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Biology and Biochemistry

D-Index
87
Citations
88374
World Ranking
2763
National Ranking
1426

Medicine

D-Index
85
Citations
87814
World Ranking
14327
National Ranking
7243

Overview

Michael F. Clarke is affiliated with Stanford University in the United States. Their research focuses primarily on the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine.

Their work spans several subfields, including Molecular Biology, Cancer Research, Oncology, Biophysics, and Physiology. The main research topics covered by Clarke include Epigenetics and DNA Methylation, Cancer Genomics and Diagnostics, Single-cell and spatial transcriptomics, Cancer Cells and Metastasis, Cell Image Analysis Techniques, Cancer-related gene regulation, and Cancer-related molecular mechanisms research.

Frequent publication venues for Clarke include:

  • Nature
  • Journal of Clinical Oncology
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Among Clarke's recent papers are:

  • Single-cell transcriptional diversity is a hallmark of developmental potential, 2020, Science
  • A single-cell transcriptomic atlas characterizes ageing tissues in the mouse, 2020, Nature
  • Ageing hallmarks exhibit organ-specific temporal signatures, 2020, Nature
  • Molecular hallmarks of heterochronic parabiosis at single-cell resolution, 2022, Nature
  • Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets, 2022, Nature Computational Science

Frequent co-authors collaborating with Clarke include:

  • Stephen R. Quake
  • Jane Antony
  • Dalong Qian
  • Robert C. Jones
  • Gunsagar S. Gulati

Best Publications

  • Prospective identification of tumorigenic breast cancer cells

    Muhammad Al-Hajj;Max S. Wicha;Adalberto Benito-Hernandez;Sean J. Morrison;Sean J. Morrison

  • Stem cells, cancer, and cancer stem cells

    Tannishtha Reya;Tannishtha Reya;Sean J. Morrison;Michael F. Clarke;Irving L. Weissman

  • Identification of Pancreatic Cancer Stem Cells

    Chenwei Li;David G. Heidt;Piero Dalerba;Charles F. Burant

  • Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells.

    Michael F. Clarke;John E. Dick;Peter B. Dirks;Connie J. Eaves

  • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

    Gabriela Dontu;Wissam M. Abdallah;Jessica M. Foley;Kyle W. Jackson

  • Association of reactive oxygen species levels and radioresistance in cancer stem cells

    Maximilian Diehn;Robert W. Cho;Neethan A. Lobo;Tomer Kalisky

  • Phenotypic characterization of human colorectal cancer stem cells

    Piero Dalerba;Scott J. Dylla;In Kyung Park;Rui Liu

  • Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

    M. E. Prince;R. Sivanandan;A. Kaczorowski;G. T. Wolf

  • Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.

    In Kyung Park;Dalong Qian;Mark Kiel;Michael W. Becker

  • Applying the principles of stem-cell biology to cancer

    Ricardo Pardal;Michael F. Clarke;Sean J. Morrison

  • Cancer Stem Cells: Models and Concepts

    Piero Dalerba;Robert W. Cho;Michael F. Clarke

  • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

    Anna V. Molofsky;Ricardo Pardal;Toshihide Iwashita;In Kyung Park

  • The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors

    Stephen B. Willingham;Jens Peter Volkmer;Andrew J. Gentles;Debashis Sahoo

  • Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

    Yohei Shimono;Maider Zabala;Robert W. Cho;Neethan Lobo

  • The Biology of Cancer Stem Cells

    Neethan A. Lobo;Yohei Shimono;Dalong Qian;Michael F. Clarke

  • Self-renewal and solid tumor stem cells

    Muhammad Al-Hajj;Michael F Clarke

  • Stem Cells and Cancer: Two Faces of Eve

    Michael F. Clarke;Margaret Fuller

  • A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

    Nicole Almanzar;Jane Antony;Ankit S. Baghel

  • The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells

    Rui Liu;Xinhao Wang;Grace Y. Chen;Piero Dalerba;Piero Dalerba

  • Single-cell transcriptional diversity is a hallmark of developmental potential.

    Gunsagar S. Gulati;Shaheen S. Sikandar;Daniel J. Wesche;Anoop Manjunath

Frequent Co-Authors

Max S. Wicha
Max S. Wicha University of Michigan–Ann Arbor
Stephen G. Emerson
Stephen G. Emerson Columbia University
Stephen R. Quake
Stephen R. Quake Stanford University
Irving L. Weissman
Irving L. Weissman Stanford University
Bernhard O. Palsson
Bernhard O. Palsson University of California, San Diego
Sean J. Morrison
Sean J. Morrison The University of Texas Southwestern Medical Center
Gabriel Núñez
Gabriel Núñez University of Michigan–Ann Arbor
Maximilian Diehn
Maximilian Diehn Stanford University
George Somlo
George Somlo City Of Hope National Medical Center
Marvin S. Reitz
Marvin S. Reitz University of Maryland, Baltimore

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