David A. Pearce spends much of his time researching Cell biology, Epithelial sodium channel, Endocrinology, Internal medicine and SGK1. David A. Pearce interconnects Regulator, Cell membrane and Cytosol in the investigation of issues within Cell biology. His Epithelial sodium channel study integrates concerns from other disciplines, such as Aldosterone, Homeostasis, Xenopus, Reabsorption and Biochemistry.
His Vacuole, Saccharomyces cerevisiae and Batten disease study, which is part of a larger body of work in Biochemistry, is frequently linked to CLN3, bridging the gap between disciplines. His study looks at the intersection of Endocrinology and topics like Receptor with Pharmacology and Signal transduction. His SGK1 research includes elements of Immediate early protein, Ubiquitin ligase, Sodium channel and Protein kinase A.
David A. Pearce mainly investigates Batten disease, Internal medicine, Ecology, Endocrinology and CLN3. His Batten disease research is multidisciplinary, relying on both Neuronal ceroid lipofuscinosis, Neuroscience and Neurodegeneration. His study in Mineralocorticoid receptor and Kidney is carried out as part of his studies in Internal medicine.
In the field of Ecology, his study on Biodiversity, Biogeography, Arctic and Community structure overlaps with subjects such as Biological dispersal. His Endocrinology research is multidisciplinary, incorporating elements of Glutamate receptor, Receptor, Epithelial sodium channel and Cell biology. His study in Epithelial sodium channel is interdisciplinary in nature, drawing from both Immediate early protein, Ubiquitin ligase and Homeostasis.
His scientific interests lie mostly in Ecology, Bacteria, Biogeography, Arctic and Batten disease. His Environmental change, Biodiversity and Ecosystem study in the realm of Ecology interacts with subjects such as Biological dispersal. His Bacteria research incorporates themes from Botany, Genome and Microbiology.
His Microbiology research focuses on Planococcus Bacteria and how it connects with Phylogenetics, Soil microbiology and Genotype. He focuses mostly in the field of Arctic, narrowing it down to topics relating to Community structure and, in certain cases, Generalist and specialist species and Soil water. David A. Pearce merges Batten disease with CLN3 in his study.
His main research concerns Bacteria, Strain, Ecology, 16S ribosomal RNA and Biogeography. The concepts of his Bacteria study are interwoven with issues in Genome, Botany, Biofertilizer and Algal mat. His research in Ecology is mostly concerned with Biodiversity.
His Biodiversity study combines topics from a wide range of disciplines, such as Marine ecosystem and Polar front. In his study, which falls under the umbrella issue of Biogeography, Microbiome, Environmental change, Taxon, Habitat and Temperate climate is strongly linked to Arctic. David A. Pearce regularly links together related areas like Biochemistry in his Microbiology studies.
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Epithelial sodium channel regulated by aldosterone-induced protein sgk.
Sei-yu Chen;Aditi Bhargava;Luca Mastroberardino;Onno C. Meijer.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na+ channel cell surface expression
Christophe Debonneville;Christophe Debonneville;Sandra Y. Flores;Sandra Y. Flores;Elena Kamynina;Pamela J. Plant.
The EMBO Journal (2001)
Mineralocorticoid and glucocorticoid receptor activities distinguished by nonreceptor factors at a composite response element
David Pearce;Keith R. Yamamoto.
Science (1993)
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.
Johannes Loffing;Marija Zecevic;Eric Féraille;Brigitte Kaissling.
American Journal of Physiology-renal Physiology (2001)
A multi-decade record of high-quality fCO2 data in version 3 of the Surface Ocean CO2 Atlas (SOCAT)
Dorothee C. E. Bakker;Benjamin Pfeil;Benjamin Pfeil;Camilla S. Landa;Camilla S. Landa;Nicolas Metzl.
Earth System Science Data (2016)
Subcellular localization of mineralocorticoid receptors in living cells: Effects of receptor agonists and antagonists
Géza Fejes-Tóth;David Pearce;Anikó Náray-Fejes-Tóth.
Proceedings of the National Academy of Sciences of the United States of America (1998)
Reelin signaling is impaired in autism.
S. Hossein Fatemi;Anne V. Snow;Joel M. Stary;Mohsen Araghi-Niknam.
Biological Psychiatry (2005)
A Common Motif within the Negative Regulatory Regions of Multiple Factors Inhibits Their Transcriptional Synergy
Jorge A. Iñiguez-Lluhí;David Pearce.
Molecular and Cellular Biology (2000)
Patterns of bacterial diversity across a range of Antarctic terrestrial habitats.
Etienne Yergeau;Kevin K. Newsham;David A. Pearce;George A. Kowalchuk.
Environmental Microbiology (2007)
Multiple corticosteroid receptors in a teleost fish: distinct sequences, expression patterns, and transcriptional activities.
Anna K. Greenwood;Paul C. Butler;Richard B. White;Ulrike DeMarco.
Endocrinology (2003)
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