John J. Hopwood

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Best Publications

• Cord-blood transplants from unrelated donors in patients with Hurler's syndrome.

  Susan L. Staba;Maria L. Escolar;Michele Poe;Young Kim

  571
  Citations

• Anticoagulant activity of heparin: Separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin

  Magnus Höök;Ingemar Björk;John Hopwood;Ulf Lindahl

  539
  Citations

• Structure of a human lysosomal sulfatase.

  Charles S Bond;Peter R Clements;Samantha J Ashby;Charles A Collyer

  359
  Citations

• Hunter syndrome: isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA.

  P J Wilson;C P Morris;D S Anson;T Occhiodoro

  323
  Citations

• Enzyme replacement therapy in mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)

  Paul Harmatz;Chester B Whitley;Lewis Waber;Ray Pais

  321
  Citations

• Molecular genetics of muccpolysaccharidosis type I: Diagnostic, clinical, and biological implications

  H S Scott;S Bunge;A Gal;L A Clarke

  252
  Citations

• The mucopolysaccharidoses. Diagnosis, molecular genetics and treatment.

  J J Hopwood;C P Morris

  247
  Citations

• A mouse model for mucopolysaccharidosis type III A (Sanfilippo syndrome)

  Mantu Bhaumik;Vivienne J. Muller;Tina Rozaklis;Johnson Linda

  247
  Citations

• Molecular genetics of mucopolysaccharidosis type IIIA and IIIB: Diagnostic, clinical, and biological implications.

  Gouri Yogalingam;John J. Hopwood

  234
  Citations

• Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-L-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation.

  Kim M. Keeling;Doug A. Brooks;John J. Hopwood;Peining Li

  214
  Citations

• Direct Comparison of Measures of Endurance, Mobility, and Joint Function During Enzyme-Replacement Therapy of Mucopolysaccharidosis VI (Maroteaux-Lamy Syndrome): Results After 48 Weeks in a Phase 2 Open-Label Clinical Study of Recombinant Human N-Acetylgalactosamine 4-Sulfatase

  Paul Harmatz;David Ketteridge;Roberto Giugliani;Natalie Guffon

  206
  Citations

• Newborn screening for lysosomal storage disorders

  Peter J. Meikle;Dallas J. Grasby;Caroline J. Dean;Debbie L. Lang

  204
  Citations

• A strategy for rapid sequencing of heparan sulfate and heparin saccharides

  Jeremy E. Turnbull;John J. Hopwood;John T. Gallagher

  204
  Citations

• A fluorometric assay using 4-methylumbelliferyl α-l-iduronide for the estimation of α-l-iduronidase activity and the detection of Hurler and Scheie syndromes

  John J. Hopwood;Vivienne Muller;Alan Smithson;Neil Baggett

  201
  Citations

• Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes

  Alessandro Fraldi;Kim Hemsley;Allison Crawley;Alessia Lombardi

  198
  Citations

• Molecular basis of mucopolysaccharidosis type II: mutations in the iduronate-2-sulphatase gene.

  J. J. Hopwood;S. Bunge;C. P. Morris;P. J. Wilson

  190
  Citations

• Long-term follow-up of endurance and safety outcomes during enzyme replacement therapy for mucopolysaccharidosis VI: Final results of three clinical studies of recombinant human N-acetylgalactosamine 4-sulfatase

  Paul Harmatz;Roberto Giugliani;Ida Vanessa Ida;Nathalie Guffon

  185
  Citations

• Human alpha-L-iduronidase: cDNA isolation and expression.

  H S Scott;D S Anson;A M Orsborn;P V Nelson

  174
  Citations

• Cloning of the sulphamidase gene and identification of mutations in Sanfilippo A syndrome

  H. S. Scott;L. Blanch;Xiao-Hui Guo;C. Freeman

  171
  Citations

• Epidemiology of lysosomal storage diseases: an overview

  Maria Fuller;Peter J Meikle;John J Hopwood

  169
  Citations