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Edward M. Scolnick

Edward M. Scolnick

D-Index & Metrics

Biology and Biochemistry

D-Index
121
Citations
78357
World Ranking
596
National Ranking
381

Medicine

D-Index
121
Citations
79036
World Ranking
3538
National Ranking
1948

Research.com Recognitions

  • 1996 - Member of the National Academy of Medicine (NAM)
  • 1984 - Member of the National Academy of Sciences

Overview

Edward M. Scolnick is affiliated with the Broad Institute in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with particular attention to genetics, molecular biology, physiology, organic chemistry, and oncology as subfields of study.

Their work addresses a variety of topics, including:

  • Glycosylation and Glycoproteins Research
  • Genetics and Neurodevelopmental Disorders
  • Genetic Associations and Epidemiology
  • Carbohydrate Chemistry and Synthesis
  • Lysosomal Storage Disorders Research
  • Drug Transport and Resistance Mechanisms
  • Trace Elements in Health

Recent papers authored or co-authored by Edward M. Scolnick include:

  • Rare coding variants in ten genes confer substantial risk for schizophrenia (2022, Nature)
  • Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues (2022, Nature Communications)
  • Glycobiology and schizophrenia: a biological hypothesis emerging from genomic research (2020, Molecular Psychiatry)
  • Aberrant glycosylation in schizophrenia: a review of 25 years of post-mortem brain studies (2020, Molecular Psychiatry)
  • The schizophrenia risk locus in SLC39A8 alters brain metal transport and plasma glycosylation (2020, Scientific Reports)

They frequently publish in these venues:

  • Molecular Psychiatry
  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Communications

Collaborators often include:

  • Jordan W. Smoller
  • Sarah Williams
  • Richard D. Cummings
  • Robert G. Mealer
  • Giulio Genovese

Awards received by Edward M. Scolnick include membership in notable academies:

  • Member of the National Academy of Medicine (NAM), 1996
  • Member of the National Academy of Sciences, 1984

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

    Shaun M. Purcell;Shaun M. Purcell;Naomi R. Wray;Jennifer L. Stone;Jennifer L. Stone;Peter M. Visscher

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Active human immunodeficiency virus protease is required for viral infectivity.

    Nancy E. Kohl;Emilio A. Emini;William A. Schleif;Lenora J. Davis

  • De novo mutations in schizophrenia implicate synaptic networks

    Menachem Fromer;Andrew Pocklington;David Kavanagh;Hywel John Williams

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Mechanism of activation of a human oncogene.

    Clifford J. Tabin;Scott M. Bradley;Cornelia I. Bargmann;Robert A. Weinberg

  • A polygenic burden of rare disruptive mutations in schizophrenia

    Shaun M Purcell;Jennifer L Moran;Menachem Fromer;Douglas Ruderfer

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

    Manuel A R Ferreira;Michael C O'Donovan;Yan A Meng;Ian R Jones

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors

    Mark S. Kramer;Neal Cutler;John Feighner;Ram Shrivastava

  • Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family.

    M E Furth;L J Davis;B Fleurdelys;E M Scolnick

  • Growth of factor-dependent hemopoietic precursor cell lines.

    T M Dexter;J Garland;D Scott;E Scolnick

  • Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

    Christian R Marshall;Daniel P Howrigan;Daniel P Howrigan;Daniele Merico;Bhooma Thiruvahindrapuram

  • The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

    Ronald W. Ellis;Deborah DeFeo;Thomas Y. Shih;Matthew A. Gonda

  • Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor.

    NE Kohl;SD Mosser;SJ deSolms;EA Giuliani

  • Whole-genome association study of bipolar disorder

    P Sklar;J W Smoller;J Fan;J Fan;M A R Ferreira

Frequent Co-Authors

Shaun Purcell
Shaun Purcell Harvard Medical School
Pamela Sklar
Pamela Sklar Icahn School of Medicine at Mount Sinai
Jordan W. Smoller
Jordan W. Smoller Harvard University
Douglas M. Ruderfer
Douglas M. Ruderfer Vanderbilt University Medical Center
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill
Sarah E. Bergen
Sarah E. Bergen Karolinska Institute
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Derek W. Morris
Derek W. Morris University of Galway
Stephan Ripke
Stephan Ripke Massachusetts General Hospital

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