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Biology and Biochemistry

D-Index
49
Citations
11582
World Ranking
17903
National Ranking
796

Overview

Jean-Charles Portais is affiliated with the Federal University of Toulouse Midi-Pyrénées in France. Their research activity spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with significant contributions in molecular biology and physiology. The scientific work reflects a focus on microbial metabolic engineering, trypanosoma species, metabolism, biochemical and molecular research, gene regulatory networks, mitochondrial function, and metabolomics.

The scientist's recent publications include several papers across notable international journals. These include:

  • "Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia," 2021, The Journal of Experimental Medicine
  • "Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis," 2021, Cell Reports
  • "Control and regulation of acetate overflow in Escherichia coli," 2021, eLife
  • "Extracellular ATP and CD39 Activate cAMP-Mediated Mitochondrial Stress Response to Promote Cytarabine Resistance in Acute Myeloid Leukemia," 2020, Cancer Discovery
  • "MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle," 2022, Biochimica et Biophysica Acta (BBA) - Bioenergetics

Frequent co-authors working with Jean-Charles Portais include Pierre Millard, Edern Cahoreau, Floriant Bellvert, Erika Pineda, and Frédéric Bringaud. These collaborations indicate ongoing research partnerships contributing to various aspects of metabolic and molecular biology studies.

Publication venues prominent in this scientist's record are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS Biology
  • Analytical Chemistry
  • The Journal of Experimental Medicine
  • Cell Reports

The main fields of study for Jean-Charles Portais include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of study consist of:

  • Molecular Biology
  • Physiology
  • Epidemiology
  • Cancer Research
  • Rehabilitation

The primary research topics investigated include:

  • Microbial Metabolic Engineering and Bioproduction
  • Trypanosoma species research and implications
  • Adipose Tissue and Metabolism
  • Biochemical and Molecular Research
  • Gene Regulatory Network Analysis
  • Mitochondrial Function and Pathology
  • Metabolomics and Mass Spectrometry Studies

Best Publications

  • Strigolactone inhibition of shoot branching

    Victoria Gomez-Roldan;Victoria Gomez-Roldan;Soraya Fermas;Philip B. Brewer;Virginie Puech-Pagès;Virginie Puech-Pagès

  • Strigolactones stimulate arbuscular mycorrhizal fungi by activating mitochondria.

    Arnaud Besserer;Virginie Puech-Pagès;Patrick Kiefer;Victoria Gomez-Roldan

  • Chemotherapy Resistant Human Acute Myeloid Leukemia Cells are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism

    Thomas Farge;Thomas Farge;Estelle saland;Estelle saland;Fabienne de Toni;Fabienne de Toni;Nesrine Aroua;Nesrine Aroua

  • Sampling for metabolome analysis of microorganisms.

    Christoph J Bolten;Patrick Kiefer;Fabien Letisse;Jean-Charles Portais

  • Demonstration of the ethylmalonyl-CoA pathway by using 13C metabolomics

    Rémi Peyraud;Patrick Kiefer;Philipp Christen;Stephane Massou

  • IsoCor: correcting MS data in isotope labeling experiments.

    Pierre Millard;Fabien Letisse;Serguei Sokol;Jean-Charles Portais

  • Engineering Escherichia coli for methanol conversion

    Jonas E N Müller;Fabian Meyer;Boris Litsanov;Patrick Kiefer

  • Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway.

    Brice Enjalbert;Pierre Millard;Mickael Dinclaux;Jean-Charles Portais

  • Genome-scale reconstruction and system level investigation of the metabolic network of Methylobacterium extorquens AM1

    Rémi Peyraud;Kathrin Schneider;Patrick Kiefer;Stéphane Massou;Stéphane Massou;Stéphane Massou

  • Metabolic footprint of epiphytic bacteria on Arabidopsis thaliana leaves.

    Florian Ryffel;Eric J N Helfrich;Patrick Kiefer;Lindsay Peyriga;Lindsay Peyriga;Lindsay Peyriga

  • Mitochondrial Energetic and AKT Status Mediate Metabolic Effects and Apoptosis of Metformin in Human Leukemic Cells

    S Scotland;E Saland;E Saland;N Skuli;N Skuli;F de Toni;F de Toni

  • High mTORC1 activity drives glycolysis addiction and sensitivity to G6PD inhibition in acute myeloid leukemia cells

    L Poulain;P Sujobert;F Zylbersztejn;F Zylbersztejn;S Barreau

  • Multiple formate dehydrogenase enzymes in the facultative methylotroph Methylobacterium extorquens AM1 are dispensable for growth on methanol

    Ludmila Chistoserdova;Markus Laukel;Markus Laukel;Jean-Charles Portais;Julia A. Vorholt

  • Metabolic flux determination in C6 glioma cells using carbon-13 distribution upon [1-13C]glucose incubation.

    Jean-Charles Portais;Ronny Schuster;Michel Merle;Paul Canioni

  • Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53

    Romain Riscal;Emilie Schrepfer;Giuseppe Arena;Madi Y. Cissé

  • Quantitative metabolome analysis using liquid chromatography-high-resolution mass spectrometry

    Patrick Kiefer;Jean-Charles Portais;Jean-Charles Portais;Jean-Charles Portais;Julia A. Vorholt

  • MetExplore: collaborative edition and exploration of metabolic networks

    Ludovic Cottret;Clément Frainay;Maxime Chazalviel;Floréal Cabanettes

  • Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate

    Lennart Leßmeier;Johannes Pfeifenschneider;Marc Carnicer;Stephanie Heux

  • NMR and microbiology: from physiology to metabolomics

    Jean Philippe Grivet;Anne Marie Delort;Jean Charles Portais

  • Determination of carbon labeling distribution of intracellular metabolites from single fragment ions by ion chromatography tandem mass spectrometry.

    Patrick Kiefer;Cécile Nicolas;Fabien Letisse;Jean-Charles Portais

Frequent Co-Authors

Christoph Wittmann
Christoph Wittmann Saarland University
Frédéric Bringaud
Frédéric Bringaud University of Bordeaux
Christian Recher
Christian Recher Federal University of Toulouse Midi-Pyrénées
Volker F. Wendisch
Volker F. Wendisch Bielefeld University
Guillaume Bécard
Guillaume Bécard Paul Sabatier University
Muriel Cocaign-Bousquet
Muriel Cocaign-Bousquet Federal University of Toulouse Midi-Pyrénées
Michael Boshart
Michael Boshart Ludwig-Maximilians-Universität München
Pierre Monsan
Pierre Monsan Institut National des Sciences Appliquées de Toulouse
Guy Lippens
Guy Lippens Federal University of Toulouse Midi-Pyrénées

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