His primary areas of study are Molecular biology, DNA replication, DNA polymerase II, Biochemistry and Eukaryotic DNA replication. His work in Molecular biology tackles topics such as Mutant which are related to areas like Mutation. His DNA polymerase II research includes elements of DNA polymerase delta, DNA repair and DNA polymerase.
His study looks at the intersection of DNA polymerase and topics like DNA clamp with DNA polymerase I, 3'-5' Exonuclease and Klenow fragment. Eukaryotic DNA replication is often connected to Origin of replication in his work. He has researched Origin recognition complex in several fields, including Replication factor C, Control of chromosome duplication, Chromatin, S phase and Cell biology.
Akio Sugino mainly focuses on Molecular biology, DNA replication, DNA polymerase II, DNA polymerase and DNA polymerase delta. The concepts of his Molecular biology study are interwoven with issues in Saccharomyces cerevisiae, Biochemistry, DNA, Chromatin and Gene. His DNA replication research integrates issues from Replication protein A and DNA repair.
The study incorporates disciplines such as DNA clamp, Polymerase, DNA polymerase mu, DNA polymerase epsilon and Primase in addition to DNA polymerase II. His DNA polymerase research includes themes of Molecular cloning and DNA polymerase I. The various areas that Akio Sugino examines in his Control of chromosome duplication study include Cell biology and Origin recognition complex, Eukaryotic DNA replication.
Molecular biology, DNA replication, Eukaryotic DNA replication, DNA polymerase II and Control of chromosome duplication are his primary areas of study. His Molecular biology study combines topics in areas such as Chromatin, Polymerase, DNA, DNA polymerase and DNA replication factor CDT1. His DNA replication research is classified as research in Genetics.
The DNA polymerase II study combines topics in areas such as DNA polymerase delta and DNA clamp. His study in Control of chromosome duplication is interdisciplinary in nature, drawing from both Origin of replication and Cell biology. His Cell biology research incorporates themes from Replication protein A and Origin recognition complex.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme
Akio Sugino;Craig L. Peebles;Kenneth N. Kreuzer;Nicholas R. Cozzarelli.
Proceedings of the National Academy of Sciences of the United States of America (1977)
Energy coupling in DNA gyrase and the mechanism of action of novobiocin
Akio Sugino;N. Patrick Higgins;Patrick O. Brown;Craig L. Peebles.
Proceedings of the National Academy of Sciences of the United States of America (1978)
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains.
Reiji Okazaki;Tuneko Okazaki;Kiwako Sakabe;Kazunori Sugimoto.
Proceedings of the National Academy of Sciences of the United States of America (1968)
GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast
Yuko Takayama;Yoichiro Kamimura;Mariko Okawa;Sachiko Muramatsu.
Genes & Development (2003)
A third essential DNA polymerase in S. cerevisiae.
Alan Morrison;Hiroyuki Araki;Alan B. Clark;Robert K. Hamatake.
Eukaryotic DNA polymerases: proposal for a revised nomenclature.
Peter M J Burgers;Eugene V. Koonin;Elspeth Bruford;Luis Blanco.
Journal of Biological Chemistry (2001)
Mcm2 is a target of regulation by Cdc7–Dbf4 during the initiation of DNA synthesis
Ming Lei;Yasuo Kawasaki;Michael R. Young;Makoto Kihara.
Genes & Development (1997)
A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.
K Kitada;A L Johnson;L H Johnston;A Sugino.
Molecular and Cellular Biology (1993)
Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint
Hiroyuki Araki;Sun-Hee Leem;Amornrat Phongdara;Akio Sugino.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.
Alan Morrison;Juliette B. Bell;Thomas A. Kunkel;Akio Sugino.
Proceedings of the National Academy of Sciences of the United States of America (1991)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: