D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 147 Citations 84,982 415 World Ranking 137 National Ranking 106

Research.com Recognitions

Awards & Achievements

2014 - Member of the National Academy of Sciences

2008 - Fellow of the American Academy of Arts and Sciences

1997 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Timothy J. Mitchison mainly investigates Cell biology, Microtubule, Mitosis, Cytoskeleton and Actin. His biological study spans a wide range of topics, including Spindle apparatus, Actin remodeling, MDia1, Kinetochore and Arp2/3 complex. His Microtubule research includes elements of Microtubule nucleation and Centrosome.

His work in Mitosis addresses issues such as Cell cycle, which are connected to fields such as Interphase. His study explores the link between Cytoskeleton and topics such as Chemotaxis that cross with problems in Polymerization. His study in Actin is interdisciplinary in nature, drawing from both Cytoplasm, Cytokinesis, Cell cortex, Intracellular and Motility.

His most cited work include:

  • Dynamic instability of microtubule growth (2471 citations)
  • MICROTUBULE POLYMERIZATION DYNAMICS (1949 citations)
  • Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury (1753 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Microtubule, Mitosis, Spindle apparatus and Tubulin. His research in Cell biology is mostly focused on Actin. His Microtubule research incorporates elements of Astral microtubules, Microtubule nucleation, Aster and Centrosome.

His Mitosis research incorporates themes from Cell division, Cytokinesis, Chromatin, Cell cycle and Interphase. His work deals with themes such as Metaphase, Microtubule polymerization and Anaphase, which intersect with Spindle apparatus. His studies examine the connections between Cytoskeleton and genetics, as well as such issues in Biophysics, with regards to Biochemistry and Microtubule plus-end.

He most often published in these fields:

  • Cell biology (75.86%)
  • Microtubule (49.14%)
  • Mitosis (32.33%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cell biology (75.86%)
  • Microtubule (49.14%)
  • Mitosis (32.33%)

In recent papers he was focusing on the following fields of study:

Timothy J. Mitchison mostly deals with Cell biology, Microtubule, Mitosis, Biophysics and Aster. The study incorporates disciplines such as Spindle apparatus, Cell division, Cytokinesis and Microtubule nucleation in addition to Cell biology. His Spindle apparatus study combines topics in areas such as Metaphase and Anaphase.

His research integrates issues of Xenopus, Cytoplasm, Centrosome and Cytoskeleton in his study of Microtubule. His Mitosis research is multidisciplinary, incorporating perspectives in Cancer research, Chromosome segregation, Cancer cell, Chromatin and Spindle organization. His Biophysics research is multidisciplinary, incorporating elements of Nucleocytoplasmic Transport, Microtubule plus-end, Macromolecule and Protein filament.

Between 2013 and 2021, his most popular works were:

  • The bacterial cell division proteins FtsA and FtsZ self-organize into dynamic cytoskeletal patterns (253 citations)
  • Hydrolysis of 2′3′-cGAMP by ENPP1 and design of nonhydrolyzable analogs (176 citations)
  • Amyloid-like Self-Assembly of a Cellular Compartment (166 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His main research concerns Cell biology, Microtubule, Mitosis, Cell division and Aster. The concepts of his Cell biology study are interwoven with issues in Xenopus and Cytokinesis. Timothy J. Mitchison is interested in Tubulin, which is a field of Microtubule.

Timothy J. Mitchison has included themes like Spindle apparatus, Cancer research, Cell cycle, Anaphase and Interphase in his Mitosis study. His Cell division study incorporates themes from GTPase and Cytoskeleton. His research in Aster intersects with topics in Biophysics, Cleavage and Protein filament.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Dynamic instability of microtubule growth

Tim Mitchison;Marc Kirschner.
Nature (1984)

3849 Citations

MICROTUBULE POLYMERIZATION DYNAMICS

Arshad Desai;Timothy J. Mitchison.
Annual Review of Cell and Developmental Biology (1997)

3090 Citations

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

Alexei Degterev;Zhihong Huang;Michael Boyce;Yaqiao Li.
Nature Chemical Biology (2005)

2739 Citations

Actin-Based Cell Motility and Cell Locomotion

T.J Mitchison;L.P Cramer.
Cell (1996)

2252 Citations

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer;Tarun M. Kapoor;Stephen J. Haggarty;Stephen J. Haggarty;Randall W. King.
Science (1999)

2146 Citations

A chemical method for fast and sensitive detection of DNA synthesis in vivo

Adrian Salic;Timothy J. Mitchison.
Proceedings of the National Academy of Sciences of the United States of America (2008)

1989 Citations

Beyond self-assembly: from microtubules to morphogenesis

Marc Kirschner;Tim Mitchison.
Cell (1986)

1601 Citations

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

Philipp Niethammer;Clemens Grabher;Clemens Grabher;A. Thomas Look;Timothy J. Mitchison.
Nature (2009)

1524 Citations

Dissecting Temporal and Spatial Control of Cytokinesis with a Myosin II Inhibitor

Aaron F. Straight;Amy Cheung;John Limouze;Irene Chen.
Science (2003)

1493 Citations

Cytoskeletal dynamics and nerve growth.

Tim Mitchison;Marc Kirschner.
Neuron (1988)

1053 Citations

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