World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
16172
World Ranking
11216
National Ranking
317

Overview

Enzo Medico is affiliated with the University of Turin in Italy. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, they have contributed notably to subfields such as Molecular Biology, Oncology, Cancer Research, Immunology, and Pathology and Forensic Medicine.

The scientist's work covers several main topics that include:

  • Cancer Genomics and Diagnostics
  • CAR-T cell therapy research
  • Immune Cell Function and Interaction
  • Ubiquitin and proteasome pathways
  • Colorectal Cancer Treatments and Studies
  • Cancer-related gene regulation
  • Cancer Cells and Metastasis

Medico has published extensively, with recurrent contributions in publication venues such as:

  • Cancer Research (13 publications)
  • Clinical Cancer Research (3 publications)
  • Journal of Translational Medicine (3 publications)
  • Cancers (3 publications)
  • Nature Genetics (2 publications)

Noteworthy recent papers by Medico include:

  • Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts, 2021, Nature Genetics
  • Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype, 2020, Science Translational Medicine
  • Associations between hypovitaminosis D and COVID-19: a narrative review, 2020, Aging Clinical and Experimental Research
  • Patient-derived xenografts (PDXs) as model systems for human cancer, 2020, Current Opinion in Biotechnology
  • Machine learning for RNA sequencing-based intrinsic subtyping of breast cancer, 2020, Scientific Reports

Throughout their career, Medico has frequently collaborated with several researchers, including:

  • Claudio Isella (27 coauthored works)
  • Livio Trusolino (17 coauthored works)
  • Andrea Bertotti (14 coauthored works)
  • Consalvo Petti (14 coauthored works)
  • Federica Invrea (11 coauthored works)

Best Publications

  • Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

    Sandra Misale;Rona Yaeger;Sebastijan Hobor;Elisa Scala

  • Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

    Giulia Siravegna;Benedetta Mussolin;Michela Buscarino;Giorgio Corti

  • A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.

    Andrea Bertotti;Giorgia Migliardi;Francesco Galimi;Francesco Sassi

  • Expression of the Met/HGF receptor in normal and neoplastic human tissues.

    M. F. Di Renzo;R. P. Narsimhan;M. Olivero;S. Bretti

  • Stromal contribution to the colorectal cancer transcriptome

    Claudio Isella;Andrea Terrasi;Sara Erika Bellomo;Consalvo Petti

  • FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data

    Limin Fu;Enzo Medico

  • Interrogating open issues in cancer precision medicine with patient-derived xenografts

    Annette T. Byrne;Denis G. Alférez;Frédéric Amant;Daniela Annibali

  • Induction of MET by Ionizing Radiation and Its Role in Radioresistance and Invasive Growth of Cancer

    Francesca De Bacco;Paolo Luraghi;Enzo Medico;Gigliola Reato

  • The MET oncogene drives a genetic programme linking cancer to haemostasis.

    Carla Boccaccio;Gabriella Sabatino;Enzo Medico;Flavia Girolami

  • The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

    Enzo Medico;Mariangela Russo;Gabriele Picco;Carlotta Cancelliere

  • Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer

    Claudio Isella;Francesco Brundu;Sara Erika Bellomo;Francesco Galimi

  • Neural differentiation of human mesenchymal stem cells: evidence for expression of neural markers and eag K+ channel types

    Katia Mareschi;Monica Novara;Deborah Rustichelli;Ivana Ferrero

  • Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies.

    Maria Apicella;Elisa Giannoni;Stephany Fiore;Karin Johanna Ferrari

  • Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells.

    Michele De Palma;Eugenio Montini;Francesca R Santoni de Sio;Fabrizio Benedicenti

  • Phosphorylation of serine 985 negatively regulates the hepatocyte growth factor receptor kinase.

    Lucia Gandino;Paola Longati;Enzo Medico;Maria Prat

  • Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.

    S Giordano;Z Zhen;E Medico;G Gaudino

  • The tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro.

    E Medico;A M Mongiovi;J Huff;M A Jelinek

  • The MET oncogene is a functional marker of a glioblastoma stem cell subtype

    Francesca De Bacco;Elena Casanova;Enzo Medico;Serena Pellegatta

  • Gene Expression Profiling Uncovers Molecular Classifiers for the Recognition of Anaplastic Large-Cell Lymphoma Within Peripheral T-Cell Neoplasms

    Roberto Piva;Luca Agnelli;Elisa Pellegrino;Katia Todoerti

  • Increased lactate secretion by cancer cells sustains non-cell-autonomous adaptive resistance to MET and EGFR targeted therapies. Apicella et al.

    Maria Apicella;Elisa Giannoni;Stephany Fiore;Karin Ferrari

Frequent Co-Authors

Paolo M. Comoglio
Paolo M. Comoglio FIRC Institute of Molecular Oncology
Alberto Bardelli
Alberto Bardelli University of Turin
Giorgio Inghirami
Giorgio Inghirami Cornell University
Anna Sapino
Anna Sapino University of Turin
Silvia Giordano
Silvia Giordano University of Turin
Paolo Provero
Paolo Provero University of Turin
Salvatore Siena
Salvatore Siena University of Milan
Jos Jonkers
Jos Jonkers Antoni van Leeuwenhoek Hospital
Antonino Neri
Antonino Neri University of Milan
Carol J. Bult
Carol J. Bult European Bioinformatics Institute

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