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Molecular Biology

D-Index
49
Citations
12568
World Ranking
2609
National Ranking
176

Overview

Michael Boshart is affiliated with Ludwig-Maximilians-Universität München in Germany. Their research interests primarily focus on molecular biology and medicine, with a significant emphasis on parasitology and biochemical pathways related to Trypanosoma species and Leishmaniasis.

The scientist has published extensively in fields including Epidemiology, Molecular Biology, Physiology, Public Health, Environmental and Occupational Health, and Plant Science.

Main topics of their work cover:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Biochemical and Molecular Research
  • Lysosomal Storage Disorders Research
  • Signaling Pathways in Disease
  • Calcium signaling and nucleotide metabolism
  • Adenosine and Purinergic Signaling

Michael Boshart frequently publishes in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Pathogens
  • eLife
  • Nature Communications
  • Frontiers in Cellular and Infection Microbiology

Frequent coauthors collaborating with Boshart include:

  • Sabine Bachmaier
  • Frédéric Bringaud
  • Esben Lorentzen
  • George B. Githure
  • Ana Brennand

Among several publications, notable recent papers are:

  • A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission, 2022, Nature Communications
  • Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline, 2021, PLoS Pathogens
  • Novel kinetoplastid-specific cAMP binding proteins identified by RNAi screening for cAMP resistance in Trypanosoma brucei, 2023, Frontiers in Cellular and Infection Microbiology
  • The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei, 2020, Biochimica et Biophysica Acta (BBA) - Bioenergetics
  • Efficient flavinylation of glycosomal fumarate reductase by its own ApbE domain in Trypanosoma brucei, 2021, FEBS Journal

Best Publications

  • A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

    M. Boshart;Lutz Gissmann;H. Ikenberg;A. Kleinheinz

  • A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

    Michael Boshart;Frank Weber;Gerhard Jahn;Karoline Dorsch-Häsler

  • Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene.

    Hans Michael Jantzen;Uwe Strähle;Bernd Gloss;Francis Stewart

  • Hydrodynamic Flow-Mediated Protein Sorting on the Cell Surface of Trypanosomes

    Markus Engstler;Markus Engstler;Thomas Pfohl;Stephan Herminghaus;Michael Boshart

  • Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.

    Mark Nichols;Falk Weih;Wolfgang Schmid;Carol DeVack

  • Differentiation of African trypanosomes is controlled by a density sensing mechanism which signals cell cycle arrest via the cAMP pathway

    Erik Vassella;Birgit Reuner;Barbara Yutzy;Michael Boshart

  • Presence of human papillomavirus in genital tumors.

    Lutz Gissmann;Michael Boshart;Matthias Dürst;Hans Ikenberg

  • SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

    Nils C. Gassen;Daniela Niemeyer;Doreen Muth;Victor M. Corman

  • Reporter constructs with low background activity utilizing the cat gene.

    Michael Boshart;Michael Klüppel;Andrea Schmidt;Günther Schütz

  • Human papillomaviruses in Buschke-Löwenstein tumors: physical state of the DNA and identification of a tandem duplication in the noncoding region of a human papillomavirus 6 subtype.

    M Boshart;H zur Hausen

  • Kinetics of endocytosis and recycling of the GPI-anchored variant surface glycoprotein in Trypanosoma brucei.

    Markus Engstler;Lutz Thilo;Frank Weise;Christoph G. Grünfelder

  • Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes.

    Siegfried Ruppert;Timothy J. Cole;Michael Boshart;Erika Schmid

  • Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements.

    Doris Nitsch;Michael Boshart;Michael Boshart;Günther Schütz

  • The tissue-specific extinguisher locus TSE1 encodes a regulatory subunit of cAMP-Dependent protein kinase

    Michael Boshart;Falk Weih;Mark Nichols;Günther Schütz

  • Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei

    Markus Engstler;Michael Boshart

  • Stage-specific Differences in Cell Cycle Control in Trypanosoma brucei Revealed by RNA Interference of a Mitotic Cyclin

    Tansy C. Hammarton;Jade Clark;Fiona Douglas;Michael Boshart

  • Two genetically defined trans-acting loci coordinately regulate overlapping sets of liver-specific genes

    Siegfried Ruppert;Michael Boshart;Franz X. Bosch;Wolfgang Schmid

  • Cell density triggers slender to stumpy differentiation of Trypanosoma brucei bloodstream forms in culture.

    Birgit Reuner;Erik Vassella;Barbara Yutzy;Michael Boshart

  • A cyclic AMP response element mediates repression of tyrosine aminotransferase gene transcription by the tissue-specific extinguisher locus Tse-1

    Michael Boshart;Falk Weih;Andrea Schmidt;R.E.Keith Fournier

  • Phosphorylation of CREB affects its binding to high and low affinity sites

    Mark Nichols;Falk Weih;Wolfgang Schmid;Carol DeVack

Frequent Co-Authors

Frédéric Bringaud
Frédéric Bringaud University of Bordeaux
Jean-Charles Portais
Jean-Charles Portais Federal University of Toulouse Midi-Pyrénées
Frank Weber
Frank Weber HEMAP AG
Günther Schütz
Günther Schütz German Cancer Research Center
Walter Schaffner
Walter Schaffner University of Zurich
Gerhard Jahn
Gerhard Jahn University of Tübingen
Bernhard Fleckenstein
Bernhard Fleckenstein University of Erlangen-Nuremberg
Michael P. Barrett
Michael P. Barrett University of Glasgow
Uwe Strähle
Uwe Strähle Karlsruhe Institute of Technology
Aloysius G.M. Tielens
Aloysius G.M. Tielens Erasmus University Rotterdam

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