World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
89
Citations
28029
World Ranking
2172
National Ranking
783

Research.com Recognitions

  • 2006 - Fellow of the American Academy of Arts and Sciences
  • 1998 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1997 - Member of the National Academy of Sciences

Overview

S. Walter Englander is affiliated with the University of Pennsylvania in the United States and has a research focus within the broad discipline of Biochemistry, Genetics, and Molecular Biology. They have contributed extensively to subfields such as Molecular Biology, Genetics, Cell Biology, Spectroscopy, and Oncology.

The scientist's main topics of study span several areas, including:

  • Protein Structure and Dynamics
  • Heat shock proteins research
  • Wnt/β-catenin signaling in development and cancer
  • Cancer-related gene regulation
  • Fibroblast Growth Factor Research
  • Mass Spectrometry Techniques and Applications
  • Ubiquitin and proteasome pathways

Englander has published research in several notable venues, with a frequent presence in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • Cell Reports
  • Annual Review of Biophysics

Recent publications by S. Walter Englander include:

  • "Structural and kinetic basis for the regulation and potentiation of Hsp104 function," 2020, Proceedings of the National Academy of Sciences
  • "ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes," 2021, Cell Reports
  • "Characterization of Small-Molecule-Induced Changes in Parkinson's-Related Trafficking via the Nedd4 Ubiquitin Signaling Cascade," 2020, Cell chemical biology
  • "HX and Me: Understanding Allostery, Folding, and Protein Machines," 2023, Annual Review of Biophysics
  • "A conserved strategy for structure change and energy transduction in Hsp104 and other AAA+ protein motors," 2021, Journal of Biological Chemistry

The scientist has collaborated frequently with researchers including Leland Mayne, A. Katherine Hatstat, Hannah Ahrendt, Matthew W. Foster, and M. Arthur Moseley.

S. Walter Englander has received several recognitions during their career, such as being named a Fellow of the American Academy of Arts and Sciences in 2006 and a Fellow of the American Association for the Advancement of Science (AAAS) in 1998. They have also been a Member of the National Academy of Sciences since 1997.

Best Publications

  • Primary structure effects on peptide group hydrogen exchange

    Unknown

  • Hydrogen exchange and structural dynamics of proteins and nucleic acids

    Englander Sw;Kallenbach Nr

  • Protein Folding Intermediates: Native-State Hydrogen Exchange

    Yawen Bai;T. R. Sosnick;L. Mayne;S. W. Englander

  • Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR

    Heinrich Roder;Gülnur A. Elöve;S. Walter Englander

  • Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

    Glenn R. Masson;John E. Burke;Natalie G. Ahn;Ganesh S. Anand

  • Nature of the open state in long polynucleotide double helices: possibility of soliton excitations

    S W Englander;N R Kallenbach;A J Heeger;J A Krumhansl

  • Primary structure effects on peptide group hydrogen exchange.

    R S Molday;S W Englander;R G Kallen

  • The barriers in protein folding

    T.R. Sosnick;L. Mayne;R. Hiller;S.W. Englander

  • Mechanisms and uses of hydrogen exchange

    S Walter Englander;Tobin R Sosnick;Joan J Englander;Leland Mayne

  • The E46K Mutation in α-Synuclein Increases Amyloid Fibril Formation

    Eric A. Greenbaum;Charles L. Graves;Amanda J. Mishizen-Eberz;Michael A. Lupoli

  • Isotope effects in peptide group hydrogen exchange

    Gregory P. Connelly;Yawen Bai;Mei‐Fen ‐F Jeng;S. Walter Englander

  • Hydrogen exchange and mass spectrometry: A historical perspective.

    S. Walter Englander

  • Protein stability parameters measured by hydrogen exchange

    Yawen Bai;John S. Milne;Leland Mayne;S. Walter Englander

  • The nature of protein folding pathways.

    S. Walter Englander;Leland Mayne

  • Urea, but not guanidinium, destabilizes proteins by forming hydrogen bonds to the peptide group

    Woon Ki Lim;Jörg Rösgen;S. Walter Englander

  • Hydrogen exchange methods to study protein folding.

    Mallela M G Krishna;Linh Hoang;Yan Lin;S Walter Englander

  • Protein folding: The stepwise assembly of foldon units

    Haripada Maity;Mita Maity;Mallela M. G. Krishna;Leland Mayne

  • Hydrogen exchange: The modern legacy of Linderstrøm-Lang

    S. W. Englander;L. Mayne;Y. Bai;T. R. Sosnick

  • Chaperonin function: folding by forced unfolding.

    Mark Shtilerman;George H. Lorimer;S. Walter Englander

  • Protein folding intermediates and pathways studied by hydrogen exchange.

    Unknown

  • Stable submolecular folding units in a non-compact form of cytochrome c.

    Mei Fen Jeng;S. Walter Englander

  • Protein structure change studied by hydrogen-deuterium exchange, functional labeling, and mass spectrometry.

    Joan J. Englander;Charyl Del Mar;Will Li;S. Walter Englander

  • Structure and properties of α-synuclein and other amyloids determined at the amino acid level

    Charyl Del Mar;Eric A. Greenbaum;Leland Mayne;S. Walter Englander

  • Protein folding and misfolding: mechanism and principles

    S. Walter Englander;Leland Mayne;Mallela M. G. Krishna

  • Future directions in folding: the multi-state nature of protein structure.

    Yawen Bai;S. Walter Englander

  • RESEARCH ARTICLES Molecular Collapse: The Rate-Limiting Step in Two-State Cytochrome c Folding

    Tobin R. Sosnick;Leland Mayne;S. Walter Englander

Frequent Co-Authors

Tobin R. Sosnick
Tobin R. Sosnick University of Chicago
Neville R. Kallenbach
Neville R. Kallenbach New York University
Ben E. Black
Ben E. Black University of Pennsylvania
Michael C. Phillips
Michael C. Phillips University of Pennsylvania
Sissel Lund-Katz
Sissel Lund-Katz University of Pennsylvania
A. Joshua Wand
A. Joshua Wand University of Pennsylvania
James Shorter
James Shorter University of Pennsylvania
Virgil L. Woods
Virgil L. Woods University of California, San Diego
William F. DeGrado
William F. DeGrado University of California, San Francisco
Benjamin A. Garcia
Benjamin A. Garcia Washington University in St. Louis

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