World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
50
Citations
17743
World Ranking
2529
National Ranking
62

Overview

Diego Pasini is affiliated with the European Institute of Oncology in Italy. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with 67 publications in these areas. The main subfields of their work include molecular biology, cancer research, genetics, radiology, nuclear medicine and imaging, and neurology.

The scientist's research covers several key topics, such as epigenetics and DNA methylation, cancer-related gene regulation, RNA modifications and cancer, genomics and chromatin dynamics, genetics and neurodevelopmental disorders, ubiquitin and proteasome pathways, and retinal imaging and analysis.

Recent notable papers authored or co-authored by Diego Pasini include the following:

  • Identification of a choroid plexus vascular barrier closing during intestinal inflammation, 2021, Science
  • BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation, 2021, Molecular Cell
  • Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype, 2020, Science Translational Medicine
  • Cooperation Between MYC and β-Catenin in Liver Tumorigenesis Requires Yap/Taz, 2020, Hepatology
  • Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair, 2021, Science Advances

Diego Pasini frequently publishes in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Science Advances
  • Cell Reports
  • Nucleic Acids Research

The scientist has collaborated regularly with multiple co-authors, often working with:

  • Daria Manganaro
  • Simone Tamburri
  • Daniel Fernández-Pérez
  • Eric Conway
  • Simona Rodighiero

Best Publications

  • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

    Adrian P. Bracken;Nikolaj Dietrich;Diego Pasini;Klaus H. Hansen

  • UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

    Karl Agger;Paul A. C. Cloos;Jesper Christensen;Diego Pasini

  • EZH2 is downstream of the pRB‐E2F pathway, essential for proliferation and amplified in cancer

    Adrian P. Bracken;Diego Pasini;Maria Capra;Elena Prosperini

  • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

    Diego Pasini;Adrian P Bracken;Michael R Jensen;Eros Lazzerini Denchi

  • The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

    Adrian P. Bracken;Daniela Kleine-Kohlbrecher;Nikolaj Dietrich;Diego Pasini

  • A model for transmission of the H3K27me3 epigenetic mark

    Klaus H. Hansen;Adrian P. Bracken;Adrian P. Bracken;Diego Pasini;Nikolaj Dietrich

  • The Polycomb Group Protein Suz12 Is Required for Embryonic Stem Cell Differentiation

    Diego Pasini;Adrian P. Bracken;Jacob B. Hansen;Manuela Capillo

  • RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3

    Jesper Christensen;Karl Agger;Paul A.C. Cloos;Diego Pasini

  • JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

    Diego Pasini;Paul A C Cloos;Julian Walfridsson;Linda Olsson

  • Polycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity.

    Karin J. Ferrari;Andrea Scelfo;SriGanesh Jammula;Alessandro Cuomo

  • Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor

    Nicolás Herranz;Diego Pasini;Víctor M Díaz;Clara Francí

  • Amplification of Mdmx (or Mdm4) directly contributes to tumor formation by inhibiting p53 tumor suppressor activity

    Davide Danovi;Erik Meulmeester;Diego Pasini;Domenico Migliorini

  • Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

    Diego Pasini;Martina Malatesta;Hye Ryung Jung;Julian Walfridsson

  • Polycomb complexes act redundantly to repress genomic repeats and genes

    Martin Leeb;Diego Pasini;Maria Novatchkova;Markus Jaritz

  • Tet Proteins Connect the O-Linked N-acetylglucosamine Transferase Ogt to Chromatin in Embryonic Stem Cells

    Pietro Vella;Andrea Scelfo;SriGanesh Jammula;Fulvio Chiacchiera

  • Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2

    Diego Pasini;Klaus H. Hansen;Jesper Christensen;Karl Agger

  • Role of the Polycomb Repressive Complex 2 in Acute Promyelocytic Leukemia

    Raffaella Villa;Diego Pasini;Arantxa Gutierrez;Lluis Morey

  • Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression.

    Simone Tamburri;Elisa Lavarone;Daniel Fernández-Pérez;Daniel Fernández-Pérez;Eric Conway

  • Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies.

    Maria Apicella;Elisa Giannoni;Stephany Fiore;Karin Johanna Ferrari

  • 15 Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and the Polycomb Repressive Complex 2

    Diego Pasini;Klaus H. Hansen;Jesper Christensen;Karl Agger

Frequent Co-Authors

Kristian Helin
Kristian Helin Institute of Cancer Research
Tiziana Bonaldi
Tiziana Bonaldi European Institute of Oncology
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Pier Giuseppe Pelicci
Pier Giuseppe Pelicci European Institute of Oncology
Ole Nørregaard Jensen
Ole Nørregaard Jensen University of Southern Denmark
Bruno Amati
Bruno Amati European Institute of Oncology
Luciano Di Croce
Luciano Di Croce Centre for Genomic Regulation
Enzo Medico
Enzo Medico University of Turin
Wolfgang Fischle
Wolfgang Fischle King Abdullah University of Science and Technology

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