Victor E. Marquez

Overview

Best Publications

• DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

  Tina Branscombe Miranda;Connie C. Cortez;Christine B. Yoo;Gangning Liang

  688
  Citations

• Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.

  Damian B. Yap;Damian B. Yap;Justin Chu;Tobias Berg;Matthieu Schapira

  682
  Citations

• Inhibition of DNA Methylation and Reactivation of Silenced Genes by Zebularine

  Jonathan C. Cheng;Cindy B. Matsen;Felicidad A. Gonzales;Wei Ye

  662
  Citations

• EZH2 Is Essential for Glioblastoma Cancer Stem Cell Maintenance

  Mario-Luca Suvà;Nicolò Riggi;Michalina Janiszewska;Ivan Radovanovic

  528
  Citations

• Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.

  Warren Fiskus;Yongchao Wang;Arun Sreekumar;Kathleen M. Buckley

  422
  Citations

• TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

  Daniela Palacios;Chiara Mozzetta;Silvia Consalvi;Giuseppina Caretti;Giuseppina Caretti

  414
  Citations

• Preferential response of cancer cells to zebularine

  Jonathan C. Cheng;Christine B. Yoo;Daniel J. Weisenberger;Jody Chuang

  384
  Citations

• Nucleosides with a twist. Can fixed forms of sugar ring pucker influence biological activity in nucleosides and oligonucleotides

  Victor E. Marquez;Maqbool A. Siddiqui;Abdallah Ezzitouni;Pamela Russ

  370
  Citations

• Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction

  Ende Zhao;Ende Zhao;Tomasz Maj;Ilona Kryczek;Wei Li;Wei Li

  369
  Citations

• Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets

  Ionel Sandovici;Noel H Smith;Marloes Dekker Nitert;Matthew Ackers-Johnson

  364
  Citations

• Acid-stable 2'-fluoro purine dideoxynucleosides as active agents against HIV.

  Victor E. Marquez;Christopher K. H. Tseng;Hiroaki Mitsuya;Shizuko Aoki

  322
  Citations

• Coordinated Silencing of MYC-Mediated miR-29 by HDAC3 and EZH2 as a Therapeutic Target of Histone Modification in Aggressive B-Cell Lymphomas

  Xinwei Zhang;Xinwei Zhang;Xiaohong Zhao;Warren C Fiskus;Jianhong Lin

  313
  Citations

• Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.

  Jonathan C. Cheng;Daniel J. Weisenberger;Felicidad A. Gonzales;Gangning Liang

  302
  Citations

• Integrative Genomics Analysis Reveals Silencing of β-Adrenergic Signaling by Polycomb in Prostate Cancer

  Jindan Yu;Qi Cao;Rohit Mehra;Bharathi Laxman

  275
  Citations

• Epigenetic analysis of KSHV latent and lytic genomes.

  Zsolt Toth;Dennis T. Maglinte;Sun Hwa Lee;Hye-Ra Lee

  260
  Citations

• EZH2 inhibition sensitizes BRG1 and EGFR mutant lung tumours to TopoII inhibitors.

  Christine M. Fillmore;Christine M. Fillmore;Chunxiao Xu;Pooja T. Desai;Joanne M. Berry

  260
  Citations

• Differential Localization of Protein Kinase C δ by Phorbol Esters and Related Compounds Using a Fusion Protein with Green Fluorescent Protein

  Qiming J. Wang;Dipak Bhattacharyya;Susan Garfield;Kassoum Nacro

  259
  Citations

• PRC2 epigenetically silences Th1-type chemokines to suppress effector T cell trafficking in colon cancer

  Nisha Nagarsheth;Dongjun Peng;Ilona Kryczek;Ke Wu

  255
  Citations

• 3-Deazaneplanocin: a new and potent inhibitor of S-adenosylhomocysteine hydrolase and its effects on human promyelocytic leukemia cell line HL-60.

  Robert I. Glazer;Kathleen D. Hartman;Marion C. Knode;Michelle M. Richard

  212
  Citations

• Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents.

  Jiuxiang Zhu;Xueqin Song;Ho-Pi Lin;Donn C. Young

  210
  Citations