World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
76
Citations
27369
World Ranking
1807
National Ranking
61

Research.com Recognitions

  • 2015 - Member of Academia Europaea

Overview

Maarten van Lohuizen is affiliated with the Antoni van Leeuwenhoek Hospital in the Netherlands, focusing primarily on research in biochemistry, genetics, molecular biology, and medicine.

Their research contributions span several subfields including molecular biology, pulmonary and respiratory medicine, genetics, surgery, and hematology. The main topics addressed in their work include epigenetics and DNA methylation, occupational and environmental lung diseases, ubiquitin and proteasome pathways, medical imaging and pathology studies, interstitial lung diseases and idiopathic pulmonary fibrosis, histone deacetylase inhibitors research, and DNA repair mechanisms.

Van Lohuizen has published extensively in venues such as bioRxiv (Cold Spring Harbor Laboratory), SSRN Electronic Journal, Geburtshilfe und Frauenheilkunde, The Journal of Experimental Medicine, and Cell Reports.

Frequent co-authors in van Lohuizen's research network include Gaurav Kumar Pandey, Danielle Hulsman, Nick Landman, Jitendra Badhai, and Ji-Ying Song.

Recent notable publications include:

  • Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice, 2020, The Journal of Experimental Medicine
  • USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells, 2020, Cell Reports
  • Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma, 2023, Cell Reports Medicine
  • Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer, 2022, Breast Cancer Research
  • Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy, 2021, International Journal of Molecular Sciences

Van Lohuizen has been recognized as a Member of Academia Europaea since 2015, reflecting a role in the broader scientific community.

Best Publications

  • The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

    Jacqueline J. L. Jacobs;Karin Kieboom;Silvia Marino;Ronald A DePinho

  • Polycomb silencers control cell fate, development and cancer

    Anke Sparmann;Maarten van Lohuizen

  • Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

    Daan Peric-Hupkes;Wouter Meuleman;Wouter Meuleman;Ludo Pagie;Sophia W.M. Bruggeman

  • Identification of cooperating oncogenes in Eμ-myc transgenic mice by provirus tagging

    Maarten van Lohuizen;Sjef Verbeek;Blanca Scheljen;Ellen Wientjens

  • Stem Cells and Cancer: The Polycomb Connection

    Merel E. Valk-Lingbeek;Sophia W.M. Bruggeman;Maarten van Lohuizen

  • Predisposition to lymphomagenesis in pim-1 transgenic mice: Cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

    Maarten van Lohuizen;Sjef Verbeek;Paul Krimpenfort;Jos Domen

  • Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas

    Carly Leung;Merel Lingbeek;Olga Shakhova;James Liu

  • BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas.

    Sílvia Beà;Frederic Tort;Magda Pinyol;Xavier Puig

  • Epigenetics and cancer.

    Anders H. Lund;Maarten van Lohuizen

  • Enhanced self-renewal of hematopoietic stem cells mediated by the Polycomb gene product Bmi-1

    Atsushi Iwama;Hideyuki Oguro;Masamitsu Negishi;Yuko Kato

  • Control of the Replicative Life Span of Human Fibroblasts by p16 and the Polycomb Protein Bmi-1

    Koji Itahana;Koji Itahana;Ying Zou;Yoko Itahana;Jose Luis Martinez

  • The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells

    Goberdhan P. Dimri;Jose Luis Martinez;Jacqueline J L Jacobs;Petra Keblusek

  • Bmi1 regulates mitochondrial function and the DNA damage response pathway

    Jie Liu;Liu Cao;Jichun Chen;Shiwei Song

  • Structure and E3-ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b

    Gretel Buchwald;Petra van der Stoop;Oliver Weichenrieder;Anastassis Perrakis

  • Genome-wide profiling of PRC1 and PRC2 Polycomb chromatin binding in Drosophila melanogaster.

    Bas Tolhuis;Inhua Muijrers;Elzo de Wit;Hans Teunissen

  • Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation

    Petra E.M.H. Habets;Antoon F.M. Moorman;Danielle E.W. Clout;Marian A. van Roon

  • Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition

    Jan Willem Voncken;Bernard A. J. Roelen;Mieke Roefs;Stijn de Vries

  • Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice

    Sophia W.M. Bruggeman;Merel E. Valk-Lingbeek;Petra P.M. van der Stoop;Jacqueline J.L. Jacobs

  • Polycomb complexes and silencing mechanisms.

    Anders H Lund;Maarten van Lohuizen

  • Stem cell regulation by polycomb repressors: postponing commitment.

    Alexandra M Pietersen;Maarten van Lohuizen

Frequent Co-Authors

Lodewyk F. A. Wessels
Lodewyk F. A. Wessels Antoni van Leeuwenhoek Hospital
Anton Berns
Anton Berns Antoni van Leeuwenhoek Hospital
Jos Jonkers
Jos Jonkers Antoni van Leeuwenhoek Hospital
Anders H. Lund
Anders H. Lund University of Copenhagen
David J. Adams
David J. Adams Wellcome Sanger Institute
Bas van Steensel
Bas van Steensel Antoni van Leeuwenhoek Hospital
Arie P. Otte
Arie P. Otte University of Amsterdam
Antoine H.F.M. Peters
Antoine H.F.M. Peters Friedrich Miescher Institute
Silvia Marino
Silvia Marino Queen Mary University of London
Atsushi Iwama
Atsushi Iwama University of Tokyo

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring a career in Genetics opens doors to various interdisciplinary fields, including healthcare, research, and clinical practice. Many professionals in genetics-related roles choose to expand their qualifications with flexible online degrees, particularly in nursing and medical sciences.

Those interested in advanced patient care may consider enrolling in an online nurse practitioner program. Such programs can complement genetics expertise by equipping graduates to interpret genetic data for personalized care.

For a more generalist path, affordable online nursing programs offer flexible options for beginners or those transitioning from other fields. These programs often provide foundational medical knowledge valuable for genetics counselors or research coordinators.

Experienced nurses can further specialize with the most affordable bsn to dnp programs online, preparing for leadership roles that bridge clinical practice, genetics, and advanced patient care.

If you’re already a registered nurse, consider the career boost from rn to bsn programs. Such degrees enhance knowledge in genomics, ethics, and evidence-based care, directly impacting career prospects in genetics-driven healthcare.

Best Scientists Citing Maarten van Lohuizen

Trending Scientists