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Tohru Mizushima

Tohru Mizushima

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
13862
World Ranking
9728
National Ranking
651

Overview

Tohru Mizushima is affiliated with Keio University in Japan, focusing their research primarily within the field of Medicine. Their scholarly contributions include multiple studies in subfields such as Pulmonary and Respiratory Medicine, Oncology, Physiology, Hematology, and Pharmacology.

The scientist's research covers a range of main topics, including:

  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Cancer Treatment and Pharmacology
  • Multiple Myeloma Research and Treatments
  • Inflammatory mediators and NSAID effects
  • Helicobacter pylori-related gastroenterology studies
  • Acute Kidney Injury Research
  • Cardiac Ischemia and Reperfusion

Recent papers authored or coauthored by Mizushima reflect ongoing engagement with these topics, illustrating a diverse and evolving research portfolio. Selected publications include:

  • "Novel pharmacological effects of lecithinized superoxide dismutase on ischemia/reperfusion injury in the kidneys of mice," 2021, Life Sciences
  • "A2B adenosine receptor inhibition by the dihydropyridine calcium channel blocker nifedipine involves colonic fluid secretion," 2020, Scientific Reports
  • "Repurposing the PDMA-approved drugs in Japan using an insect model of staphylococcal infection," 2022, FEMS Microbes
  • "Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity," 2022, Cell Death Discovery
  • "An Electron Paramagnetic Resonance Study of the Superoxide-Scavenging and Redox-Modulating Effects of Lecithinized Superoxide Dismutase in the Bloodstream," 2025, Molecules

Mizushima frequently publishes in venues including the Proceedings for Annual Meeting of The Japanese Pharmacological Society, Life Sciences, FEMS Microbes, Scientific Reports, and Cell Death Discovery. Collaboration is a notable aspect of their work, with frequent co-authors such as Ken-ichiro Tanaka, Naoki Yamakawa, Mikako Shimoda, Ayaka Takafuji, and Masahiro Kawahara.

Best Publications

  • NorM, a Putative Multidrug Efflux Protein, of Vibrio parahaemolyticus and Its Homolog in Escherichia coli

    Yuji Morita;Kazuyo Kodama;Sumiko Shiota;Tomoyuki Mine

  • The Highly Conserved DRY Motif of Class A G Protein-Coupled Receptors: Beyond the Ground State

    G. Enrico Rovati;Valérie Capra;Richard R. Neubig

  • An Autophagic Flux Probe that Releases an Internal Control

    Takeshi Kaizuka;Hideaki Morishita;Yutaro Hama;Satoshi Tsukamoto

  • Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa.

    Tomoyuki Mine;Yuji Morita;Atsuko Kataoka;Tohru Mizushima

  • Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis

    S. Tsutsumi;T. Gotoh;W. Tomisato;S. Mima

  • AbeM, an H+-Coupled Acinetobacter baumannii Multidrug Efflux Pump Belonging to the MATE Family of Transporters

    Xian Zhong Su;Jing Chen;Tohru Mizushima;Teruo Kuroda

  • NorM of Vibrio parahaemolyticus Is an Na+-Driven Multidrug Efflux Pump

    Yuji Morita;Atsuko Kataoka;Sumiko Shiota;Tohru Mizushima

  • Mechanisms of Action of Corilagin and Tellimagrandin I That Remarkably Potentiate the Activity of β-Lactams against Methicillin-Resistant Staphylococcus aureus

    Sumiko Shiota;Masato Shimizu;Jun'ichi Sugiyama;Yuji Morita

  • Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice

    Tatsuya Hoshino;Naoya Murao;Takushi Namba;Masaya Takehara

  • Prostaglandin E2 protects gastric mucosal cells from apoptosis via EP2 and EP4 receptor activation.

    Tatsuya Hoshino;Shinji Tsutsumi;Wataru Tomisato;Hyun Jung Hwang

  • EfrAB, an ABC Multidrug Efflux Pump in Enterococcus faecalis

    Eun Woo Lee;M. Nazmul Huda;Teruo Kuroda;Tohru Mizushima

  • Remarkable Synergies between Baicalein and Tetracycline, and Baicalein and β‐Lactams against Methicillin‐Resistant Staphylococcus aureus

    Mai Fujita;Sumiko Shiota;Teruo Kuroda;Tsutomu Hatano

  • A Putative Multisubunit Na+/H+ Antiporter from Staphylococcus aureus

    Toshiaki Hiramatsu;Kazuyo Kodama;Teruo Kuroda;Tohru Mizushima

  • Genetic Evidence for a Protective Role for Heat Shock Factor 1 and Heat Shock Protein 70 against Colitis

    Ken Ichiro Tanaka;Takushi Namba;Yasuhiro Arai;Mitsuaki Fujimoto

  • Marked Potentiation of Activity of β-Lactams against Methicillin-Resistant Staphylococcus aureus by Corilagin

    Masato Shimizu;Sumiko Shiota;Tohru Mizushima;Hideyuki Ito

  • VmrA, a member of a novel class of Na+-coupled multidrug efflux pumps from Vibrio parahaemolyticus

    J. Chen;Y. Morita;M. N. Huda;T. Kuroda

  • An H+-Coupled Multidrug Efflux Pump, PmpM, a Member of the MATE Family of Transporters, from Pseudomonas aeruginosa

    Gui Xin He;Teruo Kuroda;Takehiko Mima;Yuji Morita

  • A new member of the tripartite multidrug efflux pumps, MexVW–OprM, in Pseudomonas aeruginosa

    Yang Li;Takehiko Mima;Yukiko Komori;Yuji Morita

  • Marked reduction in the minimum inhibitory concentration (MIC) of β- lactams in methicillin-resistant Staphylococcus aureus produced by epicatechin gallate, an ingredient of green tea (Camellia sinensis)

    Sumiko Shiota;Masato Shimizu;Tohru Mizushima;Hideyuki Ito

  • Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro.

    Tohru Mizushima;Naoko Takahashi;Naoko Takahashi;Bruce Stillman

Frequent Co-Authors

Tomofusa Tsuchiya
Tomofusa Tsuchiya Okayama University
Kazuhisa Sekimizu
Kazuhisa Sekimizu University of Tokyo
Kazuhito Rokutan
Kazuhito Rokutan University of Tokushima
Tsutomu Katayama
Tsutomu Katayama Kyushu University
Hidekazu Suzuki
Hidekazu Suzuki Tokai University
Akira Nakai
Akira Nakai Yamaguchi University
Hiroaki Adachi
Hiroaki Adachi University of East Anglia
Toru Maruyama
Toru Maruyama Kumamoto University
Gen Sobue
Gen Sobue Aichi Medical University
Hirotada Mori
Hirotada Mori Nara Institute of Science and Technology

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