti;Jukka T Koskela

  145
  Citations

• Palmitoyl protein thioesterase (PPT) localizes into synaptosomes and synaptic vesicles in neurons: implications for infantile neuronal ceroid lipofuscinosis (INCL)

  Maarit Lehtovirta;Aija Kyttälä;Eeva-Liisa Eskelinen;Michael Hess

  144
  Citations

• Cell biology and function of neuronal ceroid lipofuscinosis-related proteins.

  Katrin Kollmann;Kristiina Uusi-Rauva;Enzo Scifo;Jaana Tyynelä

  142
  Citations

• Mice with Ppt1Deltaex4 mutation replicate the INCL phenotype and show an inflammation-associated loss of interneurons

  Anu Jalanko;Jouni Vesa;Tuula Manninen;Carina von Schantz

  127
  Citations

• The role of polygenic risk and susceptibility genes in breast cancer over the course of life.

  Nina Mars;Elisabeth Widén;Sini Kerminen;Tuomo Meretoja

  126
  Citations

• Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells

  Erik L. Bao;Satish K. Nandakumar;Satish K. Nandakumar;Satish K. Nandakumar;Xiaotian Liao;Xiaotian Liao;Xiaotian Liao;Alexander G. Bick

  123
  Citations