World's Best Scientists 2026 revealed!
Marcello Maggiolini

Marcello Maggiolini

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
22767
World Ranking
3029
National Ranking
56

Medicine

D-Index
86
Citations
22933
World Ranking
14284
National Ranking
546

Overview

Marcello Maggiolini is affiliated with the University of Calabria in Italy and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research encompasses several subfields including molecular biology, oncology, genetics, cancer research, and immunology.

The scientist has explored a range of main topics in their work, such as:

  • Estrogen and related hormone effects
  • Cancer cells and metastasis
  • Cytokine signaling pathways and interactions
  • Cancer, hypoxia, and metabolism
  • Advanced glycation end products research
  • Metabolism, diabetes, and cancer
  • Hippo pathway signaling and YAP/TAZ

Marcello Maggiolini has contributed to notable peer-reviewed publications. Recent key papers include:

  • "The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives" (2020) published in Cancers
  • "IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells" (2020) published in Cells
  • "The IL1β-IL1R Signaling Is Involved in the Stimulatory Effects Triggered by Hypoxia in Breast Cancer Cells and Cancer-Associated Fibroblasts (CAFs)" (2020) published in Journal of Experimental & Clinical Cancer Research
  • "Focal Adhesion Kinase (FAK)-Hippo/YAP Transduction Signaling Mediates the Stimulatory Effects Exerted by S100A8/A9-RAGE System in Triple-Negative Breast Cancer (TNBC)" (2022) published in Journal of Experimental & Clinical Cancer Research
  • "Cancer Associated Fibroblasts: Role in Breast Cancer and Potential as Therapeutic Targets" (2020) published in Expert Opinion on Therapeutic Targets

The scientist's frequent collaborators include:

  • Rosamaria Lappano
  • Marianna Talia
  • Francesca Cirillo
  • Antonino Belfiore
  • Domenica Scordamaglia

Many of Marcello Maggiolini's works have appeared in the following publication venues:

  • Journal of Translational Medicine
  • Cells
  • Journal of Experimental & Clinical Cancer Research
  • Cancers
  • International Journal of Molecular Sciences

Best Publications

  • G protein-coupled receptors: novel targets for drug discovery in cancer

    Rosamaria Lappano;Marcello Maggiolini

  • The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17beta-estradiol and phytoestrogens in breast cancer cells.

    Marcello Maggiolini;Adele Vivacqua;Giovanna Fasanella;Anna Grazia Recchia

  • G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells.

    Lidia Albanito;Antonio Madeo;Rosamaria Lappano;Adele Vivacqua

  • The unfolding stories of GPR30, a new membrane-bound estrogen receptor

    Marcello Maggiolini;Didier Picard

  • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells.

    Adele Vivacqua;Daniela Bonofiglio;Anna Grazia Recchia;Anna Maria Musti

  • Mechanisms of estrogen signaling and gene expression via GPR30.

    Eric R. Prossnitz;Marcello Maggiolini

  • A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

    Dina Bellizzi;Giuseppina Rose;Paola Cavalcante;Giuseppina Covello

  • Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF

    Deo Prakash Pandey;Rosamaria Lappano;Lidia Albanito;Antonio Madeo

  • 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30.

    Adele Vivacqua;Daniela Bonofiglio;Lidia Albanito;Antonio Madeo

  • p27Kip1-stathmin interaction influences sarcoma cell migration and invasion

    Gustavo Baldassarre;Barbara Belletti;Milena S. Nicoloso;Monica Schiappacassi

  • Leptin Induces, via ERK1/ERK2 Signal, Functional Activation of Estrogen Receptor α in MCF-7 Cells

    Stefania Catalano;Loredana Mauro;Stefania Marsico;Cinzia Giordano

  • Insulin Receptor Isoforms in Physiology and Disease: An Updated View.

    Antonino Belfiore;Roberta Malaguarnera;Veronica Vella;Michael C Lawrence;Michael C Lawrence

  • Role of Phosphatidylinositol 3-Kinase-Akt Pathway in Nucleophosmin/Anaplastic Lymphoma Kinase-mediated Lymphomagenesis

    Artur Slupianek;Margaret Nieborowska-Skorska;Grazyna Hoser;Andrea Morrione

  • Bisphenol A induces gene expression changes and proliferative effects through GPER in breast cancer cells and cancer-associated fibroblasts.

    Marco Pupo;Assunta Pisano;Rosamaria Lappano;Maria Francesca Santolla

  • Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

    Andrea Morrione;Barbara Valentinis;Shi-qiong Xu;Gladys Yumet

  • The Grb10/Nedd4 Complex Regulates Ligand-Induced Ubiquitination and Stability of the Insulin-Like Growth Factor I Receptor

    Andrea Vecchione;Adriano Marchese;Pauline Henry;Daniela Rotin

  • Estrogen receptor alpha mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells.

    Marcello Maggiolini;Daniela Bonofiglio;Stefania Marsico;Maria Luisa Panno

  • Twenty years of the G protein-coupled estrogen receptor GPER: Historical and personal perspectives.

    Matthias Barton;Edward J. Filardo;Stephen J. Lolait;Peter Thomas

  • HIF-1α/GPER signaling mediates the expression of VEGF induced by hypoxia in breast cancer associated fibroblasts (CAFs)

    Ernestina Marianna De Francesco;Rosamaria Lappano;Maria Francesca Santolla;Stefania Marsico

  • A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK

    Xiaodong Feng;Xiaodong Feng;Nadia Arang;Damiano Cosimo Rigiracciolo;Damiano Cosimo Rigiracciolo;Joo Sang Lee;Joo Sang Lee

Frequent Co-Authors

Sebastiano Andò
Sebastiano Andò University of Calabria
Didier Picard
Didier Picard University of Geneva
Stefania Catalano
Stefania Catalano University of Calabria
Eric R. Prossnitz
Eric R. Prossnitz University of New Mexico
Pasquale Longo
Pasquale Longo University of Salerno
J. Silvio Gutkind
J. Silvio Gutkind University of California, San Diego
Federica Sotgia
Federica Sotgia University of Salford
Michael P. Lisanti
Michael P. Lisanti University of Salford
Pablo Tamayo
Pablo Tamayo University of California, San Diego
Giuseppe Passarino
Giuseppe Passarino University of Calabria

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