2023 - Research.com Molecular Biology in Italy Leader Award
2022 - Research.com Genetics and Molecular Biology in Italy Leader Award
Member of the European Molecular Biology Organization (EMBO)
Paolo M. Comoglio mostly deals with Hepatocyte growth factor, Receptor tyrosine kinase, Tyrosine kinase, Cancer research and Cell biology. To a larger extent, Paolo M. Comoglio studies Receptor with the aim of understanding Hepatocyte growth factor. His Receptor tyrosine kinase research is multidisciplinary, incorporating elements of Hepatocyte Growth Factor Receptor, Proto-oncogene tyrosine-protein kinase Src, ROR1, Platelet-derived growth factor receptor and Growth factor receptor.
His research integrates issues of Molecular biology, Oncogene, C-Met and Myogenesis in his study of Tyrosine kinase. His study explores the link between Cancer research and topics such as Cell surface receptor that cross with problems in Receptor Protein-Tyrosine Kinases. His study in Cell biology is interdisciplinary in nature, drawing from both Semaphorin, Plexin and Cell adhesion.
Paolo M. Comoglio mainly focuses on Cancer research, Cell biology, Molecular biology, Hepatocyte growth factor and Receptor tyrosine kinase. His research on Cancer research also deals with topics like
His studies deal with areas such as Cell culture, Biochemistry, Antigen, Rous sarcoma virus and Antibody as well as Molecular biology. His Hepatocyte growth factor research includes elements of Growth factor, Paracrine signalling, Autocrine signalling and Cell growth. The various areas that Paolo M. Comoglio examines in his Receptor tyrosine kinase study include Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src, ROR1, Platelet-derived growth factor receptor and Tyrosine phosphorylation.
The scientist’s investigation covers issues in Cancer research, Cancer, Cell biology, Lung cancer and Microtubule dynamics. His Cancer research research is multidisciplinary, relying on both Receptor, Hepatocyte growth factor, Cancer cell, Targeted therapy and Kinase. His Receptor study combines topics from a wide range of disciplines, such as Apoptosis and Programmed cell death.
His studies in Hepatocyte growth factor integrate themes in fields like Tumor microenvironment, Receptor tyrosine kinase and Paracrine signalling. His Receptor tyrosine kinase research is included under the broader classification of Signal transduction. He has researched Cancer in several fields, including Tyrosine kinase and Antibody, Immunology.
His primary areas of study are Cancer research, Cancer, Hepatocyte growth factor, Receptor tyrosine kinase and Internal medicine. Paolo M. Comoglio combines subjects such as Cetuximab, Tyrosine kinase, Phosphorylation, PI3K/AKT/mTOR pathway and Kinase with his study of Cancer research. The study incorporates disciplines such as Lung cancer and Drug resistance in addition to Tyrosine kinase.
Paolo M. Comoglio interconnects Pharmacology and Cell fate determination in the investigation of issues within Hepatocyte growth factor. His Receptor tyrosine kinase study focuses on Signal transduction and Receptor. His research in Internal medicine intersects with topics in Endocrinology, Epigenetics, Oncology and Pathology.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth
F Bussolino;M F Di Renzo;M Ziche;E Bocchietto.
Journal of Cell Biology (1992)
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene.
Selma Pennacchietti;Paolo Michieli;Maria Galluzzo;Massimiliano Mazzone.
Cancer Cell (2003)
Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.
Luca Tamagnone;Stefania Artigiani;Hang Chen;Zhigang He.
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family
Carola Ponzetto;Alberto Bardelli;Alberto Bardelli;Zhu Zhen;Flavio Maina.
MET signalling: principles and functions in development, organ regeneration and cancer.
Livio Trusolino;Andrea Bertotti;Paolo M. Comoglio.
Nature Reviews Molecular Cell Biology (2010)
Drug development of MET inhibitors : targeting oncogene addiction and expedience
Paolo M. Comoglio;Silvia Giordano;Livio Trusolino.
Nature Reviews Drug Discovery (2008)
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.
L Naldini;E Vigna;R P Narsimhan;G Gaudino.
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Andrea Bertotti;Giorgia Migliardi;Francesco Galimi;Francesco Sassi.
Cancer Discovery (2011)
Scatter-factor and semaphorin receptors: cell signalling for invasive growth
Livio Trusolino;Paolo M. Comoglio.
Nature Reviews Cancer (2002)
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial
Andrea Sartore-Bianchi;Livio Trusolino;Cosimo Martino;Katia Bencardino.
Lancet Oncology (2016)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: