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D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
21447
World Ranking
11699
National Ranking
902

Overview

Hiroaki Adachi is affiliated with the University of East Anglia in the United Kingdom and has focused research efforts in the field of Medicine, with specific attention to Neurology, Cellular and Molecular Neuroscience, Psychiatry and Mental Health, Genetics, and Molecular Biology.

Their recent publications cover a range of topics primarily related to neurodegenerative diseases and molecular diagnostic methods. Selected works include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition), 2021, Americanae (AECID Library)
  • Rapid and comprehensive diagnostic method for repeat expansion diseases using nanopore sequencing, 2022, npj Genomic Medicine
  • Complete sequencing of expanded SAMD12 repeats by long-read sequencing and Cas9-mediated enrichment, 2021, Brain
  • CSF GAP-43 as a biomarker of synaptic dysfunction is associated with tau pathology in Alzheimer's disease, 2022, Scientific Reports
  • Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation, 2020, Brain

Frequent co-authors in their research include:

  • Tomoko Toyota
  • Satoru Ide
  • Qiang Qiang
  • Loren Skudder-Hill
  • Shingo Kakeda

Publications have appeared repeatedly in the following venues:

  • Scientific Reports
  • Brain
  • Journal of the Neurological Sciences
  • Journal of Neurology
  • Research Square (Research Square)

Key research topics associated with Hiroaki Adachi's work include:

  • Alzheimer's disease research and treatments
  • Parkinson's Disease Mechanisms and Treatments
  • Genetic Neurodegenerative Diseases
  • Dementia and Cognitive Impairment Research
  • Eating Disorders and Behaviors
  • Obsessive-Compulsive Spectrum Disorders
  • Neurogenetic and Muscular Disorders Research

Hiroaki Adachi's research contributions intersect interdisciplinary areas involving neurological disorders, genetic factors, and molecular biology, reflecting a focus on understanding disease mechanisms and improving diagnostic approaches.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.

    Masahisa Katsuno;Hiroaki Adachi;Akito Kume;Mei Li

  • 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration.

    Masahiro Waza;Hiroaki Adachi;Masahisa Katsuno;Makoto Minamiyama

  • A Receptor Pair with an Integrated Decoy Converts Pathogen Disabling of Transcription Factors to Immunity

    Clémentine Le Roux;Clémentine Le Roux;Clémentine Le Roux;Gaëlle Huet;Gaëlle Huet;Alain Jauneau;Laurent Camborde;Laurent Camborde

  • Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

    Masahisa Katsuno;Hiroaki Adachi;Manabu Doyu;Makoto Minamiyama

  • Heat Shock Protein 70 Chaperone Overexpression Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model by Reducing Nuclear-Localized Mutant Androgen Receptor Protein

    Hiroaki Adachi;Masahisa Katsuno;Makoto Minamiyama;Chen Sang

  • Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

    Makoto Minamiyama;Masahisa Katsuno;Hiroaki Adachi;Masahiro Waza

  • Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease.

    Masahisa Katsuno;Chen Sang;Hiroaki Adachi;Makoto Minamiyama

  • Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis

    Yue-Mei Jiang;Masahiko Yamamoto;Yasushi Kobayashi;Tsuyoshi Yoshihara

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients.

    Hiroaki Adachi;Masahisa Katsuno;Makoto Minamiyama;Masahiro Waza

  • WRKY Transcription Factors Phosphorylated by MAPK Regulate a Plant Immune NADPH Oxidase in Nicotiana benthamiana

    Hiroaki Adachi;Takaaki Nakano;Noriko Miyagawa;Nobuaki Ishihama

  • An N-terminal motif in NLR immune receptors is functionally conserved across distantly related plant species.

    Hiroaki Adachi;Mauricio P Contreras;Adeline Harant;Chih-hang Wu

  • Overexpression of IGF-1 in muscle attenuates disease in a mouse model of spinal and bulbar muscular atrophy.

    Isabella Palazzolo;Conor Stack;Lingling Kong;Antonio Musaro

  • Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice

    Tatsuya Hoshino;Naoya Murao;Takushi Namba;Masaya Takehara

  • NLR singletons, pairs, and networks: evolution, assembly, and regulation of the intracellular immunoreceptor circuitry of plants.

    Hiroaki Adachi;Lida Derevnina;Sophien Kamoun

  • CHIP Overexpression Reduces Mutant Androgen Receptor Protein and Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model

    Hiroaki Adachi;Masahiro Waza;Keisuke Tokui;Masahisa Katsuno

  • Clinicopathological features of neuropathy associated with lymphoma.

    Minoru Tomita;Haruki Koike;Yuichi Kawagashira;Masahiro Iijima

  • Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2

    Yu Miyazaki;Hiroaki Adachi;Masahisa Katsuno;Makoto Minamiyama

Frequent Co-Authors

Gen Sobue
Gen Sobue Aichi Medical University
Masahisa Katsuno
Masahisa Katsuno Nagoya University
Fumiaki Tanaka
Fumiaki Tanaka Yokohama City University
Yusuke Mori
Yusuke Mori Osaka University
Kazufumi Takano
Kazufumi Takano Kyoto Prefectural University
Tsuyoshi Inoue
Tsuyoshi Inoue Osaka University
Masashi Yoshimura
Masashi Yoshimura Osaka University
Sophien Kamoun
Sophien Kamoun University of East Anglia
Andrew P. Lieberman
Andrew P. Lieberman University of Michigan–Ann Arbor
Hirofumi Yoshioka
Hirofumi Yoshioka Nagoya University

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