World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
108
Citations
61304
World Ranking
569
National Ranking
322

Overview

Michael V. Sofroniew is affiliated with the University of California, Los Angeles, in the United States. Their research primarily spans neuroscience, biochemistry, genetics and molecular biology, and medicine, with a focus on several subfields including neurology, molecular biology, cellular and molecular neuroscience, immunology, and developmental neuroscience.

The main topics covered in their work include:

  • Neuroinflammation and neurodegeneration mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Nerve injury and regeneration
  • Immune cells in cancer
  • Single-cell and spatial transcriptomics
  • RNA regulation and disease
  • Barrier structure and function studies

Recent publications by Michael V. Sofroniew demonstrate a consistent focus on astrocyte biology, neuroinflammation, and central nervous system (CNS) immunology. These publications include:

  • "Reactive astrocyte nomenclature, definitions, and future directions," 2021, Nature Neuroscience
  • "Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity," 2020, Trends in Immunology
  • "Astrocytes in human central nervous system diseases: a frontier for new therapies," 2023, Signal Transduction and Targeted Therapy
  • "Divergent transcriptional regulation of astrocyte reactivity across disorders," 2022, Nature
  • "Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin," 2022, Nature Communications

Michael V. Sofroniew frequently publishes in well-regarded scientific venues. The most common publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Neuroscience
  • Nature
  • Cell and Tissue Research

The scientist collaborates regularly with several coauthors, indicating sustained teamwork and complementary research interests. Frequent coauthors include:

  • Yan Ao
  • Riki Kawaguchi
  • Timothy M. O'Shea
  • Alexander M. Bernstein
  • Shinong Wang

Best Publications

  • Astrocytes: biology and pathology

    Michael V. Sofroniew;Harry V. Vinters

  • Molecular dissection of reactive astrogliosis and glial scar formation.

    Michael V. Sofroniew

  • Reactive astrocyte nomenclature, definitions, and future directions

    Carole Escartin;Elena Galea;András Lakatos;James P. O’Callaghan

  • Reactive astrocytes protect tissue and preserve function after spinal cord injury.

    Jill R. Faulkner;Julia E. Herrmann;Michael J. Woo;Keith E. Tansey

  • Astrocyte scar formation aids central nervous system axon regeneration

    Mark A. Anderson;Joshua E. Burda;Yilong Ren;Yan Ao

  • Nerve growth factor signaling, neuroprotection, and neural repair

    Michael V Sofroniew;Charles L Howe;William C Mobley

  • Reactive gliosis and the multicellular response to CNS damage and disease.

    Joshua E. Burda;Michael V. Sofroniew

  • Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice

    Toby G Bush;Narman Puvanachandra;Catherine H Horner;Anabella Polito

  • Diversity of astrocyte functions and phenotypes in neural circuits

    Baljit S Khakh;Michael V Sofroniew

  • Astrocyte barriers to neurotoxic inflammation

    Michael V. Sofroniew

  • Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

    Michael D. Saxe;Fortunato Battaglia;Jing Wen Wang;Gael Malleret

  • GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

    A Denise R Garcia;Ngan B Doan;Tetsuya Imura;Toby G Bush

  • STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury

    Julia E. Herrmann;Tetsuya Imura;Bingbing Song;Jingwei Qi

  • Glial scar borders are formed by newly proliferated, elongated astrocytes that interact to corral inflammatory and fibrotic cells via STAT3-dependent mechanisms after spinal cord injury.

    Ina B. Wanner;Mark A. Anderson;Bingbing Song;Jaclynn Levine

  • Reactive Astrocytes in Neural Repair and Protection

    Michael V. Sofroniew

  • Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene.

    N M van der Lugt;J Domen;K Linders;M van Roon

  • Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury.

    Gregoire Courtine;Bingbing Song;Roland R Roy;Hui Zhong

  • Transformation of nonfunctional spinal circuits into functional states after the loss of brain input.

    Grégoire Courtine;Yury Gerasimenko;Rubia van den Brand;Aileen Yew

  • Astrocytes: a central element in neurological diseases

    Milos Pekny;Milos Pekny;Milos Pekny;Marcela Pekna;Marcela Pekna;Marcela Pekna;Albee Messing;Christian Steinhäuser

  • Astrocyte roles in traumatic brain injury.

    Joshua E. Burda;Alexander M. Bernstein;Michael V. Sofroniew

Frequent Co-Authors

Timothy J. Deming
Timothy J. Deming University of California, Los Angeles
Baljit S. Khakh
Baljit S. Khakh University of California, Los Angeles
Ole Isacson
Ole Isacson Harvard University
Alexei Verkhratsky
Alexei Verkhratsky University of Manchester
Milos Pekny
Milos Pekny University of Gothenburg
Marcela Pekna
Marcela Pekna University of Gothenburg
Daniel H. Geschwind
Daniel H. Geschwind University of California, Los Angeles
Tor C. Savidge
Tor C. Savidge Baylor College of Medicine
Grégoire Courtine
Grégoire Courtine École Polytechnique Fédérale de Lausanne
Vladimir Parpura
Vladimir Parpura University of Alabama at Birmingham

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying neuroscience opens doors to a range of exciting graduate paths and professional careers. Many students interested in the brain, behavior, and health choose to complement their studies through online social work programs, which are a great choice for those committed to mental health and community support.

For those seeking to quickly enter the field, consider an accelerated psychology bachelor's degree. These programs offer the flexibility to finish sooner and begin working or pursuing advanced degrees more rapidly.

Counseling is another popular path for neuroscience graduates. If affordability is a concern, explore the cheapest cacrep-accredited programs online for high-quality, cost-effective counseling education. Additionally, prospective counselors can find budget-friendly options through the cheapest master's in counseling online.

Whether you pursue clinical, research, or community-focused roles, integrating neuroscience with related online programs can strengthen your skills and expand your career opportunities in mental health, education, or social care.

Best Scientists Citing Michael V. Sofroniew

Trending Scientists

Recently Published Articles