2012 - Fellow of the American Association for the Advancement of Science (AAAS)
Part of his project on Catalysis includes research on Enantioselective synthesis and Transition state. Olaf Wiest integrates Enantioselective synthesis and Stereochemistry in his studies. While working in this field, Olaf Wiest studies both Stereochemistry and Enzyme. He brings together Enzyme and Biochemistry to produce work in his papers. His study on Biochemistry is mostly dedicated to connecting different topics, such as Gene isoform. His research ties Molecule and Organic chemistry together. While working in this field, Olaf Wiest studies both Gene and Cell biology. He combines Cell biology and Gene in his research. Olaf Wiest performs multidisciplinary study on Computational chemistry and Density functional theory in his works.
His Organic chemistry study frequently links to adjacent areas such as Ion. In his papers, he integrates diverse fields, such as Catalysis and Photochemistry. Olaf Wiest conducts interdisciplinary study in the fields of Photochemistry and Catalysis through his works. Olaf Wiest undertakes interdisciplinary study in the fields of Stereochemistry and Molecule through his works. Olaf Wiest integrates many fields, such as Molecule and Stereochemistry, in his works. In his work, he performs multidisciplinary research in Computational chemistry and Density functional theory. In his works, he conducts interdisciplinary research on Density functional theory and Computational chemistry. Olaf Wiest conducts interdisciplinary study in the fields of Biochemistry and DNA through his works. Olaf Wiest undertakes multidisciplinary studies into DNA and Biochemistry in his work.
His Organic chemistry study frequently links to other fields, such as Nickel. His studies link Organic chemistry with Nickel. Olaf Wiest incorporates Catalysis and Phosphine in his studies. In his works, he conducts interdisciplinary research on Phosphine and Catalysis. His study deals with a combination of Combinatorial chemistry and High-throughput screening. High-throughput screening and Virtual screening are two areas of study in which Olaf Wiest engages in interdisciplinary work. Borrowing concepts from Combinatorial chemistry, Olaf Wiest weaves in ideas under Virtual screening. Biochemistry is frequently linked to Dihydroxylation in his study. Many of his studies involve connections with topics such as Biochemistry and Dihydroxylation.
While working on this project, Olaf Wiest studies both Combinatorial chemistry and Virtual screening. He undertakes multidisciplinary investigations into Virtual screening and Ligand (biochemistry) in his work. He undertakes interdisciplinary study in the fields of Ligand (biochemistry) and Receptor through his research. In his works, Olaf Wiest undertakes multidisciplinary study on Receptor and Biochemistry. His Biochemistry study frequently involves adjacent topics like High-throughput screening. High-throughput screening and Combinatorial chemistry are two areas of study in which Olaf Wiest engages in interdisciplinary work. While working in this field, Olaf Wiest studies both Catalysis and Dihydroxylation. His Dihydroxylation study typically links adjacent topics like Enantioselective synthesis. Olaf Wiest connects Enantioselective synthesis with Catalysis in his research.
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Selective inhibition of BET bromodomains.
Panagis Filippakopoulos;Jun Qi;Sarah Picaud;Yao Shen.
A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria
Alassane Mbengue;Souvik Bhattacharjee;Trupti Pandharkar;Haining Liu.
Quantum Mechanical Methods and the Interpretation and Prediction of Pericyclic Reaction Mechanisms
Olaf Wiest;Daniel C. Montiel;K. N. Houk.
Journal of Physical Chemistry A (1997)
Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases.
Di-Fei Wang;Paul Helquist;Norbert L Wiech;Olaf Wiest.
Journal of Medicinal Chemistry (2005)
DENSITY FUNCTIONAL THEORY ISOTOPE EFFECTS AND ACTIVATION ENERGIES FOR THE COPE AND CLAISEN REARRANGEMENTS
Olaf Wiest;Kersey A. Black;K. N. Houk.
Journal of the American Chemical Society (1994)
Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts
Nina H. Pipalia;Casey C. Cosner;Amy Huang;Anamitra Chatterjee.
Proceedings of the National Academy of Sciences of the United States of America (2011)
On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors.
Di-Fei Wang;Olaf Wiest;Paul Helquist;Hsuan-Yin Lan-Hargest.
Journal of Medicinal Chemistry (2004)
Mechanism, Reactivity, and Selectivity in Palladium-Catalyzed Redox-Relay Heck Arylations of Alkenyl Alcohols
Liping Xu;Margaret J. Hilton;Xinhao Zhang;Per Ola Norrby;Per Ola Norrby.
Journal of the American Chemical Society (2014)
Comparative Genome-Scale Metabolic Reconstruction and Flux Balance Analysis of Multiple Staphylococcus aureus Genomes Identify Novel Antimicrobial Drug Targets
Deok-Sun Lee;Deok-Sun Lee;Deok-Sun Lee;Henry Burd;Jiangxia Liu;Eivind Almaas.
Journal of Bacteriology (2009)
Synergy of combining sonolysis and photocatalysis in the degradation and mineralization of chlorinated aromatic compounds.
Julie Peller;Olaf Wiest;Prashant V. Kamat.
Environmental Science & Technology (2003)
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