Costantino Pitzalis

Overview

Best Publications

• Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

  Fan Zhang;Kevin Wei;Kamil Slowikowski;Chamith Y Fonseka

  1397
  Citations

• Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions.

  Robert Haas;Joanne Smith;Vidalba Rocher-Ros;Suchita Nadkarni

  773
  Citations

• Ectopic lymphoid-like structures in infection, cancer and autoimmunity

  Costantino Pitzalis;Gareth Wyn Jones;Michele Bombardieri;Simon Arnett Jones

  723
  Citations

• Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis.

  Stefano Alivernini;Lucy MacDonald;Aziza Elmesmari;Samuel Finlay

  657
  Citations

• Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium

  Frances Humby;Michele Bombardieri;Antonio Manzo;Stephen Kelly

  576
  Citations

• Mesenchymal multipotency of adult human periosteal cells demonstrated by single‐cell lineage analysis

  Cosimo De Bari;Francesco Dell'Accio;Johan Vanlauwe;Jeroen Eyckmans

  526
  Citations

• Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring.

  Valentina Pucino;Valentina Pucino;Michelangelo Certo;Michelangelo Certo;Vinay Bulusu;Danilo Cucchi

  488
  Citations

• A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumor necrosis factor, IL-1, or lipopolysaccharide.

  S M Wellicome;M H Thornhill;C Pitzalis;D S Thomas

  391
  Citations

• Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

  Myles J. Lewis;Michael R. Barnes;Michael R. Barnes;Kevin Blighe;Katriona Goldmann

  382
  Citations

• Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes

  Unknown

  348
  Citations

• Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis.

  Sarah E. Headland;Hefin R. Jones;Lucy V. Norling;Andrew Kim

  324
  Citations

• Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

  Frances Humby;Myles Lewis;Nandhini Ramamoorthi;Jason A Hackney

  313
  Citations

• The role of TNF‐α in the pathogenesis of inflammation and joint destruction in rheumatoid arthritis (RA): a study using a human RA/SCID mouse chimera

  H Matsuno;K Yudoh;R Katayama;F Nakazawa

  299
  Citations

• Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjögren's syndrome

  F Barone;M Bombardieri;A Manzo;Mark Blades

  294
  Citations

• Randomized Controlled Trial of Rituximab and Cost-Effectiveness Analysis in Treating Fatigue and Oral Dryness in Primary Sjögren's Syndrome.

  Simon J. Bowman;Colin C. Everett;John L. O'Dwyer;Paul Emery

  294
  Citations

• Systematic microanatomical analysis of CXCL13 and CCL21 in situ production and progressive lymphoid organization in rheumatoid synovitis.

  Antonio Manzo;Samantha Paoletti;Maresa Carulli;Mark C Blades

  288
  Citations

• Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

  Simon Rauber;Markus Luber;Stefanie Weber;Lisa Maul

  286
  Citations

• Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis

  Francesco Ciccia;Michele Bombardieri;Alfonso Principato;AnnaRita Giardina

  284
  Citations

• Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial

  Frances Humby;Frances Humby;Patrick Durez;Patrick Durez;Maya H Buch;Maya H Buch;Myles J Lewis;Myles J Lewis

  281
  Citations

• The preferential accumulation of helper-inducer T lymphocytes in inflammatory lesions: evidence for regulation by selective endothelial and homotypic adhesion.

  Costantino Pitzalis;Gabrielle Kingsley;Dorian Haskard;Gabriel Panayi

  281
  Citations

• In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses.

  Hayley G. Evans;Nicola J. Gullick;Stephen Kelly;Costantino Pitzalis

  259
  Citations

• CXCL13, CCL21, and CXCL12 expression in salivary glands of patients with Sjögren's syndrome and MALT lymphoma: Association with reactive and malignant areas of lymphoid organization

  Francesca Barone;Michele Bombardieri;Manuela Maria Rosado;Peter Roger Morgan

  258
  Citations