What is he best known for?
The fields of study he is best known for:
Ralph Mazitschek mainly investigates Biochemistry, Cellular differentiation, Cell biology, HDAC6 and In vivo.
His work on Histone and Histone deacetylase as part of general Biochemistry study is frequently connected to Functional group, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
The concepts of his Cellular differentiation study are interwoven with issues in Amino acid, Signal transduction and Halofuginone.
Ralph Mazitschek has included themes like Experimental autoimmune encephalomyelitis, Autoimmunity and Starvation response in his Signal transduction study.
Within one scientific family, Ralph Mazitschek focuses on topics pertaining to Cell cycle under Cell biology, and may sometimes address concerns connected to Proliferating cell nuclear antigen.
As a part of the same scientific study, he usually deals with the In vivo, concentrating on Pharmacology and frequently concerns with Systemic administration and Mode of action.
His most cited work include:
- HDAC2 negatively regulates memory formation and synaptic plasticity (1178 citations)
- Chemical phylogenetics of histone deacetylases (548 citations)
- Chemical phylogenetics of histone deacetylases (548 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Cancer research, Cell biology, Histone deacetylase and HDAC6 are his primary areas of study.
His Biochemistry research integrates issues from Plasmodium falciparum and In vivo.
His studies deal with areas such as Amino acid and Small molecule as well as Cell biology.
His Histone deacetylase research includes elements of Molecular biology, Epigenetics and Acetylation.
His HDAC6 research is multidisciplinary, incorporating perspectives in Deacetylase activity and Immunology.
The Halofuginone study combines topics in areas such as Cellular differentiation and Drug resistance.
He most often published in these fields:
- Biochemistry (36.84%)
- Cancer research (20.10%)
- Cell biology (25.36%)
What were the highlights of his more recent work (between 2016-2021)?
- Biochemistry (36.84%)
- Pharmacology (17.70%)
- Cancer research (20.10%)
In recent papers he was focusing on the following fields of study:
Ralph Mazitschek focuses on Biochemistry, Pharmacology, Cancer research, Histone deacetylase and In vivo.
He performs integrative study on Biochemistry and Prolyl tRNA synthetase.
His Pharmacology study incorporates themes from Cell, Obesity, Celastrol and HDAC6.
His Cancer research study combines topics from a wide range of disciplines, such as Cell growth, Downregulation and upregulation, TFEB, Neurodegeneration and Epigenetics.
His work focuses on many connections between Histone deacetylase and other disciplines, such as Acetylation, that overlap with his field of interest in Neuropharmacology, Lupus nephritis and Endocrinology.
His In vivo study which covers Ubiquitin that intersects with Cancer cell.
Between 2016 and 2021, his most popular works were:
- HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy. (67 citations)
- Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models. (48 citations)
- HDAC3 regulates DNMT1 expression in multiple myeloma: therapeutic implications. (36 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cancer research, Pharmacology, Histone deacetylase, Cell growth and Kinase.
In his study, which falls under the umbrella issue of Cancer research, Growth inhibition, Signal transduction, Gene knockdown and Carcinogenesis is strongly linked to Downregulation and upregulation.
His Pharmacology study integrates concerns from other disciplines, such as Acetylation, CREB, Hydroxamic acid, HDAC6 and Histone.
The concepts of his Histone deacetylase study are interwoven with issues in Spindle apparatus, Deacetylase activity, Paclitaxel and Neuropharmacology.
Ralph Mazitschek has researched Kinase in several fields, including Protein kinase B, Phosphorylation and PI3K/AKT/mTOR pathway.
The subject of his PI3K/AKT/mTOR pathway research is within the realm of Biochemistry.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
