World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
81
Citations
18762
World Ranking
975
National Ranking
73

Overview

Anthony Maxwell is affiliated with the John Innes Centre in the United Kingdom. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant concentration in molecular biology. Other subfields include molecular medicine, toxicology, infectious diseases, and pharmacology.

The scientist's work spans several important topics, notably:

  • Cancer therapeutics and mechanisms
  • Antibiotic resistance in bacteria
  • Bioactive compounds and antitumor agents
  • DNA and nucleic acid chemistry
  • Antibiotics pharmacokinetics and efficacy
  • Tuberculosis research and epidemiology
  • Insect symbiosis and bacterial influences

Recent publications by Anthony Maxwell include:

  • "Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance," 2020, published in Molecules
  • "DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis," 2021, published in BioEssays
  • "Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides," 2021, published in Nature Communications
  • "Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds," 2021, published in Nature Communications
  • "Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa," 2023, published in Journal of Medicinal Chemistry

Frequent co-authors collaborating with Anthony Maxwell have included:

  • David M. Lawson
  • Shannon J. McKie
  • Keir C. Neuman
  • Clare E. M. Stevenson
  • Natassja G. Bush

The scientist's contributions have appeared in multiple venues, with several recurrent publication sources:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature (19 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (4 publications)
  • eLife (3 publications)
  • Nature Communications (2 publications)
  • Journal of Medicinal Chemistry (2 publications)

Best Publications

  • DNA Gyrase: Structure and Function

    Richard J. Reece;Anthony Maxwell

  • Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

    Dale B. Wigley;Gideon J. Davies;Eleanor J. Dodson;Anthony Maxwell

  • DNA gyrase as a drug target

    Anthony Maxwell

  • Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.

    Frédéric Collin;Shantanu Karkare;Anthony Maxwell

  • Crystal structure of the breakage-reunion domain of DNA gyrase

    Joo H. Morais Cabral;Andrew P. Jackson;Clare V. Smith;Nita Shikotra

  • The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs

    Janid A. Ali;Andrew P. Jackson;Alison J. Howells;Anthony Maxwell

  • THE NATURE OF INHIBITION OF DNA GYRASE BY THE COUMARINS AND THE CYCLOTHIALIDINES REVEALED BY X-RAY CRYSTALLOGRAPHY

    R. J. Lewis;O. M. P. Singh;C. V. Smith;T. Skarzynski

  • A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA.

    Subray S. Hegde;Matthew W. Vetting;Matthew W. Vetting;Matthew W. Vetting;Steven L. Roderick;Steven L. Roderick;Steven L. Roderick;Lesley A. Mitchenall;Lesley A. Mitchenall;Lesley A. Mitchenall

  • Mechanistic Aspects of DNA Topoisomerases

    Anthony Maxwell;Martin Gellert

  • A single point mutation in the DNA gyrase A protein greatly reduces binding of fluoroquinolones to the gyrase-DNA complex.

    C. J. R. Willmott;A. Maxwell

  • The interaction between coumarin drugs and DNA gyrase.

    Anthony Maxwell

  • The ATP-binding site of type II topoisomerases as a target for antibacterial drugs.

    Anthony Maxwell;David M Lawson

  • Mode of Action

    A. Maxwell;S. E. Critchlow

  • Arabidopsis SPO11-2 functions with SPO11-1 in meiotic recombination.

    Nicola J. Stacey;Takashi Kuromori;Yoshitaka Azumi;Gethin Roberts

  • Quinolones: Mechanism, Lethality and Their Contributions to Antibiotic Resistance

    Natassja G Bush;Isabel Diez-Santos;Lauren R Abbott;Anthony Maxwell

  • Interaction between DNA Gyrase and Quinolones: Effects of Alanine Mutations at GyrA Subunit Residues Ser83 and Asp87

    Faye M. Barnard;Anthony Maxwell

  • The molecular basis of quinolone action

    Anthony Maxwell

  • The interaction of coumarin antibiotics with fragments of DNA gyrase B protein.

    Niall A. Gormley;George Orphanides;Andrew Meyer;Paul M. Cullis

  • Tryptic fragments of the Escherichia coli DNA gyrase A protein.

    R J Reece;A Maxwell

  • The DNA dependence of the ATPase activity of DNA gyrase.

    A Maxwell;M Gellert

Frequent Co-Authors

Martin Gellert
Martin Gellert National Institute of Diabetes and Digestive and Kidney Diseases
Dale B. Wigley
Dale B. Wigley Imperial College London
Konstantin Severinov
Konstantin Severinov Rutgers, The State University of New Jersey
David J. Sherratt
David J. Sherratt University of Oxford
Valakunja Nagaraja
Valakunja Nagaraja Indian Institute of Science
Mark J. Buttner
Mark J. Buttner Norwich Research Park
Hans-Peter Fiedler
Hans-Peter Fiedler University of Tübingen
Stephen E. Halford
Stephen E. Halford University of Bristol
Lutz Heide
Lutz Heide University of Tübingen
Keith Roberts
Keith Roberts John Innes Centre

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a career in Molecular Biology can open doors to a variety of interdisciplinary fields and specialized online degree options. Professionals interested in combining scientific knowledge with service might consider the social work online master's programs, where a background in biology can enhance roles in health advocacy or community health services.

For those seeking flexibility, especially military members and their families, military friendly colleges offer tailored support and online learning options. This can be especially beneficial for students balancing service commitments with their education.

Specialized paths such as psychology and mental health also complement a molecular biology background. Students may explore masters in psychology online or pursue clinical work through online masters in mental health counseling. These programs provide accelerated pathways for those eager to make an impact in healthcare, research, or clinical environments.

Ultimately, the flexibility of online learning and diverse career pathways ensures that molecular biology graduates can tailor their educational journey to their unique interests and goals.

Best Scientists Citing Anthony Maxwell

Trending Scientists