What is he best known for?
The fields of study he is best known for:
His primary areas of study are Molecular biology, DNA replication, DNA polymerase II, Biochemistry and Eukaryotic DNA replication.
His work in Molecular biology tackles topics such as Mutant which are related to areas like Mutation.
His DNA polymerase II research includes elements of DNA polymerase delta, DNA repair and DNA polymerase.
His study looks at the intersection of DNA polymerase and topics like DNA clamp with DNA polymerase I, 3'-5' Exonuclease and Klenow fragment.
Eukaryotic DNA replication is often connected to Origin of replication in his work.
He has researched Origin recognition complex in several fields, including Replication factor C, Control of chromosome duplication, Chromatin, S phase and Cell biology.
His most cited work include:
- Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme (568 citations)
- Eukaryotic DNA polymerases: proposal for a revised nomenclature. (310 citations)
- GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast (308 citations)
What are the main themes of his work throughout his whole career to date?
Akio Sugino mainly focuses on Molecular biology, DNA replication, DNA polymerase II, DNA polymerase and DNA polymerase delta.
The concepts of his Molecular biology study are interwoven with issues in Saccharomyces cerevisiae, Biochemistry, DNA, Chromatin and Gene.
His DNA replication research integrates issues from Replication protein A and DNA repair.
The study incorporates disciplines such as DNA clamp, Polymerase, DNA polymerase mu, DNA polymerase epsilon and Primase in addition to DNA polymerase II.
His DNA polymerase research includes themes of Molecular cloning and DNA polymerase I.
The various areas that Akio Sugino examines in his Control of chromosome duplication study include Cell biology and Origin recognition complex, Eukaryotic DNA replication.
He most often published in these fields:
- Molecular biology (76.92%)
- DNA replication (58.65%)
- DNA polymerase II (46.15%)
What were the highlights of his more recent work (between 2003-2009)?
- Molecular biology (76.92%)
- DNA replication (58.65%)
- Eukaryotic DNA replication (31.73%)
In recent papers he was focusing on the following fields of study:
Molecular biology, DNA replication, Eukaryotic DNA replication, DNA polymerase II and Control of chromosome duplication are his primary areas of study.
His Molecular biology study combines topics in areas such as Chromatin, Polymerase, DNA, DNA polymerase and DNA replication factor CDT1.
His DNA replication research is classified as research in Genetics.
The DNA polymerase II study combines topics in areas such as DNA polymerase delta and DNA clamp.
His study in Control of chromosome duplication is interdisciplinary in nature, drawing from both Origin of replication and Cell biology.
His Cell biology research incorporates themes from Replication protein A and Origin recognition complex.
Between 2003 and 2009, his most popular works were:
- Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts. (70 citations)
- The phosphorylated C‐terminal domain of Xenopus Cut5 directly mediates ATR‐dependent activation of Chk1 (60 citations)
- Reconstitution of Saccharomyces Cerevisiae Prereplicative Complex Assembly in Vitro (46 citations)
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