What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Neuroscience, Genetics, Histone, Small molecule and Cell biology.
His Neuroscience study integrates concerns from other disciplines, such as Alzheimer's disease, Neurodegeneration and Pharmacology.
His work on FMR1, Epigenetics, Exome and Allele as part of his general Genetics study is frequently connected to Multifactorial Inheritance, thereby bridging the divide between different branches of science.
In the subject of general Histone, his work in Histone deacetylase 2 is often linked to Epigenetics of cocaine addiction, thereby combining diverse domains of study.
His Small molecule research includes themes of Immunology, Drug repositioning, Zebrafish, Computational biology and Drug discovery.
Stephen J. Haggarty combines subjects such as Drug action, Disease, Function and Molecular targets with his study of Computational biology.
His most cited work include:
- The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease (3268 citations)
- The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease (3268 citations)
- Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen (1436 citations)
What are the main themes of his work throughout his whole career to date?
Stephen J. Haggarty spends much of his time researching Cell biology, Neuroscience, Histone deacetylase, Epigenetics and Small molecule.
The study incorporates disciplines such as Molecular biology and Neurodegeneration in addition to Cell biology.
His work deals with themes such as Induced pluripotent stem cell and Drug discovery, which intersect with Neuroscience.
His Histone deacetylase research focuses on subjects like Pharmacology, which are linked to Kinase and In vitro.
Stephen J. Haggarty has included themes like Histone and Memory consolidation in his Epigenetics study.
His research links Computational biology with Small molecule.
He most often published in these fields:
- Cell biology (29.85%)
- Neuroscience (29.48%)
- Histone deacetylase (13.43%)
What were the highlights of his more recent work (between 2018-2021)?
- Cell biology (29.85%)
- Neuroscience (29.48%)
- Neurodegeneration (6.34%)
In recent papers he was focusing on the following fields of study:
Cell biology, Neuroscience, Neurodegeneration, Induced pluripotent stem cell and Frontotemporal dementia are his primary areas of study.
His study in Cell biology is interdisciplinary in nature, drawing from both Histone deacetylase, microRNA, Peptide and Tauopathy.
His studies deal with areas such as Psychiatric Disease, Circular RNA, Gene expression and Cereblon as well as Neuroscience.
As a part of the same scientific family, he mostly works in the field of Neurodegeneration, focusing on Activator and, on occasion, Gliosis.
Stephen J. Haggarty studied Frontotemporal dementia and Tau protein that intersect with Cell, Drug discovery, Disease mechanisms, Disease etiology and DNA ligase.
His Psychological repression study is concerned with the field of Gene as a whole.
Between 2018 and 2021, his most popular works were:
- Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models (74 citations)
- Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia (41 citations)
- A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy (31 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cell biology, Drug discovery, Neural stem cell, Neurodegeneration and Tauopathy.
His Cell biology research incorporates themes from Autophagy and Downregulation and upregulation, Gene.
His Drug discovery research is multidisciplinary, incorporating elements of Ex vivo, Computational biology and Drug.
His work carried out in the field of Computational biology brings together such families of science as Precision medicine, Stem cell, Disease, Translational science and Cell type.
His research integrates issues of Cancer research, Neurite, Corticobasal degeneration, Induced pluripotent stem cell and Neurogenesis in his study of Neural stem cell.
His work in Tauopathy covers topics such as Tau protein which are related to areas like Frontotemporal dementia, Cell and Neuroscience.
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