What is he best known for?
The fields of study he is best known for:
- Gene
- DNA
- Transcription factor
Patrick Matthias mostly deals with Molecular biology, Cell biology, HDAC6, Transcription factor and Microtubule.
His work carried out in the field of Molecular biology brings together such families of science as Histone octamer, Coactivator, Transcription, B cell and Promoter.
Patrick Matthias has researched Histone octamer in several fields, including Octamer transcription factor and DNA-binding protein.
His work deals with themes such as RNA, Cell nucleus, Gel electrophoresis and Molecular probe, which intersect with DNA-binding protein.
He works mostly in the field of Cell biology, limiting it down to concerns involving Aggresome and, occasionally, Dynactin, Viral replication, Ribonucleoprotein and Dynein.
His HDAC6 study improves the overall literature in Biochemistry.
His most cited work include:
- Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells (3875 citations)
- HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo (566 citations)
- Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally (398 citations)
What are the main themes of his work throughout his whole career to date?
Patrick Matthias spends much of his time researching Cell biology, Molecular biology, Transcription factor, HDAC6 and Acetylation.
His Cell biology research is multidisciplinary, relying on both Genetics, Aggresome, Cellular differentiation, T cell and Histone.
His Molecular biology study integrates concerns from other disciplines, such as Histone octamer, B cell, Enhancer, Transcription and Promoter.
The various areas that he examines in his Histone octamer study include Octamer transcription factor and DNA-binding protein.
His studies deal with areas such as Chromatin, Psychological repression and Activator as well as Transcription factor.
His research in HDAC6 intersects with topics in Hsp90, Microtubule and Ubiquitin.
He most often published in these fields:
- Cell biology (44.53%)
- Molecular biology (39.84%)
- Transcription factor (27.34%)
What were the highlights of his more recent work (between 2016-2021)?
- HDAC6 (25.78%)
- Cell biology (44.53%)
- Acetylation (23.44%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include HDAC6, Cell biology, Acetylation, Biophysics and T cell.
Patrick Matthias combines subjects such as Virus, Virology, Pharmacology and Sensory system with his study of HDAC6.
His Cell biology research is multidisciplinary, incorporating elements of Histone deacetylase, Histone deacetylase 2, Ubiquitin and Transcription factor.
His Transcription factor study combines topics from a wide range of disciplines, such as Remyelination and Germinal center.
His research combines Tubulin deacetylation and Acetylation.
His studies in Biophysics integrate themes in fields like Binding domain, Tubulin deacetylase activity and Tubulin, Microtubule.
Between 2016 and 2021, his most popular works were:
- Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner (73 citations)
- Acetylation of intrinsically disordered regions regulates phase separation. (69 citations)
- Acetylation of intrinsically disordered regions regulates phase separation. (69 citations)
In his most recent research, the most cited papers focused on:
- Gene
- DNA
- Transcription factor
Patrick Matthias mainly focuses on HDAC6, Cell biology, Acetylation, In vitro and Biophysics.
His HDAC6 study is concerned with the field of Histone deacetylase as a whole.
His studies link Cell growth with Cell biology.
His Acetylation research includes themes of RNA Helicase A and Organelle.
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