World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
61
Citations
13414
World Ranking
9232
National Ranking
2610

Overview

A. Joshua Wand is affiliated with the University of Pennsylvania in the United States and has contributed to research primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work encompasses various subfields including Molecular Biology, Materials Chemistry, Cellular and Molecular Neuroscience, Atomic and Molecular Physics and Optics, and Cell Biology.

The scientist's research topics focus on areas such as Protein Structure and Dynamics, Lipid Membrane Structure and Behavior, Enzyme Structure and Function, Photoreceptor and Optogenetics Research, Spectroscopy and Quantum Chemical Studies, Hemoglobin Structure and Function, and the Effects of Spaceflight on Biology.

Recent publications by A. Joshua Wand include the following papers:

  • The Molecular Basis for Life in Extreme Environments, 2021, Annual Review of Biophysics
  • Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases, 2021, Journal of Medicinal Chemistry
  • Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer, 2020, Journal of Biological Chemistry
  • Membrane Proteins Have Distinct Fast Internal Motion and Residual Conformational Entropy, 2020, Angewandte Chemie International Edition
  • Protein conformational entropy is not slaved to water, 2020, Scientific Reports

A. Joshua Wand frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), Annual Review of Biophysics, Journal of Medicinal Chemistry, Journal of Biological Chemistry, and Nature Communications.

The scientist often collaborates with co-authors including Brian Fuglestad, Matthew A. Stetz, Bryan S. Marques, Evan S. O'Brien, and Henry J. Lessen, reflecting interdisciplinary cooperation across multiple publications.

Best Publications

  • Conformational entropy in molecular recognition by proteins

    Kendra King Frederick;Michael S. Marlow;Kathleen G. Valentine;A. Joshua Wand

  • Design and synthesis of multi-haem proteins

    D E Robertson;R S Farid;C C Moser;J L Urbauer

  • Redistribution and loss of side chain entropy upon formation of a calmodulin-peptide complex

    Andrew L. Lee;Sandra A. Kinnear;A. Joshua Wand

  • Microscopic origins of entropy, heat capacity and the glass transition in proteins

    Andrew L. Lee;Andrew L. Lee;A. Joshua Wand

  • Characterization of the fast dynamics of protein amino acid side chains using NMR relaxation in solution.

    Tatyana I. Igumenova;Tatyana I. Igumenova;Kendra King Frederick;A. Joshua Wand

  • Assignment of the backbone resonances for microcrystalline ubiquitin.

    Tatyana I. Igumenova;A. Joshua Wand;Ann E. Mcdermott

  • Dynamic activation of protein function: A view emerging from NMR spectroscopy

    Unknown

  • Structural description of acid-denatured cytochrome c by hydrogen exchange and 2D NMR.

    Unknown

  • The role of conformational entropy in molecular recognition by calmodulin

    Michael S Marlow;Jakob Dogan;Kendra K Frederick;Kathleen G Valentine

  • Protein Structure Determination by High-Resolution Solid-State NMR Spectroscopy: Application to Microcrystalline Ubiquitin

    Stephan G. Zech;A. Joshua Wand;Ann E. Mcdermott

  • Assignments of carbon NMR resonances for microcrystalline ubiquitin.

    Tatyana I. Igumenova;Ann E. McDermott;Kurt W. Zilm;Rachel W. Martin

  • Insights into the local residual entropy of proteins provided by NMR relaxation

    Zhigang Li;Soumya Raychaudhuri;A. Joshua Wand

  • Site-resolved measurement of water-protein interactions by solution NMR

    Nathaniel V Nucci;Maxim S Pometun;A Joshua Wand

  • The Reorganization Energy of Cytochrome c Revisited

    Ingo Muegge;Phoebe X. Qi;A. Joshua Wand;Zhen T. Chu

  • The dark energy of proteins comes to light: conformational entropy and its role in protein function revealed by NMR relaxation

    A Joshua Wand

  • Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains.

    Renhao Li;Charles R. Babu;James D. Lear;A. Joshua Wand

  • Model-independent and model-dependent analysis of the global and internal dynamics of cyclosporin A

    Martin J. Dellwo;A. Joshua Wand

  • Water magnetic relaxation dispersion in biological systems: The contribution of proton exchange and implications for the noninvasive detection of cartilage degradation

    Umamaheswar Duvvuri;Ari D. Goldberg;James K. Kranz;Linh Hoang

  • Entropy in molecular recognition by proteins.

    José A Caro;Kyle W Harpole;Vignesh Kasinath;Jackwee Lim

  • Direct access to the cooperative substructure of proteins and the protein ensemble via cold denaturation.

    Charles R Babu;Vincent J Hilser;A Joshua Wand

  • High-resolution NMR of encapsulated proteins dissolved in low-viscosity fluids

    A. Joshua Wand;Mark R. Ehrhardt;Peter F. Flynn

  • De novo proteins as models of radical enzymes.

    Unknown

  • Mapping the hydration dynamics of ubiquitin.

    Nathaniel V. Nucci;Maxim S. Pometun;A. Joshua Wand

Frequent Co-Authors

Kim A. Sharp
Kim A. Sharp University of Pennsylvania
William F. DeGrado
William F. DeGrado University of California, San Francisco
P. Leslie Dutton
P. Leslie Dutton University of Pennsylvania
S. Walter Englander
S. Walter Englander University of Pennsylvania
Joel S. Bennett
Joel S. Bennett University of Pennsylvania
Vincent J. Hilser
Vincent J. Hilser Johns Hopkins University
James D. Lear
James D. Lear University of Pennsylvania
Ann E. McDermott
Ann E. McDermott Columbia University

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