What is he best known for?
The fields of study he is best known for:
Makoto Nishiyama mainly investigates Biochemistry, Molecular biology, Biosynthesis, Nucleic acid sequence and Nitrile hydratase.
His Biochemistry study is mostly concerned with Amino acid, Amidase, Cyclase, ATP synthase and Thermus thermophilus.
He combines subjects such as Cell, Transcription factor, Mutant and Malate dehydrogenase with his study of Molecular biology.
As a part of the same scientific study, Makoto Nishiyama usually deals with the Mutant, concentrating on Metal and frequently concerns with Stereochemistry.
Makoto Nishiyama has included themes like Open reading frame and Coding region in his Nucleic acid sequence study.
His biological study spans a wide range of topics, including Protein subunit and Escherichia coli.
His most cited work include:
- FK228 (Depsipeptide) as a Natural Prodrug That Inhibits Class I Histone Deacetylases (623 citations)
- Histone deacetylase as a new target for cancer chemotherapy. (201 citations)
- X-ray structure and site-directed mutagenesis of a nitrite reductase from Alcaligenes faecalis S-6: roles of two copper atoms in nitrite reduction. (134 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Biochemistry, Stereochemistry, Thermus thermophilus, Enzyme and Biosynthesis.
His study in Lysine, Amino acid, Gene cluster, Gene and Protein subunit is done as part of Biochemistry.
The concepts of his Gene study are interwoven with issues in Molecular biology and DNA.
Makoto Nishiyama focuses mostly in the field of Stereochemistry, narrowing it down to topics relating to Alcaligenes faecalis and, in certain cases, Electron transfer.
In his research, Chymosin is intimately related to Site-directed mutagenesis, which falls under the overarching field of Enzyme.
The various areas that Makoto Nishiyama examines in his Biosynthesis study include ATP synthase and Streptomyces.
He most often published in these fields:
- Biochemistry (53.26%)
- Stereochemistry (31.16%)
- Thermus thermophilus (22.46%)
What were the highlights of his more recent work (between 2013-2021)?
- Biochemistry (53.26%)
- Stereochemistry (31.16%)
- Biosynthesis (16.67%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Biochemistry, Stereochemistry, Biosynthesis, Enzyme and Crystal structure.
His Lysine, Amino acid, Thermus thermophilus, Corynebacterium glutamicum and Dehydrogenase study are his primary interests in Biochemistry.
His studies in Stereochemistry integrate themes in fields like Cofactor, Carbazole, Ring and ATP synthase.
His Biosynthesis study incorporates themes from Stereoisomerism, Mutant, Aspartate kinase, Streptomyces and Reaction mechanism.
His research in Streptomyces intersects with topics in Metabolite and Gene cluster, Gene.
His Enzyme study combines topics from a wide range of disciplines, such as Sulfolobus acidocaldarius and Thiamine.
Between 2013 and 2021, his most popular works were:
- Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways. (95 citations)
- Changes in the Acetylome and Succinylome of Bacillus subtilis in Response to Carbon Source (75 citations)
- Biosynthesis of Versipelostatin: Identification of an Enzyme-Catalyzed [4+2]-Cycloaddition Required for Macrocyclization of Spirotetronate-Containing Polyketides (64 citations)
In his most recent research, the most cited papers focused on:
Biochemistry, Biosynthesis, Stereochemistry, Lysine and Streptomyces are his primary areas of study.
His work in Enzyme, Amino acid, Corynebacterium glutamicum, Mutant and Antibiotics are all subfields of Biochemistry research.
His work carried out in the field of Biosynthesis brings together such families of science as Amino acid kinase, Transferase, Function, Monoterpene and DNA sequencing.
He has researched Stereochemistry in several fields, including Biocatalysis, Ring and Stereoisomerism.
The Lysine study combines topics in areas such as Peptide sequence, Isothermal titration calorimetry and Thermus thermophilus.
His Streptomyces research is multidisciplinary, incorporating perspectives in Metabolite, Gene cluster, Gene and Nucleoside.
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