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Hans F. A. Vasen

Hans F. A. Vasen

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Medicine
Netherlands
2023

D-Index & Metrics

Medicine

D-Index
128
Citations
61602
World Ranking
2709
National Ranking
103

Research.com Recognitions

  • 2023 - Research.com Medicine in Netherlands Leader Award

Overview

Hans F. A. Vasen is a researcher affiliated with Leiden University in the Netherlands. Their work primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, focusing on oncology and related biomedical disciplines.

The main fields of study explored by Vasen include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broad categories, their research subfields are concentrated in:

  • Oncology
  • Pathology and Forensic Medicine
  • Cancer Research
  • Surgery
  • Molecular Biology

Vasen's research covers several topics, especially in relation to genetic and diagnostic aspects of cancer. The primary topics investigated include:

  • Genetic factors in colorectal cancer
  • Colorectal Cancer Screening and Detection
  • Pancreatic and Hepatic Oncology Research
  • Cancer Genomics and Diagnostics
  • Multiple and Secondary Primary Cancers
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Treatments and Studies

The researcher has contributed to numerous papers in reputable scientific venues. Frequent publication outlets include:

  • Familial Cancer (12 publications)
  • Gastroenterology (7 publications)
  • Genetics in Medicine (3 publications)
  • Pancreatology (3 publications)
  • Journal of Clinical Oncology (2 publications)

Among recent published works are:

  • Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome, 2020, Gastroenterology
  • The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance, 2020, International Journal of Cancer
  • Pancreatic Cancer Surveillance in Carriers of a Germline CDKN2A Pathogenic Variant: Yield and Outcomes of a 20-Year Prospective Follow-Up, 2022, Journal of Clinical Oncology
  • Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers, 2020, Genetics in Medicine
  • Surveillance for Pancreatic Cancer in High-Risk Individuals Leads to Improved Outcomes: A Propensity Score-Matched Analysis, 2023, Gastroenterology

Vasen often collaborates with a consistent group of co-authors, including:

  • Monique E. van Leerdam
  • Bert A. Bonsing
  • Derk C.F. Klatte
  • Jurjen J. Boonstra
  • Martin N.J.M. Wasser

Best Publications

  • Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

    D Ford;D F Easton;M Stratton;S Narod

  • Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite Instability

    Asad Umar;C. Richard Boland;Jonathan P. Terdiman;Sapna Syngal

  • New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.

    Hans F.A. Vasen;Patrice Watson;Jukka–Pekka Mecklin;Henry T. Lynch

  • The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC).

    H. F. A. Vasen;J. P. Mecklin;P. Meera Khan;H. T. Lynch

  • Mutations Predisposing to Hereditary Nonpolyposis Colorectal Cancer: Database and Results of a Collaborative Study

    Paivi Peltomaki;Hans F. A. Vasen

  • Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

    John Burn;Anne Marie Gerdes;Finlay MacRae;Jukka Pekka Mecklin

  • Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.

    HF Vasen;JT Wijnen;FH Menko;JH Kleibeuker

  • Peutz–Jeghers syndrome: a systematic review and recommendations for management

    A. D. Beggs;A. R. Latchford;H. F. A. Vasen;G. Moslein

  • Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

    Hans F A Vasen;Ignacio Blanco;Katja Aktan-Collan;Jessica P Gopie

  • Guidelines for the clinical management of familial adenomatous polyposis (FAP)

    H. F. A Vasen;G. Moslein;A. Alonso;S. Aretz

  • Guidelines for the clinical management of Lynch syndrome (hereditary non-polyposis cancer)

    Hans F.A. Vasen;Gabriele Möslein;Angel Alonso;Inge Bernstein

  • The risk of extra‐colonic, extra‐endometrial cancer in the Lynch syndrome

    Patrice Watson;Hans F.A. Vasen;Jukka Pekka Mecklin;Inge Bernstein

  • Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC/INSiGHT mutation database.

    Päivi Peltomäki;Hans Vasen

  • Duodenal adenomatosis in familial adenomatous polyposis

    S Bülow;J Björk;I J Christensen;O Fausa

  • Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database

    Pål Møller;Toni T Seppälä;Inge Bernstein;Inge Bernstein;Elke Holinski-Feder

  • Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database

    Pal Moller;Toni Seppala;Inge Bernstein;Inge Bernstein;Elke Holinski-Feder

  • Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden).

    H.F.A. Vasen;N.A. Gruis;R.R. Frants;P.A. van der Velden

  • Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.

    Yvonne M C Hendriks;Anja Wagner;Hans Morreau;Fred Menko

  • Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

    Mev Dominguez-Valentin;Julian R. Sampson;Toni T. Seppälä;Sanne W. ten Broeke

  • Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer

    John Burn;Anne-Marie Gerdes;Finlay Macrae;Jukka-Pekka Mecklin

Frequent Co-Authors

Juul T. Wijnen
Juul T. Wijnen Leiden University Medical Center
Frederik J. Hes
Frederik J. Hes Vrije Universiteit Brussel
Jan H. Kleibeuker
Jan H. Kleibeuker University Medical Center Groningen
Pål Møller
Pål Møller Oslo University Hospital
Fred H. Menko
Fred H. Menko Netherlands Cancer Institute
Riccardo Fodde
Riccardo Fodde Erasmus MC
Hans Morreau
Hans Morreau Leiden University Medical Center
John Burn
John Burn Newcastle University
Rolf H. Sijmons
Rolf H. Sijmons University of Groningen
D. Gareth Evans
D. Gareth Evans University of Manchester

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