World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
49
Citations
7719
World Ranking
14931
National Ranking
3807

Paul Helquist publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Paul Helquist sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 251 publications — 50th percentile

50% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Paul Helquist D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Paul Helquist sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 49 D-Index — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Paul Helquist is affiliated with the University of Notre Dame in the United States. Their research spans various fields within biochemistry, genetics, and molecular biology, with a strong focus on molecular biology, materials chemistry, physiology, organic chemistry, and computational theory and mathematics.

Their scientific contributions include work on diverse topics, notably:

  • Plant biochemistry and biosynthesis
  • Computational drug discovery methods
  • Protein structure and dynamics
  • Machine learning in materials science
  • Lysosomal storage disorders research
  • Enzyme structure and function
  • Microbial metabolism and applications

Helquist has published extensively, with frequent appearances in several scientific journals. The main publication venues include:

  • Biophysical Journal
  • The Journal of Organic Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Cambridge Structural Database
  • Organic Letters

Among Helquist's recent papers are:

  • "Negative Data in Data Sets for Machine Learning Training," 2023, Organic Letters
  • "Negative Data in Data Sets for Machine Learning Training," 2023, The Journal of Organic Chemistry
  • "Transition State Force Field for the Asymmetric Redox-Relay Heck Reaction," 2020, Journal of the American Chemical Society
  • "Interplay of Computation and Experiment in Enantioselective Catalysis: Rationalization, Prediction, andCorrection?," 2023, ACS Catalysis
  • "HSP90 inhibitors reduce cholesterol storage in Niemann-Pick type C1 mutant fibroblasts," 2021, Journal of Lipid Research

Helquist has collaborated frequently with several researchers, including:

  • Olaf Wiest
  • Per-Ola Norrby
  • Cynthia V. Stauffacher
  • C.N. Steussy
  • Anthony R. Rosales

Best Publications

  • Reaction of aryl and vinyl halides with zerovalent nickel - preparative aspects and the synthesis of alnusone

    M. F. Semmelhack;Paul Helquist;L. D. Jones;Leonard Keller;Leonard Keller

  • Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition

    Yasuyuki Miyake;Jeremy J Keusch;Longlong Wang;Makoto Saito

  • Synthesis with Zerovalent Nickel. Coupling of Alkenyl Halides with Bis(1,5-cyclooctadiene)nickel(0)

    M. F. Semmelhack;P. M. Helquist;J. D. Gorzynski

  • Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases.

    Di-Fei Wang;Paul Helquist;Norbert L Wiech;Olaf Wiest

  • Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts

    Nina H. Pipalia;Casey C. Cosner;Amy Huang;Anamitra Chatterjee

  • On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors.

    Di-Fei Wang;Olaf Wiest;Paul Helquist;Hsuan-Yin Lan-Hargest

  • Synthesis of primary aryl amines through a copper-assisted aromatic substitution reaction with sodium azide.

    John T Markiewicz;Olaf Wiest;Paul Helquist

  • Rapid virtual screening of enantioselective catalysts using CatVS

    Anthony R. Rosales;Jessica Wahlers;Elaine Limé;Rebecca E. Meadows

  • An efficient, palladium-catalyzed route to protected allylic amines

    Richard D. Connell;Tobias Rein;Bjoern Aakermark;Paul Helquist

  • Selective oxidation of benzylic and allylic alcohols using Mn(OAc)3/catalytic 2,3-dichloro-5,6-dicyano-1,4-benzoquinone.

    Casey C. Cosner;Pablo J. Cabrera;Katherine M. Byrd;Asia M. Adams Thomas

  • Prediction of enantioselectivity in rhodium catalyzed hydrogenations.

    Patrick J. Donoghue;Paul Helquist;Per-Ola Norrby;Olaf Wiest

  • Highly stereoselective synthesis of trisubstituted olefins via addition of alkylcopper complexes to acetylenes

    Anthony Marfat;Paul R. McGuirk;Paul Helquist

  • Palladium‐ and Nickel‐Catalyzed Alkenylation of Enolates

    Tobias Ankner;Casey C. Cosner;Paul Helquist;Paul Helquist

  • Functionalized oxazoles from rhodiumi-catalyzed reaction of dimethyl diazomalonate with nitriles

    Richard Connell;Frank Scavo;Paul Helquist;Björn Åkermark

  • Thiadiazole Carbamates: Potent Inhibitors of Lysosomal Acid Lipase and Potential Niemann−Pick Type C Disease Therapeutics

    Anton I. Rosenbaum;Casey C. Cosner;Christopher J. Mariani;Frederick R. Maxfield

  • Inhibition of Histone Deacetylases: A Pharmacological Approach to the Treatment of Non-Cancer Disorders

    Norbert L. Wiech;Jed F. Fisher;Paul Helquist;Olaf Wiest

  • Intramolecular hydroamination of aminoalkynes with silver-phenanthroline catalysts.

    Jeffrey M. Carney;Patrick J. Donoghue;William M. Wuest;Olaf Wiest

  • Molecular Mechanics Predictions and Experimental Testing of Asymmetric Palladium-Catalyzed Allylation Reactions Using New Chiral Phenanthroline Ligands

    Unknown

  • Cyclopentene and cyclohexene annulation via copper-catalyzed conjugate addition of acetal-containing Grignard reagents

    Swati A. Bal;Anthony Marfat;Paul Helquist

  • Development of a Q2MM Force Field for the Asymmetric Rhodium Catalyzed Hydrogenation of Enamides.

    Patrick J. Donoghue;Paul Helquist;Per-Ola Norrby;Olaf Wiest

  • Enantioselective Synthesis of Salmeterol via Asymmetric Borane Reduction.

    Robert Hett;Ragnar Stare;Paul Helquist

Frequent Co-Authors

Olaf Wiest
Olaf Wiest University of Notre Dame
Per-Ola Norrby
Per-Ola Norrby AstraZeneca (Sweden)
Martin Tenniswood
Martin Tenniswood University at Albany, State University of New York
Björn Åkermark
Björn Åkermark Stockholm University
Frederick R. Maxfield
Frederick R. Maxfield Cornell University
Marvin J. Miller
Marvin J. Miller University of Notre Dame
Martin F. Semmelhack
Martin F. Semmelhack Princeton University
Qian Peng
Qian Peng Chinese Academy of Sciences
Patrick Matthias
Patrick Matthias Friedrich Miescher Institute
Daniel Hess
Daniel Hess Friedrich Miescher Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Chemistry in the USA opens the door to a variety of online degrees and career opportunities beyond traditional laboratory work. Many students explore specialized paths such as pharmaceutical sales, forensic science, or legal support roles related to chemical industries.

If you’re interested in legal aspects surrounding chemicals and patents, understanding the types of paralegals and salaries can help you decide whether to pursue a paralegal degree online.

For those inclined towards the pharmaceutical field, careers like becoming a drug rep offer dynamic roles that combine chemistry knowledge with client interaction. It’s important to research is it hard to become a pharmacist if you plan on deeper specialization with patient-focused responsibilities requiring advanced degrees.

Alternatively, chemistry graduates interested in forensic and medical sectors might consider roles such as an autopsy technician, where knowledge of chemical reactions and bodily processes is essential. Learn more about autopsy technician jobs to understand the educational requirements and job outlook in this field.

Best Scientists Citing Paul Helquist

Trending Scientists

Recently Published Articles