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Yasuo Ohnishi

Yasuo Ohnishi

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
9460
World Ranking
16712
National Ranking
1196

Overview

Yasuo Ohnishi is affiliated with the University of Tokyo in Japan. Their research spans multiple disciplines within biochemistry, genetics, and molecular biology, with significant contributions to medicine as well.

The primary fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of focus cover:

  • Molecular Biology
  • Pharmacology
  • Organic Chemistry
  • Materials Chemistry
  • Biotechnology

The scientist's work predominantly revolves around topics such as:

  • Microbial Natural Products and Biosynthesis
  • Genomics and Phylogenetic Studies
  • Microbial Metabolic Engineering and Bioproduction
  • Plant Biochemistry and Biosynthesis
  • Carbohydrate Chemistry and Synthesis
  • Enzyme Structure and Function
  • Cyclopropane Reaction Mechanisms

Ohnishi has published papers extensively in the following venues:

  • Angewandte Chemie International Edition
  • Bioscience Biotechnology and Biochemistry
  • ChemBioChem
  • Angewandte Chemie
  • Journal of Bacteriology

Recent papers feature notable research including:

  • Complete Biosynthetic Pathway of Alazopeptin, a Tripeptide Consisting of Two Molecules of 6-Diazo-5-oxo-l-norleucine and One Molecule of Alanine, 2021, Angewandte Chemie International Edition
  • Structural basis for selectivity in a highly reducing type II polyketide synthase, 2020, Nature Chemical Biology
  • Structural and Functional Analyses of the Tridomain-Nonribosomal Peptide Synthetase FmoA3 for 4-Methyloxazoline Ring Formation, 2021, Angewandte Chemie International Edition
  • Bacterial Avenalumic Acid Biosynthesis Includes Substitution of an Aromatic Amino Group for Hydride by Nitrous Acid Dependent Diazotization, 2022, Angewandte Chemie International Edition
  • Ultrahigh Thermoresistant Lightweight Bioplastics Developed from Fermentation Products of Cellulosic Feedstock, 2020, Advanced Sustainable Systems

The scientist frequently collaborates with other researchers, especially:

  • Yohei Katsuyama
  • Seiji Kawai
  • Takeaki Tezuka
  • Kazuo Shin-ya
  • Yoshitaka Moriwaki

Best Publications

  • Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350

    Yasuo Ohnishi;Jun Ishikawa;Hirofumi Hara;Hirokazu Suzuki

  • A new pathway for polyketide synthesis in microorganisms

    Nobutaka Funa;Yasuo Ohnishi;Isao Fujii;Masaaki Shibuya

  • The A‐factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A‐factor receptor

    Yasuo Ohnishi;Shogo Kameyama;Hiroyasu Onaka;Sueharu Horinouchi

  • AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus.

    Yasuo Ohnishi;Haruka Yamazaki;Jun-ya Kato;Ayami Tomono

  • Production of plant-specific flavanones by Escherichia coli containing an artificial gene cluster.

    Eui Il Hwang;Masafumi Kaneko;Yasuo Ohnishi;Sueharu Horinouchi

  • Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster

    Ikuo Miyahisa;Masafumi Kaneko;Nobutaka Funa;Hisashi Kawasaki

  • Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces

    Jun-ya Kato;Nobutaka Funa;Hidenori Watanabe;Yasuo Ohnishi

  • Combinatorial biosynthesis of flavones and flavonols in Escherichia coli

    Ikuo Miyahisa;Nobutaka Funa;Yasuo Ohnishi;Stefan Martens

  • Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus.

    Clyde A. Kelly;Makoto Nishiyama;Yasuo Ohnishi;Teruhiko Beppu

  • An A-factor-dependent extracytoplasmic function sigma factor (sigma(AdsA)) that is essential for morphological development in Streptomyces griseus.

    Haruka Yamazaki;Yasuo Ohnishi;Sueharu Horinouchi

  • Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces,Revealed the Extent and Complexity of the AdpA Regulatory Network

    Akiyoshi Higo;Hirofumi Hara;Sueharu Horinouchi;Yasuo Ohnishi

  • GriC and GriD constitute a carboxylic acid reductase involved in grixazone biosynthesis in Streptomyces griseus.

    Hirokazu Suzuki;Yasuo Ohnishi;Sueharu Horinouchi

  • DNA-binding specificity of AdpA, a transcriptional activator in the A-factor regulatory cascade in Streptomyces griseus.

    Haruka Yamazaki;Ayami Tomono;Yasuo Ohnishi;Sueharu Horinouchi

  • AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs.

    Akiko Tanaka;Yuji Takano;Yasuo Ohnishi;Sueharu Horinouchi

  • Crystal Structure of a γ-Butyrolactone Autoregulator Receptor Protein in Streptomyces coelicolor A3(2)

    Ryo Natsume;Yasuo Ohnishi;Toshiya Senda;Sueharu Horinouchi

  • Cinnamate:Coenzyme A Ligase from the Filamentous Bacterium Streptomyces coelicolor A3(2)

    Masafumi Kaneko;Yasuo Ohnishi;Sueharu Horinouchi

  • Properties and Substrate Specificity of RppA, a Chalcone Synthase-related Polyketide Synthase in Streptomyces griseus

    Nobutaka Funa;Yasuo Ohnishi;Yutaka Ebizuka;Sueharu Horinouchi

  • Biosynthesis of Hexahydroxyperylenequinone Melanin via Oxidative Aryl Coupling by Cytochrome P-450 in Streptomyces griseus

    Nobutaka Funa;Masanori Funabashi;Yasuo Ohnishi;Sueharu Horinouchi

  • Novel Benzene Ring Biosynthesis from C3 and C4 Primary Metabolites by Two Enzymes

    Hirokazu Suzuki;Yasuo Ohnishi;Yasuhide Furusho;Shohei Sakuda

  • Transcriptional switch on of ssgA by A-factor, which is essential for spore septum formation in Streptomyces griseus.

    Haruka Yamazaki;Yasuo Ohnishi;Sueharu Horinouchi

Frequent Co-Authors

Sueharu Horinouchi
Sueharu Horinouchi University of Tokyo
Masaru Tanokura
Masaru Tanokura University of Tokyo
Kazuo Shin-ya
Kazuo Shin-ya National Institute of Advanced Industrial Science and Technology
Norihiko Misawa
Norihiko Misawa Ishikawa Prefectural University
Kensuke Furukawa
Kensuke Furukawa Beppu University
Shigeaki Harayama
Shigeaki Harayama Chuo University
Teruhiko Beppu
Teruhiko Beppu University of Tokyo
Yutaka Ebizuka
Yutaka Ebizuka University of Tokyo
Makoto Nishiyama
Makoto Nishiyama University of Tokyo
Chiaki Ogino
Chiaki Ogino Kobe University

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