Walter Schaffner

Research.com Recognitions

• 2026 - Research.com Molecular Biology in Switzerland Leader Award
• 2025 - Research.com Molecular Biology in Switzerland Leader Award
• 2023 - Research.com Molecular Biology in Switzerland Leader Award
• 1991 - Member of Academia Europaea

Overview

Best Publications

• Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

  Edgar Schreiber;Patrick Matthias;Michael M. Müller;Walter Schaffner

  4880
  Citations

• A rapid, sensitive, and specific method for the determination of protein in dilute solution

  W. Schaffner;C. Weissmann

  2983
  Citations

• Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

  Julian Banerji;Sandro Rusconi;Walter Schaffner

  2162
  Citations

• A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

  Michael Boshart;Frank Weber;Gerhard Jahn;Karoline Dorsch-Häsler

  1814
  Citations

• A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

  Julian Banerji;Laura Olson;Walter Schaffner

  1758
  Citations

• Transcriptional activation modulated by homopolymeric glutamine and proline stretches.

  Hans-Peter Gerber;Katja Seipel;Oleg Georgiev;Manuela Höfferer

  766
  Citations

• CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.

  S. M. M. Iguchi-Ariga;W. Schaffner

  729
  Citations

• Enhancers and eukaryotic gene transcription

  Edgar Serfling;Maria Jasin;Walter Schaffner

  712
  Citations

• The transcription factor MTF-1 is essential for basal and heavy metal-induced metallothionein gene expression.

  R Heuchel;F Radtke;O Georgiev;G Stark

  615
  Citations

• A cloned octamer transcription factor stimulates transcription from lymphoid-specific promoters in non-B cells.

  Michael M. Müller;Siegfried Ruppert;Walter Schaffner;Patrick Matthias

  524
  Citations

• Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

  F Radtke;R Heuchel;O Georgiev;M Hergersberg

  485
  Citations

• Different activation domains stimulate transcription from remote ('enhancer') and proximal ('promoter') positions.

  K Seipel;O Georgiev;W Schaffner

  456
  Citations

• A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

  Didier Picard;Walter Schaffner

  456
  Citations

• The taste of heavy metals: gene regulation by MTF-1.

  Viola Günther;Uschi Lindert;Walter Schaffner

  406
  Citations

• A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs.

  Jean de Villiers;Walter Schaffner

  406
  Citations

• Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated.

  M Höller;G Westin;J Jiricny;W Schaffner

  396
  Citations

• Molecular Genetic Analyses of the Tyrolean Ice Man

  Oliva Handt;Martin Richards;Marion Trommsdorff;Christian Kilger

  384
  Citations

• Transcriptional Repression by RING Finger Protein TIF1β That Interacts with the KRAB Repressor Domain of KOX1

  P Moosmann;O Georgiev;B Le Douarin;J P Bourquin

  380
  Citations

• Direct transfer of cloned genes from bacteria to mammalian cells

  Walter Schaffner

  379
  Citations

• The Transcription Factor Mtf-1 Is Essential for Basal and Heavy Metal-Induced Metallothionein-I Gene-Expression

  F. Radtke;R. Heuchel;O. Georgiev;G. Stark

  0
  Citations