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Molecular Biology

D-Index
86
Citations
29081
World Ranking
822
National Ranking
434

Overview

Arshad Desai is affiliated with the University of California, San Diego in the United States. Their research primarily falls within the broad field of Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology and Cell Biology. Additional subfields they explore include Plant Science, Genetics, and Aging.

Their work addresses a range of scientific topics such as microtubule and mitosis dynamics, cellular transport and secretion, ubiquitin and proteasome pathways, DNA repair mechanisms, photosynthetic processes and mechanisms, genomics and chromatin dynamics, as well as chromosomal and genetic variations.

Desai has contributed papers published in a variety of venues, reflecting an active engagement in current scientific discourse. Frequent publication venues include bioRxiv (Cold Spring Harbor Laboratory), The Journal of Cell Biology, UNC Libraries, Current Biology, and Science.

Recent papers highlight diverse research interests, including:

  • Control of cell proliferation by memories of mitosis, 2024, Science
  • Spindle assembly checkpoint activation and silencing at kinetochores, 2021, Seminars in Cell and Developmental Biology
  • TRIM37 controls cancer-specific vulnerability to PLK4 inhibition, 2020, Nature
  • Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome, 2020, The Journal of Cell Biology
  • A tripartite mechanism catalyzes Mad2-Cdc20 assembly at unattached kinetochores, 2020, Science

Frequent coauthors include Karen Oegema, Pablo Lara-González, Midori Ohta, Kevin D. Corbett, and Franz Meitinger. This network reflects collaboration across multiple studies and projects.

Best Publications

  • MICROTUBULE POLYMERIZATION DYNAMICS

    Arshad Desai;Timothy J. Mitchison

  • The Conserved KMN Network Constitutes the Core Microtubule-Binding Site of the Kinetochore

    Iain M. Cheeseman;Joshua S. Chappie;Elizabeth M. Wilson-Kubalek;Arshad Desai

  • Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project

    Mark B. Gerstein;Zhi John Lu;Eric L. Van Nostrand;Chao Cheng

  • Molecular architecture of the kinetochore–microtubule interface

    Iain M. Cheeseman;Arshad Desai

  • Kin I Kinesins Are Microtubule-Destabilizing Enzymes

    Arshad Desai;Suzie Verma;Timothy J. Mitchison;Claire E. Walczak

  • XKCM1: A Xenopus Kinesin-Related Protein That Regulates Microtubule Dynamics during Mitotic Spindle Assembly

    Claire E Walczak;Timothy J Mitchison;Arshad Desai

  • The spindle: a dynamic assembly of microtubules and motors.

    Torsten Wittmann;Anthony Hyman;Arshad Desai

  • The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres.

    Masahiro Okada;Iain M. Cheeseman;Tetsuya Hori;Katsuya Okawa

  • A Molecular View of Kinetochore Assembly and Function.

    Andrea Musacchio;Arshad Desai

  • Functional analysis of kinetochore assembly in Caenorhabditis elegans.

    Karen Oegema;Arshad Desai;Sonja Rybina;Matthew Kirkham

  • A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

    Iain M. Cheeseman;Sherry Niessen;Scott Anderson;Francie Hyndman

  • PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression.

    Wen Liu;Bogdan Tanasa;Bogdan Tanasa;Oksana V. Tyurina;Tian Yuan Zhou

  • Reversible centriole depletion with an inhibitor of Polo-like kinase 4

    Yao Liang Wong;John V. Anzola;Robert L. Davis;Michelle Yoon

  • Protein architecture of the human kinetochore microtubule attachment site.

    Xiaohu Wan;Ryan P. O'Quinn;Heather L. Pierce;Ajit P. Joglekar

  • Fluorescent speckle microscopy, a method to visualize the dynamics of protein assemblies in living cells

    Clare M. Waterman-Storer;Arshad Desai;J. Chloe Bulinski;E.D. Salmon

  • A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans

    Anjon Audhya;Francie Hyndman;Ian X. McLeod;Amy S. Maddox

  • Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System

    Stefano Santaguida;Amelia Richardson;Divya Ramalingam Iyer;Ons M'Saad

  • Centriole assembly requires both centriolar and pericentriolar material proteins.

    Alexander Dammermann;Thomas Müller-Reichert;Laurence Pelletier;Bianca Habermann

  • The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro.

    Arshad Desai;Andrew Murray;Timothy J. Mitchison;Claire E. Walczak

  • Broad chromosomal domains of histone modification patterns in C. elegans

    Tao Liu;Andreas Rechtsteiner;Thea A. Egelhofer;Anne Vielle

Frequent Co-Authors

Karen Oegema
Karen Oegema University of California, San Diego
Fabio Piano
Fabio Piano New York University
Susan Strome
Susan Strome University of California, Santa Cruz
Anthony A. Hyman
Anthony A. Hyman Max Planck Institute of Molecular Cell Biology and Genetics
Timothy J. Mitchison
Timothy J. Mitchison Harvard University
Julie Ahringer
Julie Ahringer University of Cambridge
Steven Henikoff
Steven Henikoff Fred Hutchinson Cancer Research Center
Michael Snyder
Michael Snyder Stanford University
Chao Cheng
Chao Cheng Baylor College of Medicine

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