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Makoto Nishiyama

Makoto Nishiyama

University of Tokyo
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
13848
World Ranking
9730
National Ranking
653

Makoto Nishiyama publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Makoto Nishiyama sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 317 publications — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Makoto Nishiyama D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Makoto Nishiyama sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 64 D-Index — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Makoto Nishiyama is affiliated with the University of Tokyo in Japan and has contributed significantly to multiple domains within biochemistry, genetics, and molecular biology. Their work spans across subfields such as molecular biology, pharmacology, surgery, plant science, and organic chemistry.

The main research topics that characterize Nishiyama's scientific contributions include:

  • Microbial Natural Products and Biosynthesis
  • Plant biochemistry and biosynthesis
  • Genomics and Phylogenetic Studies
  • Enzyme Structure and Function
  • Microbial Metabolic Engineering and Bioproduction
  • Carbohydrate Chemistry and Synthesis
  • Spinal Fractures and Fixation Techniques

Nishiyama's publication record is distributed among various prominent scientific journals. Frequent publication venues are:

  • Journal of the American Chemical Society
  • Communications Biology
  • The Journal of General and Applied Microbiology
  • Nature Chemical Biology
  • Cell

Some of their recent papers include:

  • A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem, 2023, Nature Chemical Biology
  • Soy and Arabidopsis receptor-like kinases respond to polysaccharide signals from Spodoptera species and mediate herbivore resistance, 2020, Communications Biology
  • A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion, 2022, Cell
  • Reconstitution of a Highly Reducing Type II PKS System Reveals 6π-Electrocyclization Is Required for o-Dialkylbenzene Biosynthesis, 2021, Journal of the American Chemical Society
  • A Natural Dihydropyridazinone Scaffold Generated from a Unique Substrate for a Hydrazine-Forming Enzyme, 2022, Journal of the American Chemical Society

Collaborative work is an important feature of Nishiyama's research. Frequent co-authors include:

  • Saori Kosono
  • Tomohisa Kuzuyama
  • Ayako Yoshida
  • Takeo Tomita
  • Norihiro Isogai

Nishiyama's research contributions integrate knowledge across diverse scientific areas and emphasize enzyme structure and function, microbial metabolism, plant biochemical pathways, and carbohydrate synthesis. Their interdisciplinary approach aligns with developments in molecular biology and biochemistry, supporting various applications ranging from natural product biosynthesis to plant resistance mechanisms.

Best Publications

  • FK228 (Depsipeptide) as a Natural Prodrug That Inhibits Class I Histone Deacetylases

    Ryohei Furumai;Akihisa Matsuyama;Nobuyuki Kobashi;Kun-Hyung Lee

  • A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion.

    Kyonsoo Hong;Lindsay Hinck;Makoto Nishiyama;Mu-ming Poo

  • Calcium stores regulate the polarity and input specificity of synaptic modification.

    Makoto Nishiyama;Kyonsoo Hong;Kyonsoo Hong;Katsuhiko Mikoshiba;Mu-ming Poo

  • Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning.

    Makoto Nishiyama;Akemi Hoshino;Lily Tsai;John R. Henley

  • Calcium signalling in the guidance of nerve growth by netrin-1

    Kyonsoo Hong;Makoto Nishiyama;John Henley;Marc Tessier-Lavigne

  • Histone deacetylase as a new target for cancer chemotherapy.

    Minoru Yoshida;Ryohei Furumai;Makoto Nishiyama;Yasuhiko Komatsu

  • X-ray structure and site-directed mutagenesis of a nitrite reductase from Alcaligenes faecalis S-6: roles of two copper atoms in nitrite reduction.

    Mutsuko Kukimoto;Makoto Nishiyama;Michael E. P. Murphy;Stewart Turley

  • Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product.

    Michihiko Kobayashi;Hidenobu Komeda;Toru Nagasawa;Makoto Nishiyama

  • Primary structure of AfsR, a global regulatory protein for secondary metabolite formation in Streptomyces coelicolor A3(2)

    Sueharu Horinouchi;Morikazu Kito;Makoto Nishiyama;Kaoru Furuya

  • Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus.

    Clyde A. Kelly;Makoto Nishiyama;Yasuo Ohnishi;Teruhiko Beppu

  • Cloning and characterization of genes responsible for metabolism of nitrile compounds from Pseudomonas chlororaphis B23.

    M Nishiyama;S Horinouchi;M Kobayashi;T Nagasawa

  • Molecular cloning and characterization of a cDNA encoding ent‐cassa‐12,15‐diene synthase, a putative diterpenoid phytoalexin biosynthetic enzyme, from suspension‐cultured rice cells treated with a chitin elicitor

    Eun-Min Cho;Atsushi Okada;Hiromichi Kenmoku;Kazuko Otomo

  • Cloning, nucleotide sequence and expression in Escherichia coli of two cobalt-containing nitrile hydratase genes from Rhodococcus rhodochrous J1.

    Michihiko Kobayashi;Makoto Nishiyama;Toru Nagasawa;Sueharu Horinouchi

  • Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways.

    Georg Schendzielorz;Martin Dippong;Alexander Grünberger;Dietrich Kohlheyer

  • Catalytic roles for two water bridged residues (Asp-98 and His-255) in the active site of copper-containing nitrite reductase.

    Martin J. Boulanger;Mutsuko Kukimoto;Makoto Nishiyama;Sueharu Horinouchi

  • Primary structure of nitrile hydratase deduced from the nucleotide sequence of a Rhodococcus species and its expression in Escherichia coli

    Osamu Ikehata;Makoto Nishiyama;Sueharu Horinouchi;Teruhiko Beppu

  • A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway : a key to the evolution of amino acid biosynthesis

    Hiromi Nishida;Makoto Nishiyama;Nobuyuki Kobashi;Takehide Kosuge

  • Chemoenzymatic syntheses of prenylated aromatic small molecules using Streptomyces prenyltransferases with relaxed substrate specificities

    Takuto Kumano;Stéphane B. Richard;Joseph P. Noel;Makoto Nishiyama

  • Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source

    Saori Kosono;Masaru Tamura;Shota Suzuki;Yumi Kawamura

  • Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases

    Seung-Young Kim;Ping Zhao;Masayuki Igarashi;Ryuichi Sawa

Frequent Co-Authors

Tomohisa Kuzuyama
Tomohisa Kuzuyama University of Tokyo
Sueharu Horinouchi
Sueharu Horinouchi University of Tokyo
Teruhiko Beppu
Teruhiko Beppu University of Tokyo
Ko Okumura
Ko Okumura Juntendo University
Hisakazu Yamane
Hisakazu Yamane Teikyo University
Hideoki Ogawa
Hideoki Ogawa Juntendo University
Kazuo Shin-ya
Kazuo Shin-ya National Institute of Advanced Industrial Science and Technology
Minoru Yoshida
Minoru Yoshida University of Tokyo
Shinya Fushinobu
Shinya Fushinobu University of Tokyo
Masaru Tanokura
Masaru Tanokura University of Tokyo

External Links

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Best Scientists Citing Makoto Nishiyama

Minoru Yoshida

Minoru Yoshida

University of Tokyo

Publications: 49

Sueharu Horinouchi

Sueharu Horinouchi

University of Tokyo

Publications: 47

Ko Okumura

Ko Okumura

Juntendo University

Publications: 43

Hisakazu Yamane

Hisakazu Yamane

Teikyo University

Publications: 39

Jeroen S. Dickschat

Jeroen S. Dickschat

University of Bonn

Publications: 35

Hideoki Ogawa

Hideoki Ogawa

Juntendo University

Publications: 34

Kazunori Okada

Kazunori Okada

University of Tokyo

Publications: 33

S. Samar Hasnain

S. Samar Hasnain

University of Liverpool

Publications: 28

Robert R. Eady

Robert R. Eady

University of Liverpool

Publications: 28

Teruhiko Beppu

Teruhiko Beppu

University of Tokyo

Publications: 24

Reuben J. Peters

Reuben J. Peters

Iowa State University

Publications: 24

Sakayu Shimizu

Sakayu Shimizu

Kyoto University

Publications: 23

Hideaki Nojiri

Hideaki Nojiri

University of Tokyo

Publications: 20

Shu-Ming Li

Shu-Ming Li

Philipp University of Marburg

Publications: 19

Tomohisa Kuzuyama

Tomohisa Kuzuyama

University of Tokyo

Publications: 18

Michael E. P. Murphy

Michael E. P. Murphy

University of British Columbia

Publications: 18

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