D-Index & Metrics Best Publications
Molecular Biology
Switzerland
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 92 Citations 37,295 213 World Ranking 405 National Ranking 5

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in Switzerland Leader Award

1991 - Member of Academia Europaea

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Gene expression

Molecular biology, Transcription factor, Promoter, Enhancer and Transcription are his primary areas of study. Walter Schaffner has researched Molecular biology in several fields, including Gene expression, DNA methylation, Gene, Regulation of gene expression and CpG site. His work on DNA-binding protein as part of general Transcription factor research is frequently linked to Histone octamer, bridging the gap between disciplines.

Walter Schaffner combines subjects such as Sequence motif, Reporter gene and Cell biology with his study of Promoter. His research investigates the connection between Enhancer and topics such as Regulatory sequence that intersect with issues in Binding protein and Histone H2B. The concepts of his Transcription study are interwoven with issues in Complementary DNA, TATA box and Octamer transcription factor.

His most cited work include:

  • Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells (3875 citations)
  • A rapid, sensitive, and specific method for the determination of protein in dilute solution (2237 citations)
  • A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus (1120 citations)

What are the main themes of his work throughout his whole career to date?

Walter Schaffner focuses on Molecular biology, Enhancer, Transcription factor, Gene and Genetics. The study incorporates disciplines such as DNA, DNA-binding protein, Transfection, Promoter and Transcription in addition to Molecular biology. His biological study spans a wide range of topics, including Reporter gene and Regulatory sequence.

His study in Enhancer is interdisciplinary in nature, drawing from both Regulation of gene expression, Immunoglobulin heavy chain and Cell biology. The Cell biology study combines topics in areas such as RNA polymerase II and General transcription factor. His work focuses on many connections between Transcription factor and other disciplines, such as Metallothionein, that overlap with his field of interest in Mutant.

He most often published in these fields:

  • Molecular biology (51.14%)
  • Enhancer (32.42%)
  • Transcription factor (31.05%)

What were the highlights of his more recent work (between 2003-2016)?

  • Transcription factor (31.05%)
  • Genetics (30.14%)
  • Cell biology (26.94%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Transcription factor, Genetics, Cell biology, Gene and Molecular biology. His studies in Transcription factor integrate themes in fields like Amino acid, Homeostasis, Mutant, Reporter gene and Metallothionein. His Cell biology study incorporates themes from Ecology, Rodent, Carcinogenesis, Transcription and Zinc finger transcription factor.

As part of one scientific family, Walter Schaffner deals mainly with the area of Gene, narrowing it down to issues related to the Serine, and often General transcription factor. His Molecular biology study incorporates themes from Plasma protein binding, Zinc finger, DNA-binding protein, Enhancer and Oligonucleotide. The various areas that Walter Schaffner examines in his Enhancer study include Promoter and Metal regulatory transcription factor 1.

Between 2003 and 2016, his most popular works were:

  • The taste of heavy metals: gene regulation by MTF-1. (205 citations)
  • Copper homeostasis in eukaryotes: Teetering on a tightrope (173 citations)
  • A Recent Evolutionary Change Affects a Regulatory Element in the Human FOXP2 Gene (139 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary areas of study are Transcription factor, Metallothionein, Cell biology, Molecular biology and Regulation of gene expression. His study looks at the intersection of Transcription factor and topics like Homeostasis with Copper toxicity and Botany. Walter Schaffner is doing genetic studies as part of his Gene and Biochemistry and Metallothionein investigations.

His Gene study necessitates a more in-depth grasp of Genetics. His research in Molecular biology intersects with topics in Enhancer, DNA-binding protein and Gene family. The Enhancer study which covers Promoter that intersects with Enhancer trap.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

Edgar Schreiber;Patrick Matthias;Michael M. Müller;Walter Schaffner.
Nucleic Acids Research (1989)

4849 Citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

W. Schaffner;C. Weissmann.
Analytical Biochemistry (1973)

2960 Citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

Julian Banerji;Sandro Rusconi;Walter Schaffner.
Cell (1981)

1993 Citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

Michael Boshart;Frank Weber;Gerhard Jahn;Karoline Dorsch-Häsler.
Cell (1985)

1775 Citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

Julian Banerji;Laura Olson;Walter Schaffner.
Cell (1983)

1720 Citations

Transcriptional activation modulated by homopolymeric glutamine and proline stretches.

Hans-Peter Gerber;Katja Seipel;Oleg Georgiev;Manuela Höfferer.
Science (1994)

746 Citations

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.

S. M. M. Iguchi-Ariga;W. Schaffner.
Genes & Development (1989)

706 Citations

Enhancers and eukaryotic gene transcription

Edgar Serfling;Maria Jasin;Walter Schaffner.
Trends in Genetics (1985)

699 Citations

The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

R Heuchel;F Radtke;O Georgiev;G Stark.
The EMBO Journal (1994)

593 Citations

A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells.

Michael M. Müller;Siegfried Ruppert;Walter Schaffner;Patrick Matthias.
Nature (1988)

524 Citations

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