World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
58
Citations
8588
World Ranking
10896
National Ranking
796

Overview

Kazuyuki Akasaka is affiliated with Kyoto Prefectural University of Medicine in Japan. Their research spans multiple fields, primarily focusing on biochemistry, genetics, and molecular biology, as well as energy sectors. Within these main fields, their work touches on several subfields including molecular biology, renewable energy, sustainability and the environment, atomic and molecular physics and optics, materials chemistry, and electrical and electronic engineering.

The scientist's research interests are concentrated around specific topics such as algal biology and biofuel production, protein structure and dynamics, spectroscopy and quantum chemical studies, enzyme structure and function, photosynthetic processes and mechanisms, and electrochemical sensors and biosensors.

Among their recent published papers are:

  • Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Microinjection System for Single-Microalgal Cells Based on Electroosmotic Flow, 2024, ECS Meeting Abstracts
  • Electroosmotic Flow-Based Nanoinjection Technique Using a Nanopipette for Green Microalgae, 2025, Marine Biotechnology

The scholar has coauthored scientific publications with several researchers, including Rein Yasui, Tomoko Yoshino, Daisuke Nojima, Tsuyoshi Tanaka, and Donald Gagné. The collaborations with these colleagues have involved multiple joint publications, with each listed coauthor appearing in at least two works except for Donald Gagné, who appears in one.

Kazuyuki Akasaka's work has been published in diverse venues such as bioRxiv (Cold Spring Harbor Laboratory), ECS Meeting Abstracts, and Marine Biotechnology. These publication outlets reflect the interdisciplinary nature of their research, bridging biochemistry, molecular biology, and energy-related sciences.

Best Publications

  • Probing conformational fluctuation of proteins by pressure perturbation.

    Kazuyuki Akasaka

  • NMR snapshots of a fluctuating protein structure: ubiquitin at 30 bar-3 kbar.

    Ryo Kitahara;Shigeyuki Yokoyama;Kazuyuki Akasaka

  • Pressure-dependent changes in the solution structure of hen egg-white lysozyme.

    Mohamed Refaee;Tomoko Tezuka;Kazuyuki Akasaka;Michael P. Williamson

  • Chemical shielding tensor and 13C–14N dipolar splitting in single crystals of L‐alanine

    A. Naito;S. Ganapathy;K. Akasaka;C. A. McDowell

  • The Methanol-induced Globular and Expanded Denatured States of Cytochromec: A Study by CD Fluorescence, NMR and Small-angle X-ray Scattering

    Yuji O. Kamatari;Yuji O. Kamatari;Takashi Konno;Takashi Konno;Mikio Kataoka;Mikio Kataoka;Kazuyuki Akasaka;Kazuyuki Akasaka

  • Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc?

    Kazuo Kuwata;Hua Li;Hiroaki Yamada;Giuseppe Legname

  • Effect of pressure on individual hydrogen bonds in proteins. Basic pancreatic trypsin inhibitor.

    Hua Li;Hiroaki Yamada;Kazuyuki Akasaka

  • 1H NMR application for characterizing water-soluble organic compounds in urban atmospheric particles.

    Yukio Suzuki;Masaru Kawakami;Kazuyuki Akasaka

  • The pressure-temperature free energy-landscape of staphylococcal nuclease monitored by (1)H NMR.

    Michael W Lassalle;Hiroaki Yamada;Kazuyuki Akasaka

  • Pressure-induced changes in the folded structure of lysozyme

    Kazuyuki Akasaka;Tomoko Tezuka;Hiroaki Yamada

  • Close identity of a pressure-stabilized intermediate with a kinetic intermediate in protein folding.

    Ryo Kitahara;Kazuyuki Akasaka

  • Internal motions in myosin.

    S. Highsmith;K. Akasaka;Manfred Konrad;Roger S. Goody

  • High-pressure NMR spectroscopy for characterizing folding intermediates and denatured states of proteins.

    Yuji O. Kamatari;Ryo Kitahara;Hiroyuki Yamada;Shigeyuki Yokoyama

  • Low-lying excited states of proteins revealed from nonlinear pressure shifts in 1H and 15N NMR.

    Kazuyuki Akasaka;Hua Li

  • Pressure-dissociable reversible assembly of intrinsically denatured lysozyme is a precursor for amyloid fibrils

    Tara N. Niraula;Takashi Konno;Hua Li;Hiroaki Yamada

  • Pressure response of protein backbone structure. Pressure-induced amide 15N chemical shifts in BPTI.

    Kazuyuki Akasaka;Hua Li;Hiroaki Yamada;Renhao Li

  • Thermodynamics of unfolding of ribonuclease A under high pressure. A study by proton NMR

    Tohru Yamaguchi;Hiroaki Yamada;Kazuyuki Akasaka

  • Highly fluctuating protein structures revealed by variable-pressure nuclear magnetic resonance.

    Kazuyuki Akasaka

  • High pressure NMR reveals that apomyoglobin is an equilibrium mixture from the native to the unfolded.

    Ryo Kitahara;Hiroaki Yamada;Kazuyuki Akasaka;Peter E. Wright

  • Pressure-induced local unfolding of the Ras binding domain of RalGDS

    Kyoko Inoue;Hiroaki Yamada;Kazuyuki Akasaka;Christian Herrmann

  • High Pressure Bioscience

    Kazuyuki Akasaka;Hitoshi Matsuki

Frequent Co-Authors

Hans Robert Kalbitzer
Hans Robert Kalbitzer University of Regensburg
Michael P. Williamson
Michael P. Williamson University of Sheffield
Koichi Kato
Koichi Kato National Institutes of Natural Sciences
Yuji Goto
Yuji Goto Osaka University
Catherine A. Royer
Catherine A. Royer Rensselaer Polytechnic Institute
Mikio Kataoka
Mikio Kataoka Nara Institute of Science and Technology
Christopher M. Dobson
Christopher M. Dobson University of Cambridge
Frans A. A. Mulder
Frans A. A. Mulder Aarhus University
Yoshio Nosaka
Yoshio Nosaka Nagaoka University of Technology

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