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Molecular Biology
UK
2026
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Molecular Biology

D-Index
134
Citations
66018
World Ranking
162
National Ranking
9

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2025 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Molecular Biology in United Kingdom Leader Award
  • 2013 - Fellow of the Royal Society, United Kingdom
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2002 - Fellow of the Royal Society of Edinburgh
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

William C. Earnshaw is affiliated with the University of Edinburgh in the United Kingdom. Their research focuses primarily on the field of Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Cell Biology, Plant Science, Genetics, and Ecology. The main topics of their work include Genomics and Chromatin Dynamics, RNA Research and Splicing, Microtubule and mitosis dynamics, Chromosomal and Genetic Variations, RNA modifications and cancer, DNA and Nucleic Acid Chemistry, and CRISPR and Genetic Engineering.

Earnshaw has published extensively in various scientific venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Trends in Cell Biology
  • Journal of Cell Science
  • Nature Communications
  • UNC Libraries

Their recent papers reflect ongoing research in cell biology and chromatin dynamics. Notable publications are:

  • "Vertebrate centromeres in mitosis are functionally bipartite structures stabilized by cohesin," 2024, Cell
  • "The intrinsically disorderly story of Ki-67," 2021, Open Biology
  • "Mitotic chromosomes," 2021, Seminars in Cell and Developmental Biology
  • "CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly," 2020, Journal of Cell Science
  • "Common Fragile Sites Are Characterized by Faulty Condensin Loading after Replication Stress," 2020, Cell Reports

Co-authorship patterns reveal collaboration with a number of frequent scientific partners. These include:

  • Natalia Y. Kochanova
  • Maria Alba Abad
  • Kumiko Samejima
  • Itaru Samejima
  • Geert J.P.L. Kops

Throughout their career, William C. Earnshaw has been recognized by several professional societies. Their awards and honors comprise:

  • Fellow of the Royal Society, United Kingdom, 2013
  • Fellow of the American Association for the Advancement of Science (AAAS), 2007
  • Fellow of the Royal Society of Edinburgh, 2002
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis

    William C. Earnshaw;Luis M. Martins;Scott H. Kaufmann

  • Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

    Y. A. Lazebnik;S. H. Kaufmann;S. Desnoyers;G. G. Poirier

  • Induction of apoptosis by cancer chemotherapy.

    Scott H. Kaufmann;William C. Earnshaw

  • The cellular geography of aurora kinases.

    Mar Carmena;William C. Earnshaw

  • Structure and Function in the Nucleus

    Angus I. Lamond;William C. Earnshaw

  • Two distinct pathways leading to nuclear apoptosis.

    Santos A. Susin;Eric Daugas;Luigi Ravagnan;Kumiko Samejima

  • Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma.

    William C. Earnshaw;Naomi Rothfield

  • Chromosomal passengers: conducting cell division

    Sandrine Ruchaud;Mar Carmena;William C. Earnshaw

  • The Chromosomal Passenger Complex (CPC): From Easy Rider to the Godfather of Mitosis

    Mar Carmena;Michael Wheelock;Hironori Funabiki;William C. Earnshaw

  • Topoisomerase II is a structural component of mitotic chromosome scaffolds

    William C. Earnshaw;Brian Halligan;Carol A. Cooke;Margarete M S Heck

  • Caspases and caspase inhibitors.

    Pascal Villa;Scott H. Kaufmann;William C. Earnshaw

  • Nuclear changes in apoptosis.

    William C Earnshaw

  • Chromosomal passengers and the (aurora) ABCs of mitosis.

    Richard R. Adams;Mar Carmena;William C. Earnshaw

  • Modulation of cell death by Bcl-XL through caspase interaction.

    Rollie J. Clem;Rollie J. Clem;Emily H.-Y. Cheng;Emily H.-Y. Cheng;Christopher L. Karp;David G. Kirsch

  • Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

    Yuri A. Lazebnik;Atsushi Takahashi;Robert D. Moir;Robert D. Goldman

  • Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation.

    Richard R. Adams;Helder Maiato;William C. Earnshaw;Mar Carmena

  • A pathway for mitotic chromosome formation

    Johan H. Gibcus;Kumiko Samejima;Anton Goloborodko;Itaru Samejima

  • Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis.

    Atsushi Takahashi;Emad S. Alnemri;Yuri A. Lazebnik;Yuri A. Lazebnik;Teresa Fernandes-Alnemri

  • DNA packaging by the double-stranded DNA bacteriophages

    William C. Earnshaw;Sherwood R. Casjens

  • Localization of topoisomerase II in mitotic chromosomes.

    W C Earnshaw;M M Heck

Frequent Co-Authors

Vladimir Larionov
Vladimir Larionov National Institutes of Health
Hiroshi Masumoto
Hiroshi Masumoto Kazusa DNA Research Institute
Juri Rappsilber
Juri Rappsilber Technical University of Berlin
Naomi F. Rothfield
Naomi F. Rothfield University of Connecticut
Tatsuo Fukagawa
Tatsuo Fukagawa Osaka University
Timothy Kottke
Timothy Kottke Mayo Clinic
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Helder Maiato
Helder Maiato University of Porto
Chris P. Ponting
Chris P. Ponting University of Edinburgh

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