His primary scientific interests are in DNA gyrase, Biochemistry, DNA supercoil, DNA and Topoisomerase. His DNA gyrase research is multidisciplinary, incorporating elements of Antibacterial agent, Novobiocin, Enzyme, Stereochemistry and Quinolone. The study incorporates disciplines such as ATP hydrolysis and Mode of action in addition to Stereochemistry.
His DNA supercoil research is multidisciplinary, incorporating perspectives in Molecular biology, Circular bacterial chromosome and Topoisomerase-II Inhibitor. Anthony Maxwell focuses mostly in the field of DNA, narrowing it down to matters related to Transcription and, in some cases, Polymerase and Gene knockout. His Topoisomerase research focuses on A-DNA and how it connects with Duplex, Molecular mass, Dimer and Bacteriophage Mu.
Anthony Maxwell focuses on DNA gyrase, DNA, Biochemistry, DNA supercoil and Topoisomerase. Anthony Maxwell has included themes like Molecular biology, Stereochemistry, Quinolone and Enzyme in his DNA gyrase study. His work deals with themes such as Cleavage and Protein subunit, which intersect with DNA.
In the field of Biochemistry, his study on Binding site, Topoisomerase-II Inhibitor, ATPase and Mutant overlaps with subjects such as DNA clamp. His research integrates issues of ATP hydrolysis, Biophysics, Circular bacterial chromosome, Replisome and Novobiocin in his study of DNA supercoil. Anthony Maxwell combines subjects such as Topoisomer, Topoisomerase IV and A-DNA with his study of Topoisomerase.
DNA gyrase, DNA, DNA supercoil, Topoisomerase and Biophysics are his primary areas of study. His study in DNA gyrase is interdisciplinary in nature, drawing from both Stereochemistry, In vivo and Enzyme. His research in DNA intersects with topics in Molecular recognition, Antimicrobial and Cleavage.
His work carried out in the field of DNA supercoil brings together such families of science as Salmonella enterica, Function, Bacteria, Novobiocin and Microbiology. His Topoisomerase study combines topics in areas such as Antibiotics, Antibiotic resistance, Quinolone and Computational biology. His study explores the link between Biochemistry and topics such as Mycobacterium smegmatis that cross with problems in ATP hydrolysis, Pentapeptide repeat and ATPase.
Anthony Maxwell mainly focuses on DNA gyrase, DNA, Topoisomerase, Stereochemistry and Antibiotics. His research on DNA gyrase frequently links to adjacent areas such as Microcin. Anthony Maxwell focuses mostly in the field of Topoisomerase, narrowing it down to topics relating to Cleavage and, in certain cases, Adenosine, Mutant, Enzyme, Isomerase and Topoisomerase inhibitor.
His biological study spans a wide range of topics, including Catalytic cycle, Base pair and A-DNA. His Escherichia coli study combines topics from a wide range of disciplines, such as DNA supercoil, rpoN, rpoS and Quinolone. The various areas that Anthony Maxwell examines in his DNA supercoil study include DNA Replication Fork, Biophysics, Replisome, Chromosome and Transcription.
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DNA Gyrase: Structure and Function
Richard J. Reece;Anthony Maxwell.
Critical Reviews in Biochemistry and Molecular Biology (1991)
Crystal structure of an N-terminal fragment of the DNA gyrase B protein.
Dale B. Wigley;Gideon J. Davies;Eleanor J. Dodson;Anthony Maxwell.
Crystal structure of the breakage-reunion domain of DNA gyrase
Joo H. Morais Cabral;Andrew P. Jackson;Clare V. Smith;Nita Shikotra.
Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.
Frédéric Collin;Shantanu Karkare;Anthony Maxwell.
Applied Microbiology and Biotechnology (2011)
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs
Janid A. Ali;Andrew P. Jackson;Alison J. Howells;Anthony Maxwell.
THE NATURE OF INHIBITION OF DNA GYRASE BY THE COUMARINS AND THE CYCLOTHIALIDINES REVEALED BY X-RAY CRYSTALLOGRAPHY
R. J. Lewis;O. M. P. Singh;C. V. Smith;T. Skarzynski.
The EMBO Journal (1996)
Mechanistic Aspects of DNA Topoisomerases
Anthony Maxwell;Martin Gellert.
Advances in Protein Chemistry (1986)
A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA.
Subray S. Hegde;Matthew W. Vetting;Matthew W. Vetting;Matthew W. Vetting;Steven L. Roderick;Steven L. Roderick;Steven L. Roderick;Lesley A. Mitchenall;Lesley A. Mitchenall;Lesley A. Mitchenall.
A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex.
C. J. R. Willmott;A. Maxwell.
Antimicrobial Agents and Chemotherapy (1993)
The interaction between coumarin drugs and DNA gyrase.
Molecular Microbiology (1993)
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