D-Index & Metrics Best Publications
Molecular Biology
Italy
2023
Genetics and Molecular Biology
Italy
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 129 Citations 54,100 504 World Ranking 112 National Ranking 2

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in Italy Leader Award

2022 - Research.com Genetics and Molecular Biology in Italy Leader Award

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

Paolo M. Comoglio mostly deals with Hepatocyte growth factor, Receptor tyrosine kinase, Tyrosine kinase, Cancer research and Cell biology. To a larger extent, Paolo M. Comoglio studies Receptor with the aim of understanding Hepatocyte growth factor. His Receptor tyrosine kinase research is multidisciplinary, incorporating elements of Hepatocyte Growth Factor Receptor, Proto-oncogene tyrosine-protein kinase Src, ROR1, Platelet-derived growth factor receptor and Growth factor receptor.

His research integrates issues of Molecular biology, Oncogene, C-Met and Myogenesis in his study of Tyrosine kinase. His study explores the link between Cancer research and topics such as Cell surface receptor that cross with problems in Receptor Protein-Tyrosine Kinases. His study in Cell biology is interdisciplinary in nature, drawing from both Semaphorin, Plexin and Cell adhesion.

His most cited work include:

  • Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth (1230 citations)
  • Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. (1064 citations)
  • Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates. (985 citations)

What are the main themes of his work throughout his whole career to date?

Paolo M. Comoglio mainly focuses on Cancer research, Cell biology, Molecular biology, Hepatocyte growth factor and Receptor tyrosine kinase. His research on Cancer research also deals with topics like

  • Receptor which intersects with area such as Cell,
  • Cancer together with Immunology. His biological study spans a wide range of topics, including Semaphorin and Lung cancer.

His studies deal with areas such as Cell culture, Biochemistry, Antigen, Rous sarcoma virus and Antibody as well as Molecular biology. His Hepatocyte growth factor research includes elements of Growth factor, Paracrine signalling, Autocrine signalling and Cell growth. The various areas that Paolo M. Comoglio examines in his Receptor tyrosine kinase study include Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src, ROR1, Platelet-derived growth factor receptor and Tyrosine phosphorylation.

He most often published in these fields:

  • Cancer research (35.77%)
  • Cell biology (27.34%)
  • Molecular biology (25.84%)

What were the highlights of his more recent work (between 2011-2021)?

  • Cancer research (35.77%)
  • Cancer (10.67%)
  • Cell biology (27.34%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cancer research, Cancer, Cell biology, Lung cancer and Microtubule dynamics. His Cancer research research is multidisciplinary, relying on both Receptor, Hepatocyte growth factor, Cancer cell, Targeted therapy and Kinase. His Receptor study combines topics from a wide range of disciplines, such as Apoptosis and Programmed cell death.

His studies in Hepatocyte growth factor integrate themes in fields like Tumor microenvironment, Receptor tyrosine kinase and Paracrine signalling. His Receptor tyrosine kinase research is included under the broader classification of Signal transduction. He has researched Cancer in several fields, including Tyrosine kinase and Antibody, Immunology.

Between 2011 and 2021, his most popular works were:

  • Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer (435 citations)
  • Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial (410 citations)
  • Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis (189 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

His primary areas of study are Cancer research, Cancer, Hepatocyte growth factor, Receptor tyrosine kinase and Internal medicine. Paolo M. Comoglio combines subjects such as Cetuximab, Tyrosine kinase, Phosphorylation, PI3K/AKT/mTOR pathway and Kinase with his study of Cancer research. The study incorporates disciplines such as Lung cancer and Drug resistance in addition to Tyrosine kinase.

Paolo M. Comoglio interconnects Pharmacology and Cell fate determination in the investigation of issues within Hepatocyte growth factor. His Receptor tyrosine kinase study focuses on Signal transduction and Receptor. His research in Internal medicine intersects with topics in Endocrinology, Epigenetics, Oncology and Pathology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

F Bussolino;M F Di Renzo;M Ziche;E Bocchietto.
Journal of Cell Biology (1992)

1611 Citations

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene.

Selma Pennacchietti;Paolo Michieli;Maria Galluzzo;Massimiliano Mazzone.
Cancer Cell (2003)

1487 Citations

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

Luca Tamagnone;Stefania Artigiani;Hang Chen;Zhigang He.
Cell (1999)

1315 Citations

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

Carola Ponzetto;Alberto Bardelli;Alberto Bardelli;Zhu Zhen;Flavio Maina.
Cell (1994)

1180 Citations

MET signalling: principles and functions in development, organ regeneration and cancer.

Livio Trusolino;Andrea Bertotti;Paolo M. Comoglio.
Nature Reviews Molecular Cell Biology (2010)

1176 Citations

Drug development of MET inhibitors : targeting oncogene addiction and expedience

Paolo M. Comoglio;Silvia Giordano;Livio Trusolino.
Nature Reviews Drug Discovery (2008)

917 Citations

Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET.

L Naldini;E Vigna;R P Narsimhan;G Gaudino.
Oncogene (1991)

911 Citations

A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.

Andrea Bertotti;Giorgia Migliardi;Francesco Galimi;Francesco Sassi.
Cancer Discovery (2011)

864 Citations

Scatter-factor and semaphorin receptors: cell signalling for invasive growth

Livio Trusolino;Paolo M. Comoglio.
Nature Reviews Cancer (2002)

861 Citations

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial

Andrea Sartore-Bianchi;Livio Trusolino;Cosimo Martino;Katia Bencardino.
Lancet Oncology (2016)

836 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Paolo M. Comoglio

Toshikazu Nakamura

Toshikazu Nakamura

Osaka University

Publications: 214

Kunio Matsumoto

Kunio Matsumoto

Kanazawa University

Publications: 164

Ravi Salgia

Ravi Salgia

City Of Hope National Medical Center

Publications: 78

Atsushi Kumanogoh

Atsushi Kumanogoh

Osaka University

Publications: 70

Alberto Bardelli

Alberto Bardelli

University of Turin

Publications: 64

Federico Bussolino

Federico Bussolino

University of Turin

Publications: 61

Donald P. Bottaro

Donald P. Bottaro

National Institutes of Health

Publications: 59

Morag Park

Morag Park

McGill University

Publications: 57

Luca Tamagnone

Luca Tamagnone

Catholic University of the Sacred Heart

Publications: 56

George F. Vande Woude

George F. Vande Woude

Van Andel Institute

Publications: 52

George K. Michalopoulos

George K. Michalopoulos

University of Pittsburgh

Publications: 50

Salvatore Siena

Salvatore Siena

University of Milan

Publications: 50

James Christensen

James Christensen

Pfizer (United States)

Publications: 48

Ermanno Gherardi

Ermanno Gherardi

University of Pavia

Publications: 44

Naomi Kitamura

Naomi Kitamura

Tokyo Institute of Technology

Publications: 43

Pascale Cossart

Pascale Cossart

Institut Pasteur

Publications: 43

Trending Scientists

Dietrich A. Volmer

Dietrich A. Volmer

Humboldt-Universität zu Berlin

Taka-aki Okamura

Taka-aki Okamura

Osaka University

Angelo Albini

Angelo Albini

University of Pavia

Gary L. Bowlin

Gary L. Bowlin

University of Memphis

Michael J. Goss

Michael J. Goss

University of Guelph

Edwin S. Levitan

Edwin S. Levitan

University of Pittsburgh

Carol Soderlund

Carol Soderlund

University of Arizona

Thomas C. Friedrich

Thomas C. Friedrich

University of Wisconsin–Madison

Marianne Baas

Marianne Baas

Delft University of Technology

Andrés Mora

Andrés Mora

Ecopetrol (Colombia)

Andrea A. Kühn

Andrea A. Kühn

Charité - University Medicine Berlin

Jennifer L. Skeem

Jennifer L. Skeem

University of California, Berkeley

Susan R. Leekam

Susan R. Leekam

Cardiff University

Bruce Neal

Bruce Neal

George Institute for Global Health

Donald J. Tindall

Donald J. Tindall

Mayo Clinic

Hilary Charlesworth

Hilary Charlesworth

University of Melbourne

Something went wrong. Please try again later.