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Genetics

D-Index
69
Citations
14495
World Ranking
2368
National Ranking
297

Overview

Mark J. Buttner is affiliated with Norwich Research Park in the United Kingdom. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology and pharmacology. They also contribute to fields such as ecology, evolution, behavior and systematics, genetics, and radiology, nuclear medicine, and imaging.

Their published work covers a range of topics including microbial natural products and biosynthesis, bacterial genetics and biotechnology, genomics and phylogenetic studies, RNA and protein synthesis mechanisms, plant and fungal interactions, plant biochemistry and biosynthesis, and applications of machine learning in bioinformatics.

Mark J. Buttner has contributed to the following recent papers:

  • Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal, 2020, Nature Microbiology
  • When is a transcription factor a NAP?, 2020, Current Opinion in Microbiology
  • Expansion and re-classification of the extracytoplasmic function (ECF) σ factor family, 2020, Nucleic Acids Research
  • Streptomyces venezuelae NRRL B-65442: genome sequence of a model strain used to study morphological differentiation in filamentous actinobacteria, 2021, Journal of Industrial Microbiology & Biotechnology
  • Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB, 2023, Proceedings of the National Academy of Sciences

The scientist frequently publishes in several notable academic venues, including:

  • Current Opinion in Microbiology (2 publications)
  • Proceedings of the National Academy of Sciences (2 publications)
  • Journal of Allergy and Clinical Immunology (2 publications)
  • Zenodo (CERN European Organization for Nuclear Research) (2 publications)
  • Nature Microbiology (1 publication)

Mark J. Buttner collaborates regularly with a group of coauthors, with the most frequent including:

  • Matthew J. Bush (5 collaborations)
  • Govind Chandra (4 collaborations)
  • Neil A. Holmes (4 collaborations)
  • Delia Casas-Pastor (3 collaborations)
  • Raphael Müller (3 collaborations)

Best Publications

  • Streptomyces morphogenetics: dissecting differentiation in a filamentous bacterium

    Klas Flärdh;Mark J. Buttner

  • Analysis of the Streptomyces coelicolor sigE gene reveals the existence of a subfamily of eubacterial RNA polymerase sigma factors involved in the regulation of extracytoplasmic functions.

    Michael A. Lonetto;Kelly L. Brown;Kelly L. Brown;Kelly L. Brown;Kenneth E. Rudd;Mark J. Buttner;Mark J. Buttner

  • Evidence that the extracytoplasmic function sigma factor sigmaE is required for normal cell wall structure in Streptomyces coelicolor A3(2).

    Mark S. B. Paget;Mark S. B. Paget;Leony Chamberlin;Abdelmadjid Atrih;Simon J. Foster

  • Construction and characterisation of a series of multi-copy promoter-probe plasmid vectors for Streptomyces using the aminoglycoside phosphotransferase gene from Tn5 as indicator.

    J M Ward;G R Janssen;T Kieser;M J Bibb

  • Thiol-based regulatory switches.

    Mark S B Paget;Mark J Buttner

  • The SapB morphogen is a lantibiotic-like peptide derived from the product of the developmental gene ramS in Streptomyces coelicolor

    Shinya Kodani;Michael E. Hudson;Marcus C. Durrant;Mark J. Buttner

  • The chaplins: a family of hydrophobic cell-surface proteins involved in aerial mycelium formation in Streptomyces coelicolor

    Marie A. Elliot;Nitsara Karoonuthaisiri;Jianqiang Huang;Maureen J. Bibb

  • RsrA, an anti-sigma factor regulated by redox change.

    Ju‐Gyeong Kang;Mark S.B. Paget;Mark S.B. Paget;Yeong‐Jae Seok;Mi‐Young Hahn

  • σR, an RNA polymerase sigma factor that modulates expression of the thioredoxin system in response to oxidative stress in Streptomyces coelicolor A3(2)

    Mark S.B. Paget;Mark S.B. Paget;Ju‐Gyeong Kang;Jung‐Hye Roe;Mark J. Buttner;Mark J. Buttner

  • Tetrameric c-di-GMP mediates effective transcription factor dimerization to control Streptomyces development.

    Natalia Tschowri;Maria A. Schumacher;Susan Schlimpert;Naga babu Chinnam

  • The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility σ factor of B. subtilis

    Keith F. Chater;Celia J. Bruton;Kitty A. Plaskitt;Mark J. Buttner

  • Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon.

    Mark S. B. Paget;Virginie Molle;Gerald Cohen;Yair Aharonowitz

  • Cross‐regulation among disparate antibiotic biosynthetic pathways of Streptomyces coelicolor

    Jianqiang Huang;Jing Shi;Virginie Molle;Björn Sohlberg

  • Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth

    Chris D. Den Hengst;Ngat T. Tran;Maureen J. Bibb;Govind Chandra

  • The agarase gene (dagA) of Streptomyces coelicolor A3(2): nucleotide sequence and transcriptional analysis

    Mark J. Buttner;Ian M. Fearnley;Mervyn J. Bibb

  • Cloning, disruption, and transcriptional analysis of three RNA polymerase sigma factor genes of Streptomyces coelicolor A3(2).

    M J Buttner;K F Chater;M J Bibb

  • Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2)

    Matthew I. Hutchings;Paul A. Hoskisson;Govind Chandra;Mark J. Buttner

  • sigma(BldN), an extracytoplasmic function RNA polymerase sigma factor required for aerial mycelium formation in Streptomyces coelicolor A3(2).

    Maureen J. Bibb;Virginie Molle;Mark J. Buttner

  • At least three different RNA polymerase holoenzymes direct transcription of the agarase gene (dagA) of streptomyces coelicolor A3(2)

    Mark J. Buttner;Alison M. Smith;Mervyn J. Bibb

  • Developmental Regulation of Transcription of whiE, a Locus Specifying the Polyketide Spore Pigment in Streptomyces coelicolor A3(2)

    Gabriella H. Kelemen;Paul Brian;Klas Flärdh;Leony Chamberlin

Frequent Co-Authors

Kim Findlay
Kim Findlay Norwich Research Park
Keith F. Chater
Keith F. Chater Norwich Research Park
Maria A. Schumacher
Maria A. Schumacher Duke University
Mervyn J. Bibb
Mervyn J. Bibb John Innes Centre
Richard G. Brennan
Richard G. Brennan Duke University
Colin Kleanthous
Colin Kleanthous University of Oxford
Anthony Maxwell
Anthony Maxwell John Innes Centre
Gregory L. Challis
Gregory L. Challis University of Warwick
Charles J. Thompson
Charles J. Thompson University of British Columbia
Stanley N. Cohen
Stanley N. Cohen Stanford University

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