Jonathan D. Cooper

Best Publications

• mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

  Michela Palmieri;Rituraj Pal;Hemanth R. Nelvagal;Parisa Lotfi

  451
  Citations

• Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion.

  Jonathan D. Cooper;Ahmad Salehi;Jean-Dominique Delcroix;Charles L. Howe

  397
  Citations

• Afferent and efferent connections of the laterodorsal tegmental nucleus in the rat.

  J. Cornwall;J.D. Cooper;O.T. Phillipson

  342
  Citations

• Inactivation of bcl-2 Results in Progressive Degeneration of Motoneurons, Sympathetic and Sensory Neurons during Early Postnatal Development

  T.M Michaelidis;M Sendtner;J.D Cooper;M.S Airaksinen

  341
  Citations

• Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

  Jacqueline C. Mitchell;Philip McGoldrick;Caroline Vance;Tibor Hortobagyi

  298
  Citations

• Correction: Corrigendum: mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases

  Michela Palmieri;Rituraj Pal;Hemanth R. Nelvagal;Parisa Lotfi

  278
  Citations

• Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.

  Tracy T. Yeo;Jane Chua-Couzens;Larry L. Butcher;Dale E. Bredesen

  270
  Citations

• Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat hippocampus

  M da Penha Berzaghi;J Cooper;E Castren;F Zafra

  251
  Citations

• Targeted Disruption of the Cln3 Gene Provides a Mouse Model for Batten Disease

  Hannah M. Mitchison;David J. Bernard;Nicholas D.E. Greene;Jonathan D. Cooper

  242
  Citations

• The relative abundance of birds on set-aside and neighbouring fields in summer

  Ian G. Henderson;Jonathan Cooper;Robert J. Fuller;Juliet Vickery

  207
  Citations

• Regional and cellular neuropathology in the palmitoyl protein thioesterase-1 null mutant mouse model of infantile neuronal ceroid lipofuscinosis

  Ellen Bible;Praveena Gupta;Sandra L. Hofmann;Jonathan D. Cooper

  205
  Citations

• Successive neuron loss in the thalamus and cortex in a mouse model of infantile neuronal ceroid lipofuscinosis

  Catherine Kielar;Lucy Maddox;Ellen Bible;Charlie C Pontikis

  187
  Citations

• Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB

  Fiona L. Wilkinson;Rebecca J. Holley;Kia J. Langford-Smith;Soumya Badrinath

  187
  Citations

• Late onset neurodegeneration in the Cln3 -/- mouse model of juvenile neuronal ceroid lipofuscinosis is preceded by low level glial activation

  Charlie C. Pontikis;Claire V. Cella;Nisha Parihar;Ming J. Lim

  184
  Citations

• Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3

  M. V. Sofroniew;Jonathan Cooper;C. N. Svendsen;P. Crossman

  182
  Citations

• Intraventricular enzyme replacement improves disease phenotypes in a mouse model of late infantile neuronal ceroid lipofuscinosis

  Michael Chang;Jonathan D Cooper;David E Sleat;David E Sleat;Seng H Cheng

  181
  Citations

• High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease.

  Michael R. Pears;Jonathan D. Cooper;Hannah M. Mitchison;Russell J. Mortishire-Smith

  181
  Citations

• Projections to the rostral reticular thalamic nucleus in the rat.

  J. Cornwall;J. D. Cooper;O. T. Phillipson

  179
  Citations

• Clinical challenges and future therapeutic approaches for neuronal ceroid lipofuscinosis.

  Sara E Mole;Glenn Anderson;Heather A Band;Samuel F Berkovic

  177
  Citations

• Targeted disruption of the Cln3 gene provides a mouse model for Batten disease (vol 6, pg 321, 1999)

  HM Mitchison;DJ Bernard;Nde Greene;JD Cooper

  5
  Citations