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D-Index
46
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8439
World Ranking
4163
National Ranking
183

Overview

Hiroshi Masumoto is affiliated with the Kazusa DNA Research Institute in Japan, focusing on research within the field of Biochemistry, Genetics, and Molecular Biology. Their work spans multiple subfields, including Molecular Biology, Plant Science, Pharmacology, Computational Theory and Mathematics, and Genetics.

The scientist's research topics cover diverse areas such as Pharmacogenetics and Drug Metabolism, Chromosomal and Genetic Variations, Genomics and Chromatin Dynamics, Computational Drug Discovery Methods, CRISPR and Genetic Engineering, Genomic variations and chromosomal abnormalities, and RNA modifications and cancer.

Recent publications by Hiroshi Masumoto include the following papers:

  • CENP-B creates alternative epigenetic chromatin states permissive for CENP-A or heterochromatin assembly (2020), published in Journal of Cell Science
  • Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation (2021), published in Current Biology
  • H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory (2020), published in Journal of Cell Science
  • Human artificial chromosome: Chromatin assembly mechanisms and CENP-B (2020), published in Experimental Cell Research
  • Successful treatment of recurrent small cell carcinoma of urinary bladder with pembrolizumab (2020), published in IJU Case Reports

Hiroshi Masumoto frequently collaborates with colleagues including Paul Erhardt, Kenneth Bachmann, Donald Birkett, Michael Boberg, and Nicholas Bodor.

The scientist's publications have predominantly appeared in venues such as:

  • IUPAC Standards Online
  • Journal of Cell Science
  • Experimental Cell Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Current Biology

Best Publications

  • A human centromere antigen (CENP-B) interacts with a short specific sequence in alphoid DNA, a human centromeric satellite.

    H Masumoto;H Masukata;Y Muro;N Nozaki

  • Construction of YAC-based mammalian artificial chromosomes.

    Masashi Ikeno;Brenda Grimes;Tuneko Okazaki;Tuneko Okazaki;Megumi Nakano

  • CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA.

    Jun-ichirou Ohzeki;Megumi Nakano;Teruaki Okada;Hiroshi Masumoto

  • Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore.

    Jan H Bergmann;Mariluz Gómez Rodríguez;Nuno M C Martins;Hiroshi Kimura

  • CENP-B controls centromere formation depending on the chromatin context.

    Teruaki Okada;Jun-ichirou Ohzeki;Megumi Nakano;Kinya Yoda

  • Centromere protein B assembles human centromeric alpha-satellite DNA at the 17-bp sequence, CENP-B box.

    Y Muro;H Masumoto;K Yoda;N Nozaki

  • Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers

    Megumi Nakano;Stefano Cardinale;Vladimir N. Noskov;Reto Gassmann

  • The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein

    Natalay Kouprina;Adam Pavlicek;N. Keith Collins;Megumi Nakano

  • Distribution of CENP-B boxes reflected in CREST centromere antigenic sites on long-range α-satellite DNA arrays of human chromosome 21

    Masashi Ikeno;Hiroshi Masumoto;Tuneko Okazaki

  • Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase

    Tomohiro Hayakawa;Tokuko Haraguchi;Hiroshi Masumoto;Yasushi Hiraoka

  • The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells

    Yuuki Obata;Yukihiro Furusawa;Takaho A Endo;Jafar Sharif

  • Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly.

    Jun-ichirou Ohzeki;Jan H Bergmann;Natalay Kouprina;Vladimir N Noskov

  • Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes

    H T Tran;N P Degtyareva;N N Koloteva;A Sugino

  • A human centromere protein, CENP-B, has a DNA binding domain containing four potential alpha helices at the NH2 terminus, which is separable from dimerizing activity.

    K Yoda;K Kitagawa;H Masumoto;Y Muro

  • Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere–kinetochore complexes

    Naoko Sugata;Shulan Li;William C. Earnshaw;Tim J. Yen

  • Alphoid satellite DNA is tightly associated with centromere antigens in human chromosomes throughout the cell cycle.

    Hiroshi Masumoto;Kenji Sugimoto;Tuneko Okazaki

  • Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice

    Maki Suzuki;Yoko Mizutani-Koseki;Yu-ichi Fujimura;Hiro Miyagishima

  • Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function

    Jan H. Bergmann;Julia N. Jakubsche;Nuno M. Martins;Alexander Kagansky

  • 3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin.

    Daniel G. Booth;Alison J. Beckett;Oscar Molina;Itaru Samejima

  • The role of CENP-B and α-satellite DNA: de novo assembly and epigenetic maintenance of human centromeres

    Hiroshi Masumoto;Megumi Nakano;Jun-ichirou Ohzeki

Frequent Co-Authors

Vladimir Larionov
Vladimir Larionov National Institutes of Health
William C. Earnshaw
William C. Earnshaw University of Edinburgh
Tuneko Okazaki
Tuneko Okazaki Fujita Health University
Hiroshi Kimura
Hiroshi Kimura Tokyo Institute of Technology
Mitsuo Oshimura
Mitsuo Oshimura Tottori University
Haruhiko Koseki
Haruhiko Koseki RIKEN Center for Integrative Medical Sciences
Akio Sugino
Akio Sugino Osaka University
Tatsuo Fukagawa
Tatsuo Fukagawa Osaka University
Howard J. Cooke
Howard J. Cooke University of Edinburgh
Hitoshi Kurumizaka
Hitoshi Kurumizaka University of Tokyo

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